Compile Data Set for Download or QSAR
maximum 50k data
Found 21 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 7756
TargetCytochrome P450 1A2(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM214689(US9295672, (S)-(4-fluorophenyl)(4-((5-methyl-1H-py...)
Affinity DataIC50: <310nMT: 2°CAssay Description:The ability of the R and S enantiomers of (4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol to inhibit the common drug met...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 1A2(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM214688(US9295672, (4-fluorophenyl)(4-((5-methyl-1H-pyraz...)
Affinity DataIC50: <310nMT: 2°CAssay Description:The ability of the R and S enantiomers of (4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol to inhibit the common drug met...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 1A2(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM214690(US9295672, (R)-(4-fluorophenyl)(4-((5-methyl-1H-py...)
Affinity DataIC50:  1.70E+3nMT: 2°CAssay Description:The ability of the R and S enantiomers of (4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol to inhibit the common drug met...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM214689(US9295672, (S)-(4-fluorophenyl)(4-((5-methyl-1H-py...)
Affinity DataIC50:  1.05E+4nMT: 2°CAssay Description:The ability of the R and S enantiomers of (4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol to inhibit the common drug met...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM214688(US9295672, (4-fluorophenyl)(4-((5-methyl-1H-pyraz...)
Affinity DataIC50:  1.09E+4nMT: 2°CAssay Description:The ability of the R and S enantiomers of (4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol to inhibit the common drug met...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C19(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM214690(US9295672, (R)-(4-fluorophenyl)(4-((5-methyl-1H-py...)
Affinity DataIC50:  1.18E+4nMT: 2°CAssay Description:The ability of the R and S enantiomers of (4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol to inhibit the common drug met...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C19(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM214688(US9295672, (4-fluorophenyl)(4-((5-methyl-1H-pyraz...)
Affinity DataIC50:  1.47E+4nMT: 2°CAssay Description:The ability of the R and S enantiomers of (4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol to inhibit the common drug met...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 3A4(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM214690(US9295672, (R)-(4-fluorophenyl)(4-((5-methyl-1H-py...)
Affinity DataIC50:  1.48E+4nMT: 2°CAssay Description:The ability of the R and S enantiomers of (4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol to inhibit the common drug met...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM214690(US9295672, (R)-(4-fluorophenyl)(4-((5-methyl-1H-py...)
Affinity DataIC50:  1.52E+4nMT: 2°CAssay Description:The ability of the R and S enantiomers of (4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol to inhibit the common drug met...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C19(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM214689(US9295672, (S)-(4-fluorophenyl)(4-((5-methyl-1H-py...)
Affinity DataIC50:  1.59E+4nMT: 2°CAssay Description:The ability of the R and S enantiomers of (4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol to inhibit the common drug met...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM214688(US9295672, (4-fluorophenyl)(4-((5-methyl-1H-pyraz...)
Affinity DataIC50:  1.74E+4nMT: 2°CAssay Description:The ability of the R and S enantiomers of (4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol to inhibit the common drug met...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C8(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM214689(US9295672, (S)-(4-fluorophenyl)(4-((5-methyl-1H-py...)
Affinity DataIC50:  2.27E+4nMT: 2°CAssay Description:The ability of the R and S enantiomers of (4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol to inhibit the common drug met...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C8(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM214688(US9295672, (4-fluorophenyl)(4-((5-methyl-1H-pyraz...)
Affinity DataIC50:  2.31E+4nMT: 2°CAssay Description:The ability of the R and S enantiomers of (4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol to inhibit the common drug met...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C9(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM214689(US9295672, (S)-(4-fluorophenyl)(4-((5-methyl-1H-py...)
Affinity DataIC50:  2.46E+4nMT: 2°CAssay Description:The ability of the R and S enantiomers of (4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol to inhibit the common drug met...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2C8(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM214690(US9295672, (R)-(4-fluorophenyl)(4-((5-methyl-1H-py...)
Affinity DataIC50:  2.69E+4nMT: 2°CAssay Description:The ability of the R and S enantiomers of (4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol to inhibit the common drug met...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2D6(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM214690(US9295672, (R)-(4-fluorophenyl)(4-((5-methyl-1H-py...)
Affinity DataIC50: >4.00E+4nMT: 2°CAssay Description:The ability of the R and S enantiomers of (4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol to inhibit the common drug met...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2B6(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM214690(US9295672, (R)-(4-fluorophenyl)(4-((5-methyl-1H-py...)
Affinity DataIC50: >4.00E+4nMT: 2°CAssay Description:The ability of the R and S enantiomers of (4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol to inhibit the common drug met...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2D6(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM214689(US9295672, (S)-(4-fluorophenyl)(4-((5-methyl-1H-py...)
Affinity DataIC50: >4.00E+4nMT: 2°CAssay Description:The ability of the R and S enantiomers of (4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol to inhibit the common drug met...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2B6(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM214689(US9295672, (S)-(4-fluorophenyl)(4-((5-methyl-1H-py...)
Affinity DataIC50: >4.00E+4nMT: 2°CAssay Description:The ability of the R and S enantiomers of (4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol to inhibit the common drug met...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2D6(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM214688(US9295672, (4-fluorophenyl)(4-((5-methyl-1H-pyraz...)
Affinity DataIC50: >4.00E+4nMT: 2°CAssay Description:The ability of the R and S enantiomers of (4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol to inhibit the common drug met...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2B6(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM214688(US9295672, (4-fluorophenyl)(4-((5-methyl-1H-pyraz...)
Affinity DataIC50: >4.00E+4nMT: 2°CAssay Description:The ability of the R and S enantiomers of (4-fluorophenyl)(4-((5-methyl-1H-pyrazol-3-yl)amino)quinazolin-2-yl)methanol to inhibit the common drug met...More data for this Ligand-Target Pair
In DepthDetails US Patent