Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 2781
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Eberhard Karls University Tuebingen

LigandPNGBDBM22334(N-(3-phenoxycinnamyl)acetohydroxamic acid | BW A4C...)
Affinity DataIC50: 200nMpH: 7.4 T: 2°CAssay Description:For determination of the activity of 5-LO in 100000g supernatants, aliquots of the supernatants were added to reaction mix, and were preincubated wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Eberhard Karls University Tuebingen

LigandPNGBDBM24561(ethyl 2-{[4-chloro-6-(quinolin-6-ylamino)pyrimidin...)
Affinity DataIC50: 1.90E+4nM EC50:  600nMpH: 7.4 T: 2°CAssay Description:For determination of the activity of 5-LO in 100000g supernatants, aliquots of the supernatants were added to reaction mix, and were preincubated wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Eberhard Karls University Tuebingen

LigandPNGBDBM24565(CHEMBL518643 | 2-({4-chloro-6-[(quinolin-6-ylmethy...)
Affinity DataIC50: 3.10E+4nMpH: 7.4 T: 2°CAssay Description:For determination of the activity of 5-LO in 100000g supernatants, aliquots of the supernatants were added to reaction mix, and were preincubated wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Eberhard Karls University Tuebingen

LigandPNGBDBM24564(2-{[4-chloro-6-(quinolin-6-ylamino)pyrimidin-2-yl]...)
Affinity DataIC50: 3.40E+4nMpH: 7.4 T: 2°CAssay Description:For determination of the activity of 5-LO in 100000g supernatants, aliquots of the supernatants were added to reaction mix, and were preincubated wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2008
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Eberhard Karls University Tuebingen

LigandPNGBDBM24563(ethyl 2-({4-chloro-6-[(quinolin-6-ylmethyl)amino]p...)
Affinity DataIC50: 3.70E+4nM EC50:  1.40E+3nMpH: 7.4 T: 2°CAssay Description:For determination of the activity of 5-LO in 100000g supernatants, aliquots of the supernatants were added to reaction mix, and were preincubated wit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2008
Entry Details Article
PubMed