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Report error Found 39 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50036909
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086013(CHEMBL10009 | N-[2-(2-Methoxy-6H-isoindolo[2,1-a]i...)
Affinity DataKi:  0.0500nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086033(CHEMBL9772 | N-[2-(2-Methoxy-6H-isoindolo[2,1-a]in...)
Affinity DataKi:  0.0600nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086017(CHEMBL9997 | N-[2-(10-Methoxy-5,6-dihydro-indolo[2...)
Affinity DataKi:  0.120nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086004(CHEMBL9590 | N-[2-(2-Ethoxy-6H-isoindolo[2,1-a]ind...)
Affinity DataKi:  0.160nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086032(CHEMBL274317 | N-[2-(2-Methoxy-6H-isoindolo[2,1-a]...)
Affinity DataKi:  0.170nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086029(CHEMBL10099 | N-[2-(10-Methoxy-5,6-dihydro-indolo[...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086020(CHEMBL274896 | N-[2-(2-Ethoxy-6H-isoindolo[2,1-a]i...)
Affinity DataKi:  0.210nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086028(CHEMBL9630 | N-[2-(2-Ethoxy-6H-isoindolo[2,1-a]ind...)
Affinity DataKi:  0.260nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)
Affinity DataKi:  0.330nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086001(CHEMBL274438 | N-[2-(11-Methoxy-6,7-dihydro-5H-ben...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086005(CHEMBL274842 | N-[2-(10-Methoxy-5,6-dihydro-indolo...)
Affinity DataKi:  0.510nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086011(CHEMBL10110 | Cyclopropanecarboxylic acid [2-(2-me...)
Affinity DataKi:  0.950nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086025(CHEMBL10293 | N-[2-(11-Methoxy-6,7-dihydro-5H-benz...)
Affinity DataKi:  1.41nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086015(CHEMBL9605 | N-[2-(5,6-Dihydro-indolo[2,1-a]isoqui...)
Affinity DataKi:  3.70nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086021(CHEMBL274630 | N-[2-(11-Chloro-6,7-dihydro-5H-benz...)
Affinity DataKi:  5.01nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086026(CHEMBL9600 | Cyclopropanecarboxylic acid [2-(2-eth...)
Affinity DataKi:  5.5nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086022(CHEMBL275529 | N-[2-(11-Methoxy-6,7-dihydro-5H-ben...)
Affinity DataKi:  6.31nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086014(CHEMBL10007 | N-[2-(11-Ethoxy-6,7-dihydro-5H-benzo...)
Affinity DataKi:  6.46nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086008(CHEMBL273897 | N-[2-(5,6-Dihydro-indolo[2,1-a]isoq...)
Affinity DataKi:  9.33nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086010(CHEMBL10328 | N-[2-(6H-Isoindolo[2,1-a]indol-11-yl...)
Affinity DataKi:  12nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086035(CHEMBL10124 | Cyclopropanecarboxylic acid [2-(11-m...)
Affinity DataKi:  12nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086019(CHEMBL9765 | N-[2-(6H-Isoindolo[2,1-a]indol-11-yl)...)
Affinity DataKi:  17nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086009(CHEMBL269175 | N-[2-(6H-Isoindolo[2,1-a]indol-11-y...)
Affinity DataKi:  17.4nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086000(CHEMBL276005 | N-[2-(11-Ethoxy-6,7-dihydro-5H-benz...)
Affinity DataKi:  21.9nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086007(CHEMBL9917 | Cyclobutanecarboxylic acid [2-(11-met...)
Affinity DataKi:  31.6nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086034(CHEMBL273624 | N-[2-(2-Chloro-6H-isoindolo[2,1-a]i...)
Affinity DataKi:  33.9nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086036(CHEMBL9634 | N-[2-(5,6-Dihydro-indolo[2,1-a]isoqui...)
Affinity DataKi:  36.3nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM85065(CAS_117946-91-5 | Luzindole | NSC_122162)
Affinity DataKi:  44.7nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086003(CHEMBL9838 | N-[2-(6,7-Dihydro-5H-benzo[3,4]azepin...)
Affinity DataKi:  45.7nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086018(CHEMBL9791 | Cyclopropanecarboxylic acid [2-(6,7-d...)
Affinity DataKi:  52.5nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086024(CHEMBL9815 | N-[2-(6,7-Dihydro-5H-benzo[3,4]azepin...)
Affinity DataKi:  63.1nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086030(CHEMBL9935 | Cyclopropanecarboxylic acid [2-(11-et...)
Affinity DataKi:  85.1nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086016(CHEMBL274995 | N-[2-(11-Ethoxy-6,7-dihydro-5H-benz...)
Affinity DataKi:  117nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086027(CHEMBL273623 | N-[2-(6,7-Dihydro-5H-benzo[3,4]azep...)
Affinity DataKi:  224nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086023(CHEMBL10043 | Cyclopropanecarboxylic acid [2-(6H-i...)
Affinity DataKi:  224nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086002(CHEMBL269670 | Cyclobutanecarboxylic acid [2-(6,7-...)
Affinity DataKi:  309nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086006(CHEMBL276490 | Cyclobutanecarboxylic acid [2-(10-m...)
Affinity DataKi:  324nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086031(CHEMBL9950 | Cyclobutanecarboxylic acid [2-(5,6-di...)
Affinity DataKi:  355nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
King'S College London

Curated by ChEMBL
LigandPNGBDBM50086012(CHEMBL9934 | Cyclobutanecarboxylic acid [2-(6H-iso...)
Affinity DataKi:  1.12E+3nMAssay Description:Binding affinity towards recombinant human melatonin receptor type 1B expressed in NIH 3T3 cells using 2-[121I]iodomelatonin radioligand binding assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed