Compile Data Set for Download or QSAR
Found 119 Enz. Inhib. hit(s) with all data for assayid = 4 entry = 1937
TargetGlycogen synthase kinase-3 alpha(Homo sapiens (Human))
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LigandPNGBDBM256527(US10435361, Example 26 | US9481648, 26 | US9790174...)
Affinity DataIC50:  51nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256545(US10435361, Example 44 | US9481648, 44 | US9790174...)
Affinity DataIC50:  80nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256532(US10435361, Example 31 | US9481648, 31 | US9790174...)
Affinity DataIC50:  135nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256531(US10435361, Example 30 | US9481648, 30 | US9790174...)
Affinity DataIC50:  150nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256583(US10435361, Example 82 | US9481648, 82 | US9790174...)
Affinity DataIC50:  182nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256614(US10435361, Example 85(q) | US9481648, 85(q) | US9...)
Affinity DataIC50:  249nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM256603(US10435361, Example 85(e) | US9481648, 85(e) | US9...)
Affinity DataIC50:  300nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM256562(US10435361, Example 61 | US9481648, 61 | US9790174...)
Affinity DataIC50:  372nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM347499(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(methylsu...)
Affinity DataIC50:  379nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM256604(US10435361, Example 85(f) | US9481648, 85(f) | US9...)
Affinity DataIC50:  390nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM142019(US10435361, Example 16 | US8927563, I | US9481648,...)
Affinity DataIC50:  411nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256605(US10435361, Example 85(g) | US9481648, 85(g) | US9...)
Affinity DataIC50:  437nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256542(US10435361, Example 41 | US9481648, 41 | US9790174...)
Affinity DataIC50:  446nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM347466(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(methylsu...)
Affinity DataIC50:  516nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256544(US10435361, Example 43 | US9481648, 43 | US9790174...)
Affinity DataIC50:  520nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256561(US10435361, Example 60 | US9481648, 60 | US9790174...)
Affinity DataIC50:  539nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM347465(3-((4-((4-(3-(5-(tert-Butyl)-2-methoxy-3-(methylsu...)
Affinity DataIC50:  541nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256536(US10435361, Example 35 | US9481648, 35 | US9790174...)
Affinity DataIC50:  597nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
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LigandPNGBDBM256533(US10435361, Example 32 | US9481648, 32 | US9790174...)
Affinity DataIC50:  629nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256547(US10435361, Example 46 | US9481648, 46 | US9790174...)
Affinity DataIC50:  636nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256503(US9481648, 1 | US9790174, Example 1)
Affinity DataIC50:  657nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256525(US10435361, Example 24 | US9481648, 24 | US9790174...)
Affinity DataIC50:  680nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256543(US10435361, Example 42 | US9481648, 42 | US9790174...)
Affinity DataIC50:  705nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256524(US10435361, Example 23 | US9481648, 23 | US9790174...)
Affinity DataIC50:  733nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256607(US10435361, Example 85(i) | US9481648, 85(i) | US9...)
Affinity DataIC50:  736nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256586(US10435361, Example 83(c) | US9481648, 83(c) | US9...)
Affinity DataIC50:  738nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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LigandPNGBDBM256521(US10435361, Example 20 | US9481648, 20 | US9790174...)
Affinity DataIC50:  748nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256557(US10435361, Example 56 | US9481648, 56 | US9790174...)
Affinity DataIC50:  763nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256618(US10435361, Example 85(w) | US9481648, 85(w) | US9...)
Affinity DataIC50:  769nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256515(US10435361, Example 13 | US9481648, 13 | US9790174...)
Affinity DataIC50:  824nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256534(US10435361, Example 33 | US9481648, 33 | US9790174...)
Affinity DataIC50:  828nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256564(US10435361, Example 63 | US9481648, 63 | US9790174...)
Affinity DataIC50:  829nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256619(US10435361, Example 85(x) | US9481648, 85(x) | US9...)
Affinity DataIC50:  878nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256579(US10435361, Example 78 | US9481648, 78 | US9790174...)
Affinity DataIC50:  896nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256517(US10435361, Example 15 | US9481648, 15 | US9790174...)
Affinity DataIC50:  905nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256552(US10435361, Example 51 | US9481648, 51 | US9790174...)
Affinity DataIC50:  977nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256560(US10435361, Example 59 | US9481648, 59 | US9790174...)
Affinity DataIC50:  978nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256516(US10435361, Example 14 | US9481648, 14 | US9790174...)
Affinity DataIC50:  1.01E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256587(US10435361, Example 83(d) | US9481648, 83(d) | US9...)
Affinity DataIC50:  1.02E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256558(US10435361, Example 57 | US9481648, 57 | US9790174...)
Affinity DataIC50:  1.13E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256613(US10435361, Example 85(p) | US9481648, 85(p) | US9...)
Affinity DataIC50:  1.16E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256581(US10435361, Example 80 | US9481648, 80 | US9790174...)
Affinity DataIC50:  1.25E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM347469(N-(5-(tert-Butyl)-3-(3-(2,3-dichloro-4-((2-((3-met...)
Affinity DataIC50:  1.31E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256565(US10435361, Example 64 | US9481648, 64 | US9790174...)
Affinity DataIC50:  1.46E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256538(US10435361, Example 37 | US9481648, 37 | US9790174...)
Affinity DataIC50:  1.52E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256570(US10435361, Example 69 | US9481648, 69 | US9790174...)
Affinity DataIC50:  1.53E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256588(US10435361, Example 83(e) | US9481648, 83(e) | US9...)
Affinity DataIC50:  1.59E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256540(US10435361, Example 39 | US9481648, 39 | US9790174...)
Affinity DataIC50:  1.60E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256548(US10435361, Example 47 | US9481648, 47 | US9790174...)
Affinity DataIC50:  1.60E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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LigandPNGBDBM256511(US10435361, Example 9 | US9481648, 9 | US9790174, ...)
Affinity DataIC50:  1.63E+3nMAssay Description:The inhibitory activities of compounds of the invention against the GSK 3α enzyme isoform (Invitrogen), are evaluated by determining the level o...More data for this Ligand-Target Pair
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