Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for assayid = 15 entry = 50006480
TargetNeuropeptide Y receptor type 1(Human)
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)

Curated by ChEMBL
LigandPNGBDBM50246648((R)-1-((5-(4-hydroxybenzylamino)-4-(2,2-diphenylac...)
Affinity DataIC50: 0.120nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 5 mins by Fura-2 dye base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)

Curated by ChEMBL
LigandPNGBDBM50500154(CHEMBL3746870)
Affinity DataIC50: 0.162nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 5 mins by Fura-2 dye base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)

Curated by ChEMBL
LigandPNGBDBM50246649((R)-ethyl 2-(3-((5-(4-hydroxybenzylamino)-4-(2,2-d...)
Affinity DataIC50: 0.170nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 5 mins by Fura-2 dye base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)

Curated by ChEMBL
LigandPNGBDBM50500151(CHEMBL3746386)
Affinity DataIC50: 0.170nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 5 mins by Fura-2 dye base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNeuropeptide Y receptor type 1(Human)
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)

Curated by ChEMBL
LigandPNGBDBM50500153(CHEMBL3746851)
Affinity DataIC50: 0.347nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 5 mins by Fura-2 dye base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetNeuropeptide Y receptor type 1(Human)
Cnrs/Ipbs (Institut De Pharmacologie Et Biologie Structurale)

Curated by ChEMBL
LigandPNGBDBM50060728((R)-5-(diaminomethyleneamino)-2-(2,2-diphenylaceta...)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 5 mins by Fura-2 dye base...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed