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Report error Found 11 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50017020
TargetReplicase polyprotein 1ab(HCoV-229E)
Experimental Drug Development Centre

Curated by ChEMBL
LigandPNGBDBM50599200(CHEMBL5182995 | US11753373, Compound D-1-c)
Affinity DataIC50:  13nMAssay Description:Inhibition of full length C terminal His-tagged Human coronavirus 229E 3CLpro expressed in Escherichia coli Rosetta (DE3) cells using (DABCYL)KTSAVLQ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetReplicase polyprotein 1ab(HCoV-229E)
Experimental Drug Development Centre

Curated by ChEMBL
LigandPNGBDBM50599197(CHEMBL5173582 | US11753373, Compound D-1-f)
Affinity DataIC50:  16nMAssay Description:Inhibition of full length C terminal His-tagged Human coronavirus 229E 3CLpro expressed in Escherichia coli Rosetta (DE3) cells using (DABCYL)KTSAVLQ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(HCoV-229E)
Experimental Drug Development Centre

Curated by ChEMBL
LigandPNGBDBM50599203(CHEMBL5183165)
Affinity DataIC50:  70nMAssay Description:Inhibition of full length C terminal His-tagged Human coronavirus 229E 3CLpro expressed in Escherichia coli Rosetta (DE3) cells using (DABCYL)KTSAVLQ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(HCoV-229E)
Experimental Drug Development Centre

Curated by ChEMBL
LigandPNGBDBM496902(CVD-0018409 | PF-07321332 | US11351149, Example 13...)
Affinity DataIC50:  145nMAssay Description:Inhibition of full length C terminal His-tagged Human coronavirus 229E 3CLpro expressed in Escherichia coli Rosetta (DE3) cells using (DABCYL)KTSAVLQ...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(HCoV-229E)
Experimental Drug Development Centre

Curated by ChEMBL
LigandPNGBDBM535146(WO2022013684, Example 13)
Affinity DataIC50:  239nMAssay Description:Inhibition of full length C terminal His-tagged Human coronavirus 229E 3CLpro expressed in Escherichia coli Rosetta (DE3) cells using (DABCYL)KTSAVLQ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(HCoV-229E)
Experimental Drug Development Centre

Curated by ChEMBL
LigandPNGBDBM50599202(CHEMBL5173858)
Affinity DataIC50:  290nMAssay Description:Inhibition of full length C terminal His-tagged Human coronavirus 229E 3CLpro expressed in Escherichia coli Rosetta (DE3) cells using (DABCYL)KTSAVLQ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(HCoV-229E)
Experimental Drug Development Centre

Curated by ChEMBL
LigandPNGBDBM50599204(CHEMBL5174632)
Affinity DataIC50:  467nMAssay Description:Inhibition of full length C terminal His-tagged Human coronavirus 229E 3CLpro expressed in Escherichia coli Rosetta (DE3) cells using (DABCYL)KTSAVLQ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(HCoV-229E)
Experimental Drug Development Centre

Curated by ChEMBL
LigandPNGBDBM50599198(CHEMBL5207993)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full length C terminal His-tagged Human coronavirus 229E 3CLpro expressed in Escherichia coli Rosetta (DE3) cells using (DABCYL)KTSAVLQ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(HCoV-229E)
Experimental Drug Development Centre

Curated by ChEMBL
LigandPNGBDBM50599201(CHEMBL5208243)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full length C terminal His-tagged Human coronavirus 229E 3CLpro expressed in Escherichia coli Rosetta (DE3) cells using (DABCYL)KTSAVLQ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(HCoV-229E)
Experimental Drug Development Centre

Curated by ChEMBL
LigandPNGBDBM50599196(CHEMBL5199404)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full length C terminal His-tagged Human coronavirus 229E 3CLpro expressed in Escherichia coli Rosetta (DE3) cells using (DABCYL)KTSAVLQ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetReplicase polyprotein 1ab(HCoV-229E)
Experimental Drug Development Centre

Curated by ChEMBL
LigandPNGBDBM50599199(CHEMBL5178853)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of full length C terminal His-tagged Human coronavirus 229E 3CLpro expressed in Escherichia coli Rosetta (DE3) cells using (DABCYL)KTSAVLQ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed