Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for assayid = 3 entry = 50038940
Target5-hydroxytryptamine receptor 3A(Rat)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50060685BDBM50060685(9-fluoro-4-(4-methylpiperazin-1-yl)pyrrolo[1,2-a]q...)
Affinity DataKi:  0.440nMAssay Description:Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299661BDBM50299661(9-methyl-4-(4-((3H-imidazol-4-yl)methyl)piperazin-...)
Affinity DataKi:  0.490nMAssay Description:Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299660BDBM50299660(7-fluoro-4-(4-((3H-imidazol-4-yl)methyl)piperazin-...)
Affinity DataKi:  0.680nMAssay Description:Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50081969BDBM50081969(9-Methyl-4-(4-methyl-piperazin-1-yl)-pyrrolo[1,2-a...)
Affinity DataKi:  0.790nMAssay Description:Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50060688BDBM50060688(7-Fluoro-4-(4-methyl-piperazin-1-yl)-pyrrolo[1,2-a...)
Affinity DataKi:  0.810nMAssay Description:Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014407BDBM50014407(2-Piperazin-1-yl-quinoline (Quipazine) | CHEMBL187...)
Affinity DataKi:  0.960nMAssay Description:Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50081968BDBM50081968(6-(4-benzylpiperazin-1-yl)pyrido[2,3-e]pyrrolo[1,2...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299665BDBM50299665(7-hydroxy-4-(4-((3H-imidazol-4-yl)methyl)piperazin...)
Affinity DataKi:  2.25nMAssay Description:Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50081970BDBM50081970(6-(4-Methyl-piperazin-1-yl)-pyrido[2,3-e]pyrrolo[1...)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299662BDBM50299662(7-fluoro-4-(4-((1H-imidazol-2-yl)methyl)piperazin-...)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50081981BDBM50081981(4-(4-Benzyl-piperazin-1-yl)-9-methyl-pyrrolo[1,2-a...)
Affinity DataIC50: 8.80nMAssay Description:Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50258292BDBM50258292(2-(4-(7-fluoropyrrolo[1,2-a]quinoxalin-4-yl)pipera...)
Affinity DataKi:  11.7nMAssay Description:Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50081974BDBM50081974(4-(4-Benzyl-piperazin-1-yl)-7-fluoro-pyrrolo[1,2-a...)
Affinity DataIC50: 13nMAssay Description:Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299664BDBM50299664(9-methyl-4-(4-(2-(1H-imidazol-1-yl)ethyl)piperazin...)
Affinity DataKi:  17.8nMAssay Description:Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299663BDBM50299663(7-fluoro-4-(4-(2-(1H-imidazol-1-yl)ethyl)piperazin...)
Affinity DataKi:  22.2nMAssay Description:Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299667BDBM50299667(7-fluoro-4-(4-((4,5-dihydro-1H-imidazol-2-yl)methy...)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299668BDBM50299668((4-(7-fluoropyrrolo[1,2-a]quinoxalin-4-yl)piperazi...)
Affinity DataKi:  44.3nMAssay Description:Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Rat)
European Research Centre For Drug Discovery and Development (Natsyndrugs)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50299666BDBM50299666(7-fluoro-4-(4-(2-(1H-imidazol-4-yl)ethyl)piperazin...)
Affinity DataKi:  330nMAssay Description:Displacement of [3H]LY278584 from 5HT3 receptor in rat cortical homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/26/2012
Entry Details Article
PubMed