Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50044500
TargetProstaglandin E synthase(Human)
University of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50019160(CHEMBL3289100)
Affinity DataIC50: 400nMAssay Description:Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50019157(CHEMBL3289097)
Affinity DataIC50: 400nMAssay Description:Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50019154(CHEMBL3289107)
Affinity DataIC50: 900nMAssay Description:Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50303448(Beta-elemonic acid | CHEMBL566929)
Affinity DataIC50: 900nMAssay Description:Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50019162(CHEMBL3289103)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50019156(CHEMBL3289096 | CHEBI:10274)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50019158(CHEMBL3289098)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50006805(CHEMBL29097 | 3-(3-(tert-butylthio)-1-(4-chloroben...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50241261(11-keto-beta-boswellicacid | (3R,4R,4aR,6aR,6bS,8a...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50019163(CHEMBL236906 | Acetyl-Beta-Boswellic Acid)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50241262(3-O-acetyl-11-keto-beta-boswellic acid | 3alpha-ac...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50019159(CHEMBL3289099)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50241260(boswellic acid | (3R,4R,4aR,6aR,6bS,8aR,11R,12S,12...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50019152(CHEMBL3289105)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50019151(CHEMBL3289104)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50019153(CHEMBL3289106)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50019155(CHEMBL3289101)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProstaglandin E synthase(Human)
University of Tuebingen

Curated by ChEMBL
LigandPNGBDBM50019161(CHEMBL3289102)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of microsomal PGES1 isolated from IL-1beta-stimulated human A549 cells preincubated for 15 mins followed by substrate addition measured af...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed