Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50013135
TargetGlycogen synthase kinase-3 beta(Human)
University of Central Lancashire

Curated by ChEMBL
LigandPNGBDBM92353(Sorafenib derivative, 16)
Affinity DataIC50: 860nMAssay Description:Inhibition of human GSK-3beta using Ser/Thr 6 peptide as substrate preincubated for 60 mins followed by ATP and substrate addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Central Lancashire

Curated by ChEMBL
LigandPNGBDBM92354(Sorafenib derivative, 17)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human GSK-3beta using Ser/Thr 6 peptide as substrate preincubated for 60 mins followed by ATP and substrate addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Central Lancashire

Curated by ChEMBL
LigandPNGBDBM16673(Xarelto | BAY439006 | CHEMBL1336 | BAY 43-9006 | 4...)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of human GSK-3beta using Ser/Thr 6 peptide as substrate preincubated for 60 mins followed by ATP and substrate addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Central Lancashire

Curated by ChEMBL
LigandPNGBDBM13533(1-[5-tert-butyl-2-(p-tolyl)pyrazol-3-yl]-3-[4-(2-m...)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of human GSK-3beta using Ser/Thr 6 peptide as substrate preincubated for 60 mins followed by ATP and substrate addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Central Lancashire

Curated by ChEMBL
LigandPNGBDBM92352(BIRB-796 derivative, 12)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human GSK-3beta using Ser/Thr 6 peptide as substrate preincubated for 60 mins followed by ATP and substrate addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Central Lancashire

Curated by ChEMBL
LigandPNGBDBM14847(3-[1-(3-aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl]...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human GSK-3beta using Ser/Thr 6 peptide as substrate preincubated for 60 mins followed by ATP and substrate addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Central Lancashire

Curated by ChEMBL
LigandPNGBDBM50115209(CHEMBL101035 | 1-(5-tert-Butyl-2-p-tolyl-2H-pyrazo...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human GSK-3beta using Ser/Thr 6 peptide as substrate preincubated for 60 mins followed by ATP and substrate addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Central Lancashire

Curated by ChEMBL
LigandPNGBDBM31824(1-(1-(3-Aminophenyl)-3-tert-butyl-1H-pyrazol-5-yl)...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human GSK-3beta using Ser/Thr 6 peptide as substrate preincubated for 60 mins followed by ATP and substrate addition and measured after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2022
Entry Details Article
PubMed