Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for assayid = 4 entry = 50031037
TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50305735BDBM50305735(N,N'-(1,2-phenylene)bis(N-methyl-1-phenylmethanesu...)
Affinity DataIC50: 6.70nMAssay Description:Antagonist activity at C5a receptor in human PMNC assessed as inhibition of anaphylatoxin C5a-induced intracellular calcium accumulation after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50305737BDBM50305737(N,N'-(1,2-phenylene)bis(N-allyl-4-methylbenzenesul...)
Affinity DataIC50: 59nMAssay Description:Antagonist activity at C5a receptor in human PMNC assessed as inhibition of anaphylatoxin C5a-induced intracellular calcium accumulation after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50305731BDBM50305731(N,4-dimethyl-N-(2-(thiophene-3-carbonyl)phenyl)ben...)
Affinity DataIC50: 400nMAssay Description:Antagonist activity at C5a receptor in human PMNC assessed as inhibition of anaphylatoxin C5a-induced intracellular calcium accumulation after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50305741BDBM50305741(1,4-ditosylpiperazine | CHEMBL596080)
Affinity DataIC50: 6.00E+4nMAssay Description:Antagonist activity at C5a receptor in human PMNC assessed as inhibition of anaphylatoxin C5a-induced intracellular calcium accumulation after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed
TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Wyeth Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50305742BDBM50305742(N,N'-(propane-1,3-diyl)bis(4-methyl-N-phenylbenzen...)
Affinity DataIC50: 6.00E+4nMAssay Description:Antagonist activity at C5a receptor in human PMNC assessed as inhibition of anaphylatoxin C5a-induced intracellular calcium accumulation after 10 min...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2010
Entry Details Article
PubMed