Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 6855
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
University of Illinois At Chicago

LigandPNGBDBM31524(Naphthalene and Benzamide Derivative, 25 | 5-amino...)
Affinity DataIC50: 230nMpH: 7.5Assay Description:done in a single pass in black 384-well plates (Matrix Technologies). The SARS-PLpro enzyme (20 nM final concentration) was prepared in an assay buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
University of Illinois At Chicago

LigandPNGBDBM50007789(CHEMBL1173044 | GRL-0667 | N-(2H-1,3-benzodioxol-5...)
Affinity DataIC50: 980nMpH: 7.5Assay Description:done in a single pass in black 384-well plates (Matrix Technologies). The SARS-PLpro enzyme (20 nM final concentration) was prepared in an assay buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
University of Illinois At Chicago

LigandPNGBDBM31530(Substituted Benzamide Derivative, 49 | 2-methyl-5-...)
Affinity DataIC50: 1.18E+3nMpH: 7.5Assay Description:done in a single pass in black 384-well plates (Matrix Technologies). The SARS-PLpro enzyme (20 nM final concentration) was prepared in an assay buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
University of Illinois At Chicago

LigandPNGBDBM154574(N-(2H-1,3-benzodioxol-5-ylmethyl)-1-[(1S)-1-(napht...)
Affinity DataIC50: 2.26E+3nMpH: 7.5Assay Description:done in a single pass in black 384-well plates (Matrix Technologies). The SARS-PLpro enzyme (20 nM final concentration) was prepared in an assay buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetORF1a(Middle East respiratory syndrome coronavirus (Viru...)
University of Illinois At Chicago

LigandPNGBDBM154573(8-(trifluoromethyl)-9H-purin-6-amine (4) | jm5b014...)
Affinity DataKi:  7.60E+3nM IC50: 6.20E+3nMpH: 7.5Assay Description:done in a single pass in black 384-well plates (Matrix Technologies). The SARS-PLpro enzyme (20 nM final concentration) was prepared in an assay buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab [1541-1855](Human SARS coronavirus (SARS-CoV))
University of Illinois At Chicago

LigandPNGBDBM154573(8-(trifluoromethyl)-9H-purin-6-amine (4) | jm5b014...)
Affinity DataKi:  1.15E+4nM IC50: 1.09E+4nMpH: 7.5Assay Description:done in a single pass in black 384-well plates (Matrix Technologies). The SARS-PLpro enzyme (20 nM final concentration) was prepared in an assay buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed