Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) with all data for assayid = 2 entry = 7827
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Georgetown University

US Patent
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataEC50:  2.40E+3nMAssay Description:The functional properties of the ligands were determined by 86Rb+ efflux assays in cells expressing α3β4 and α4β2 nAChR subtypes....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Georgetown University

US Patent
LigandPNGBDBM221048(US9303017, Varenicline | US9284322, varenicline)
Affinity DataEC50:  950nMAssay Description:The functional properties of the ligands were determined by 86Rb+ efflux assays in cells expressing α3β4 and α4β2 nAChR subtypes....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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PDB3D3D Structure (crystal)
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Georgetown University

US Patent
LigandPNGBDBM50382474(CHEMBL2024096 | US9303017, Sazetidine-A)
Affinity DataEC50:  24nMAssay Description:The functional properties of the ligands were determined by 86Rb+ efflux assays in cells expressing α3β4 and α4β2 nAChR subtypes....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Georgetown University

US Patent
LigandPNGBDBM50428085(CHEMBL2323566 | US9303017, (S)-15, YL-1-127)
Affinity DataEC50:  310nMAssay Description:The functional properties of the ligands were determined by 86Rb+ efflux assays in cells expressing α3β4 and α4β2 nAChR subtypes....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Georgetown University

US Patent
LigandPNGBDBM50428079(CHEMBL2323569 | US9303017, 25, YL-1-199)
Affinity DataEC50:  160nMAssay Description:The functional properties of the ligands were determined by 86Rb+ efflux assays in cells expressing α3β4 and α4β2 nAChR subtypes....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
Georgetown University

US Patent
LigandPNGBDBM50428081(CHEMBL2323570 | US9303017, (S)-17)
Affinity DataEC50:  63nMAssay Description:The functional properties of the ligands were determined by 86Rb+ efflux assays in cells expressing α3β4 and α4β2 nAChR subtypes....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rat)
Georgetown University

US Patent
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataEC50:  2.30E+4nMAssay Description:The functional properties of the ligands were determined by 86Rb+ efflux assays in cells expressing α3β4 and α4β2 nAChR subtypes....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rat)
Georgetown University

US Patent
LigandPNGBDBM221048(US9303017, Varenicline | US9284322, varenicline)
Affinity DataEC50:  2.20E+4nMAssay Description:The functional properties of the ligands were determined by 86Rb+ efflux assays in cells expressing α3β4 and α4β2 nAChR subtypes....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
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TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rat)
Georgetown University

US Patent
LigandPNGBDBM50382474(CHEMBL2024096 | US9303017, Sazetidine-A)
Affinity DataEC50:  2.40E+4nMAssay Description:The functional properties of the ligands were determined by 86Rb+ efflux assays in cells expressing α3β4 and α4β2 nAChR subtypes....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/10/2017
Entry Details
Go to US Patent