Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for assayid = 1 entry = 9924
TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499668BDBM499668(US11020397, Compound Formula-(IIz))
Affinity DataIC50: 0.0150nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499645BDBM499645(US11020397, Compound Formula-(IIi))
Affinity DataIC50: 0.0200nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499652BDBM499652(US11020397, Compound Formula-(IIl))
Affinity DataIC50: 0.0200nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499646BDBM499646(US11020397, Compound Formula-(IIjj))
Affinity DataIC50: 0.0200nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499675BDBM499675(US11020397, Compound Formula-(IIee))
Affinity DataIC50: 0.0290nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499681BDBM499681(US11020397, Compound Formula-(II5))
Affinity DataIC50: 0.0400nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499657BDBM499657(US11020397, Compound Formula-(IIq))
Affinity DataIC50: 0.0400nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499684BDBM499684(US11020397, Compound Formula-(II8))
Affinity DataIC50: 0.0600nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499680BDBM499680(US11020397, Compound Formula-(II4))
Affinity DataIC50: 0.0600nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499679BDBM499679(US11020397, Compound Formula-(II3))
Affinity DataIC50: 0.0600nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499673BDBM499673(US11020397, Compound Formula-(IIdd))
Affinity DataIC50: 0.0640nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499683BDBM499683(US11020397, Compound Formula-(II7))
Affinity DataIC50: 0.0700nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499664BDBM499664(US11020397, Compound Formula-(IIv))
Affinity DataIC50: 0.100nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499670BDBM499670(US11020397, Compound Formula-(IIaa))
Affinity DataIC50: 0.103nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499659BDBM499659(US11020397, Compound Formula-(IIs))
Affinity DataIC50: 0.120nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499662BDBM499662(US11020397, Compound Formula-(IIt))
Affinity DataIC50: 0.180nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499686BDBM499686(US11020397, Compound Formula-(II10))
Affinity DataIC50: 0.190nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499656BDBM499656(US11020397, Compound Formula-(IIp))
Affinity DataIC50: 0.200nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499671BDBM499671(US11020397, Compound Formula-(IIbb))
Affinity DataIC50: 0.206nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499658BDBM499658(US11020397, Compound Formula-(IIr))
Affinity DataIC50: 0.210nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499687BDBM499687(US11020397, Compound Formula-(II11))
Affinity DataIC50: 0.220nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499651BDBM499651(US11020397, Compound Formula-(IIk))
Affinity DataIC50: 0.280nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499674BDBM499674(US11020397, Compound Formula-(IIkk))
Affinity DataIC50: 0.315nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499667BDBM499667(US11020397, Compound Formula-(IIy))
Affinity DataIC50: 0.330nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499649BDBM499649(US11020397, Compound Formula-(IIii))
Affinity DataIC50: 0.377nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499672BDBM499672(US11020397, Compound Formula-(IIcc))
Affinity DataIC50: 0.519nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499685BDBM499685(US11020397, Compound Formula-(II9))
Affinity DataIC50: 0.520nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499678BDBM499678(US11020397, Compound Formula-(II2))
Affinity DataIC50: 0.530nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499665BDBM499665(US11020397, Compound Formula-(IIw))
Affinity DataIC50: 0.660nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499660BDBM499660(US11020397, Compound Formula-(IIll))
Affinity DataIC50: 1.02nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499655BDBM499655(US11020397, Compound Formula-(IIo))
Affinity DataIC50: 1.14nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499647BDBM499647(US11020397, Compound Formula-(IIgg))
Affinity DataIC50: 1.73nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499661BDBM499661(US11020397, Compound Formula-(IImm))
Affinity DataIC50: 2.86nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499644BDBM499644(US11020397, Compound Formula-(IIff))
Affinity DataIC50: 2.92nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 181133BDBM181133(US9138393, Allopurinol | US9144538, Allopurinol | ...)
Affinity DataIC50: 3.5nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 181133BDBM181133(US9138393, Allopurinol | US9144538, Allopurinol | ...)
Affinity DataIC50: 3.5nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499654BDBM499654(US11020397, Compound Formula-(IIn))
Affinity DataIC50: 3.57nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499663BDBM499663(US11020397, Compound Formula-(IIu))
Affinity DataIC50: 4.30nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499669BDBM499669(US11020397, Compound Formula-(Io))
Affinity DataIC50: 5.30nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499653BDBM499653(US11020397, Compound Formula-(IIm))
Affinity DataIC50: 8.64nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499682BDBM499682(US11020397, Compound Formula-(II6))
Affinity DataIC50: 10nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499648BDBM499648(US11020397, Compound Formula-(IIhh))
Affinity DataIC50: 211nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 37953BDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)
Affinity DataIC50: 300nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 499650BDBM499650(US11020397, Compound Formula-(IIj))
Affinity DataIC50: 300nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent

TargetXanthine dehydrogenase/oxidase(Human)
Acquist

US Patent
LigandChemical structure of BindingDB Monomer ID 37953BDBM37953(US10093631, Compound Lesinurad | US10336710, Lesin...)
Affinity DataIC50: 300nMAssay Description:Xanthine oxidase inhibition was determined using a standard fluorescence-based assay for xanthine oxidase activity (McHale A, Grimes H, Coughlan M P:...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/28/2021
Entry Details
US Patent