Compile Data Set for Download or QSAR
maximum 50k data
Found 67 Enz. Inhib. hit(s) with all data for assayid = 3 entry = 7924
LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50:  20nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50:  50nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
TargetTyrosine-protein kinase ABL1 [64-515](Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetActivin receptor type-1 [172-499](Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 2 [406-821](Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFibroblast growth factor receptor 4 [388-802](Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3 [563-993,D835Y](Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 1 [184-712](Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2 [808-1132](Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2 [807-1356](Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase 8 [30-404](Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase kinase kinase kinase 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha [551-1089,V561D](Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 2 [6-553](Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase 17B(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase 4(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase SYK [2-635](Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ZAP-70(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >3.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >3.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >3.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >3.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >3.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >3.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >3.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >3.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >3.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >3.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >3.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >3.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >3.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >3.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >3.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >3.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >3.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >3.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >3.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >3.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >3.00E+4nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA (cytosine-5)-methyltransferase 1(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+5nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+5nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 8(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+5nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Homo sapiens (Human))
Novartis Institutes For Biomedical Research

LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50: >1.00E+5nMAssay Description:All HMT reactions were performed as described previously [Nasveschuk et al., ACS Med. Chem. Lett., 5:378-383].More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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