Compile Data Set for Download or QSAR
Found 27 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 10662
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557823(1-[4-[6-[5-[[6-(3,3-difluorocyclobutoxy)pyrazin-2-...)
Affinity DataIC50:  49.6nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557820(1-[4-[6-[5-[[6-(cyclobutoxy)pyrazin-2-yl]amino]-1-...)
Affinity DataIC50:  327nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557838(1-[4-[6-[5-[(6-isopropoxypyrazin-2-yl)amino]-1-met...)
Affinity DataIC50:  341nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557829(1-[4-[5-fluoro-6-[5-[(6-isopropoxypyrazin-2-yl)ami...)
Affinity DataIC50:  495nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557831(1-[4-[6-[5-[[6-(1-fluoro-1-methyl-ethyl)pyrazin-2-...)
Affinity DataIC50:  804nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557825(1-[4-[6-[5-[(6-isopropoxypyrazin-2-yl)amino]-1-met...)
Affinity DataIC50:  1.05E+3nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557840(US11365185, Example 22B)
Affinity DataIC50:  1.17E+3nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557770(1-[4-[6-[5-[(6-tert-butoxypyrazin-2-yl)amino]-1-me...)
Affinity DataIC50:  1.33E+3nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557822(1-[4-[5-fluoro-6-[5-[[6-(1-fluoro-1-methyl-ethyl)p...)
Affinity DataIC50:  1.59E+3nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557839(1-[4-[6-[1-methyl-5-[[6-(trifluoromethyl)pyrazin-2...)
Affinity DataIC50:  1.61E+3nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557835(US11365185, Example 17B)
Affinity DataIC50:  1.83E+3nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557845(US11365185, Example 27B)
Affinity DataIC50:  1.98E+3nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557836(1-[4-[2-[5-[(6-isopropylpyrazin-2-yl)amino]-1-meth...)
Affinity DataIC50:  2.36E+3nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557837(1-[4-[5-[5-[(6-isopropylpyrazin-2-yl)amino]-1-meth...)
Affinity DataIC50:  2.40E+3nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557821(1-[4-[6-[5-[[6-(cyclopropoxy)pyrazin-2-yl]amino]-1...)
Affinity DataIC50:  2.48E+3nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557842(US11365185, Example 24B)
Affinity DataIC50:  2.76E+3nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557830(1-[4-[6-[5-[[6-(1,1-difluoroethyl)pyrazin-2-yl]ami...)
Affinity DataIC50:  4.28E+3nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557828(1-[4-[6-[5-[[6-(cyclopropoxy)pyrazin-2-yl]amino]-1...)
Affinity DataIC50:  4.42E+3nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557834(1-[3-cyano-4-[6-[5-[(6-isopropylpyrazin-2-yl)amino...)
Affinity DataIC50:  4.62E+3nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557824(1-[4-[6-[5-[[6-(1-methoxy-1-methyl-ethyl)pyrazin-2...)
Affinity DataIC50:  5.27E+3nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557844(1-[4-[4-[5-[(6-isopropylpyrazin-2-yl)amino]-1-meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557843(US11365185, Example 25B)
Affinity DataIC50: >1.00E+4nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557841(US11365185, Example 23B)
Affinity DataIC50: >1.00E+4nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557833(1-[3-(cyanomethyl)-4-[6-[5-[(6-isopropylpyrazin-2-...)
Affinity DataIC50: >1.00E+4nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557827(1-[2-cyano-4-[6-[5-[[6-(cyclopropoxy)pyrazin-2-yl]...)
Affinity DataIC50: >1.00E+4nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557826(1-[4-[6-[5-[[6-(cyclopropoxy)pyrazin-2-yl]amino]-1...)
Affinity DataIC50: >1.00E+4nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetLysophosphatidic acid receptor 3(Homo sapiens (Human))
Eli Lilly and Company

US Patent
LigandPNGBDBM557832(1-[4-[6-[5-[(6-isopropylpyrazin-2-yl)amino]-1-meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:A cDNA encoding the human LPAR3 receptor is synthesized and cloned into pDNA3 expression plasmid. The plasmid is transfected in U2OS cells using Lipo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent