Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 6177
TargetDiacylglycerol O-acyltransferase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM113713(US8637507, C-71 isomer B | US8637507, C-70 isomer ...)
Affinity DataIC50: 36nMT: 2°CAssay Description:The in vitro assay to identify DGAT1 inhibitors uses human DGAT1 enzyme expressed in Sf9 insect cells prepared as microsomes. The reaction was initia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM113713(US8637507, C-71 isomer B | US8637507, C-70 isomer ...)
Affinity DataIC50: 54nMT: 2°CAssay Description:The in vitro assay to identify DGAT1 inhibitors uses human DGAT1 enzyme expressed in Sf9 insect cells prepared as microsomes. The reaction was initia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM113711(US8637507, C-65)
Affinity DataIC50: 60nMT: 2°CAssay Description:The in vitro assay to identify DGAT1 inhibitors uses human DGAT1 enzyme expressed in Sf9 insect cells prepared as microsomes. The reaction was initia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM113715(US8637507, C-87)
Affinity DataIC50: 67nMT: 2°CAssay Description:The in vitro assay to identify DGAT1 inhibitors uses human DGAT1 enzyme expressed in Sf9 insect cells prepared as microsomes. The reaction was initia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM113716(US8637507, C-91)
Affinity DataIC50: 85nMT: 2°CAssay Description:The in vitro assay to identify DGAT1 inhibitors uses human DGAT1 enzyme expressed in Sf9 insect cells prepared as microsomes. The reaction was initia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM113724(US8637507, B-13)
Affinity DataIC50: 87nMT: 2°CAssay Description:The in vitro assay to identify DGAT1 inhibitors uses human DGAT1 enzyme expressed in Sf9 insect cells prepared as microsomes. The reaction was initia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM113720(US8637507, C-5)
Affinity DataIC50: 118nMT: 2°CAssay Description:The in vitro assay to identify DGAT1 inhibitors uses human DGAT1 enzyme expressed in Sf9 insect cells prepared as microsomes. The reaction was initia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM113721(US8637507, C-8)
Affinity DataIC50: 119nMT: 2°CAssay Description:The in vitro assay to identify DGAT1 inhibitors uses human DGAT1 enzyme expressed in Sf9 insect cells prepared as microsomes. The reaction was initia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM113719(US8637507, C-3)
Affinity DataIC50: 131nMT: 2°CAssay Description:The in vitro assay to identify DGAT1 inhibitors uses human DGAT1 enzyme expressed in Sf9 insect cells prepared as microsomes. The reaction was initia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM113725(US8637507, C-56)
Affinity DataIC50: 131nMT: 2°CAssay Description:The in vitro assay to identify DGAT1 inhibitors uses human DGAT1 enzyme expressed in Sf9 insect cells prepared as microsomes. The reaction was initia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM113717(US8637507, B-4)
Affinity DataIC50: 138nMT: 2°CAssay Description:The in vitro assay to identify DGAT1 inhibitors uses human DGAT1 enzyme expressed in Sf9 insect cells prepared as microsomes. The reaction was initia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM113712(US8637507, C-68)
Affinity DataIC50: 156nMT: 2°CAssay Description:The in vitro assay to identify DGAT1 inhibitors uses human DGAT1 enzyme expressed in Sf9 insect cells prepared as microsomes. The reaction was initia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM113718(US8637507, C-1)
Affinity DataIC50: 254nMT: 2°CAssay Description:The in vitro assay to identify DGAT1 inhibitors uses human DGAT1 enzyme expressed in Sf9 insect cells prepared as microsomes. The reaction was initia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM113723(US8637507, B-17)
Affinity DataIC50: 275nMT: 2°CAssay Description:The in vitro assay to identify DGAT1 inhibitors uses human DGAT1 enzyme expressed in Sf9 insect cells prepared as microsomes. The reaction was initia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM113722(US8637507, C-60)
Affinity DataIC50: 280nMT: 2°CAssay Description:The in vitro assay to identify DGAT1 inhibitors uses human DGAT1 enzyme expressed in Sf9 insect cells prepared as microsomes. The reaction was initia...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
US Patent