Compile Data Set for Download or QSAR
Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 50048187
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207403(CHEMBL3911282)
Affinity DataEC50:  682nMAssay Description:Positive allosteric modulation of recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as potentiation of gluta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at recombinant human mGlu1 expressed in hamster AV12 cells expressing EAAT1 assessed as increase in intracellular calcium level meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as increase in intracellular calcium l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataEC50: >1.25E+4nMAssay Description:Positive allosteric modulation of recombinant human mGlu3 expressed in hamster AV12 cells expressing EAAT1 assessed as potentiation of glutamate-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207409(CHEMBL3892611)
Affinity DataEC50:  294nMAssay Description:Positive allosteric modulation of recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as potentiation of gluta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207408(CHEMBL3943547)
Affinity DataEC50:  1.08E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as potentiation of gluta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207407(CHEMBL3936830)
Affinity DataEC50:  39nMAssay Description:Positive allosteric modulation of recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as potentiation of gluta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207398(CHEMBL3965244)
Affinity DataEC50:  6nMAssay Description:Positive allosteric modulation of recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as potentiation of gluta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207406(CHEMBL3890848)
Affinity DataEC50:  405nMAssay Description:Positive allosteric modulation of recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as potentiation of gluta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207404(CHEMBL3935529)
Affinity DataEC50:  1.43E+3nMAssay Description:Positive allosteric modulation of recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as potentiation of gluta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207410(CHEMBL3909995)
Affinity DataEC50:  110nMAssay Description:Positive allosteric modulation of recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as potentiation of gluta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207399(CHEMBL3913281)
Affinity DataEC50:  470nMAssay Description:Positive allosteric modulation of recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as potentiation of gluta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207405(CHEMBL3918914)
Affinity DataEC50:  319nMAssay Description:Positive allosteric modulation of recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as potentiation of gluta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207411(CHEMBL3973048)
Affinity DataEC50:  18nMAssay Description:Positive allosteric modulation of recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as potentiation of gluta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataEC50: >1.25E+4nMAssay Description:Positive allosteric modulation of recombinant human mGlu5 expressed in hamster AV12 cells expressing EAAT1 assessed as potentiation of glutamate-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at recombinant human mGlu3 expressed in hamster AV12 cells expressing EAAT1 assessed as increase in intracellular calcium level meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataEC50:  201nMAssay Description:Positive allosteric modulation of recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as potentiation of gluta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207412(CHEMBL3920609)
Affinity DataEC50:  562nMAssay Description:Positive allosteric modulation of recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as potentiation of gluta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207402(CHEMBL3980125)
Affinity DataEC50:  227nMAssay Description:Positive allosteric modulation of recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as potentiation of gluta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataEC50: >2.50E+4nMAssay Description:Agonist activity at recombinant human mGlu5 expressed in hamster AV12 cells expressing EAAT1 assessed as increase in intracellular calcium level meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataEC50: >1.25E+4nMAssay Description:Positive allosteric modulation of recombinant human mGlu1 expressed in hamster AV12 cells expressing EAAT1 assessed as potentiation of glutamate-indu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207413(CHEMBL3945882)
Affinity DataEC50:  310nMAssay Description:Positive allosteric modulation of recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as potentiation of gluta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207397(CHEMBL3927834)
Affinity DataEC50:  87nMAssay Description:Positive allosteric modulation of recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as potentiation of gluta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207410(CHEMBL3909995)
Affinity DataIC50: 62nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207406(CHEMBL3890848)
Affinity DataIC50: 74nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207398(CHEMBL3965244)
Affinity DataIC50: 112nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207404(CHEMBL3935529)
Affinity DataIC50: 132nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207411(CHEMBL3973048)
Affinity DataIC50: 144nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207399(CHEMBL3913281)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207405(CHEMBL3918914)
Affinity DataIC50: 203nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207413(CHEMBL3945882)
Affinity DataIC50: 330nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207397(CHEMBL3927834)
Affinity DataIC50: 342nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207403(CHEMBL3911282)
Affinity DataIC50: 346nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207402(CHEMBL3980125)
Affinity DataIC50: 390nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207407(CHEMBL3936830)
Affinity DataIC50: 475nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207412(CHEMBL3920609)
Affinity DataIC50: 484nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207409(CHEMBL3892611)
Affinity DataIC50: 1.43E+3nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207408(CHEMBL3943547)
Affinity DataIC50: 1.50E+3nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in Syrian hamster AV12-664 cells assessed as decrease in LTD4-induced intracellular calcium le...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataIC50: 8.00E+3nMAssay Description:Antagonist activity at recombinant human mGlu1 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as inhibition of glutamate-induced ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataIC50: 1.25E+4nMAssay Description:Antagonist activity at recombinant human mGlu5 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as inhibition of glutamate-induced ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 3(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataIC50: 1.25E+4nMAssay Description:Antagonist activity at recombinant human mGlu3 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as inhibition of glutamate-induced ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 2(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataIC50: 1.25E+4nMAssay Description:Antagonist activity at recombinant human mGlu2 receptor expressed in hamster AV12 cells expressing EAAT1 assessed as inhibition of glutamate-induced ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataKi: >6.31E+6nMAssay Description:Displacement of human recombinant 5HT4E receptor expressed in CHO cells after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataKi: >3.98E+6nMAssay Description:Displacement of [3H]LSD from human 5HT7 receptor expressed in CHO cells after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 5A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataKi: >6.90E+6nMAssay Description:Displacement of human 5HT5A receptor expressed in HEK293 cells after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataKi: >7.87E+6nMAssay Description:Activity at human 5T2C receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1F(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataKi: >2.97E+6nMAssay Description:Activity at human 5HT1F receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataKi: >7.47E+6nMAssay Description:Activity at human 5HT2A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50207400(CHEMBL3899832)
Affinity DataKi: >3.58E+6nMAssay Description:Activity at human 5HT1B receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2018
Entry Details Article
PubMed
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