Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50046352
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107587(CHEMBL3601910)
Affinity DataIC50: 2.40nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107535(CHEMBL3601902)
Affinity DataIC50: 7.5nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107532(CHEMBL3601900)
Affinity DataIC50: 8.20nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107588(CHEMBL3601911)
Affinity DataIC50: 8.80nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107539(CHEMBL3601906)
Affinity DataIC50: 9.30nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107538(CHEMBL3601905)
Affinity DataIC50: 9.70nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107424(CHEMBL3600421)
Affinity DataIC50: 10nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107428(CHEMBL3600426)
Affinity DataIC50: 13nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107429(CHEMBL3600427)
Affinity DataIC50: 13nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107452(CHEMBL3601898)
Affinity DataIC50: 15nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107585(CHEMBL3601908)
Affinity DataIC50: 17nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107426(CHEMBL3600424)
Affinity DataIC50: 23nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107422(CHEMBL3601915)
Affinity DataIC50: 28nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107435(CHEMBL3600433)
Affinity DataIC50: 29nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107423(CHEMBL3600420)
Affinity DataIC50: 31nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107537(CHEMBL3601904)
Affinity DataIC50: 31nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107534(CHEMBL3601901)
Affinity DataIC50: 31nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50084137(2-Methyl-6-phenylethynyl-pyridine | CHEMBL66654 | ...)
Affinity DataIC50: 32nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107586(CHEMBL3601909)
Affinity DataIC50: 38nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107425(CHEMBL3600423)
Affinity DataIC50: 42nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107431(CHEMBL3600430)
Affinity DataIC50: 44nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107395(CHEMBL3601912)
Affinity DataIC50: 56nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107421(CHEMBL3601913)
Affinity DataIC50: 56nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107430(CHEMBL3600429)
Affinity DataIC50: 60nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107427(CHEMBL3600425)
Affinity DataIC50: 71nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107432(CHEMBL3600431)
Affinity DataIC50: 182nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107433(CHEMBL3600432)
Affinity DataIC50: 584nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107533(CHEMBL3600401)
Affinity DataIC50: 978nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107531(CHEMBL3601899)
Affinity DataIC50: 1.00E+3nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107540(CHEMBL3601907)
Affinity DataIC50: 1.00E+3nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50107536(CHEMBL3601903)
Affinity DataIC50: 1.06E+3nMAssay Description:Negative allosteric modulator activity against human mGluR5 expressed in HEK293 cells assessed as inhibition of glutamate-induced inositol phosphate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2016
Entry Details Article
PubMed