Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for assayid = 4 entry = 50008717
TargetProstaglandin E2 receptor EP2 subtype(Human)
Cayman Chemical

Curated by ChEMBL
LigandPNGBDBM35847(DINOPROSTONE | [3H]Prostaglandin E2 | prostaglandi...)
Affinity DataEC50:  9.30nMAssay Description:Agonist activity at human EP2 receptor expressed in HEK293T/17 cells assessed as increase in GalphaS-mediated CREB activation measured after 6 to 24 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Cayman Chemical

Curated by ChEMBL
LigandPNGBDBM50101858(4-(2-((1R,2R,3R)-3-hydroxy-2-((S,E)-3-hydroxy-4-(3...)
Affinity DataEC50:  610nMAssay Description:Agonist activity at human EP2 receptor expressed in HEK293T/17 cells assessed as increase in GalphaS-mediated CREB activation measured after 6 to 24 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Cayman Chemical

Curated by ChEMBL
LigandPNGBDBM190270(US9180116, 9C)
Affinity DataEC50:  2.27E+3nMAssay Description:Agonist activity at human EP2 receptor expressed in HEK293T/17 cells assessed as increase in GalphaS-mediated CREB activation measured after 6 to 24 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Cayman Chemical

Curated by ChEMBL
LigandPNGBDBM190268(US9180116, 2C)
Affinity DataEC50:  7.36E+3nMAssay Description:Agonist activity at human EP2 receptor expressed in HEK293T/17 cells assessed as increase in GalphaS-mediated CREB activation measured after 6 to 24 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Cayman Chemical

Curated by ChEMBL
LigandPNGBDBM50521600(CHEMBL4558749)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human EP2 receptor expressed in HEK293T/17 cells assessed as increase in GalphaS-mediated CREB activation measured after 6 to 24 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Human)
Cayman Chemical

Curated by ChEMBL
LigandPNGBDBM50142481(8-aza-11-deoxyprostaglandin E1 | 7-[(R)-2-((E)-(S)...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human EP2 receptor expressed in HEK293T/17 cells assessed as increase in GalphaS-mediated CREB activation measured after 6 to 24 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed