Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for assayid = 5 entry = 50031201
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50308905(3-[2-({[3-Methyl-1-(1-naphthyl)butyl]amino}carbony...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50308906(3-[2-({[(1R)-1-(1-Naphthyl)ethyl]amino}carbonyl)-4...)
Affinity DataIC50: 39nMAssay Description:Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50307409(3-(2-(3-methyl-1-phenylbutylcarbamoyl)-4-(phenoxym...)
Affinity DataIC50: 68nMAssay Description:Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50308911(3-(4-(Phenoxymethyl)-2-{[(1-phenylbutyl)amino]carb...)
Affinity DataIC50: 240nMAssay Description:Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50308912(3-[2-{[(2-Cyclopropyl-1-phenylethyl)amino]carbonyl...)
Affinity DataIC50: 260nMAssay Description:Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50308915(3-[2-{[(1-Naphthylmethyl)amino]carbonyl}-4-(1Hpyra...)
Affinity DataIC50: 520nMAssay Description:Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50308910(3-(4-(Phenoxymethyl)-2-{[(1-phenylpropyl)amino]car...)
Affinity DataIC50: 520nMAssay Description:Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM35861(phenylpropanoic acid analogue, 5)
Affinity DataIC50: 580nMAssay Description:Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50308902(3-[2-{[(1-Naphthylmethyl)amino]carbonyl}-4-(phenox...)
Affinity DataIC50: 770nMAssay Description:Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50308904(3-[2-{[(1-Benzyl-3-methylbutyl)amino]carbonyl}-4-(...)
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50308914(3-[2-[(Benzhydrylamino)carbonyl]-4-(phenoxymethyl)...)
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50308909(3-(4-(Phenoxymethyl)-2-{[(1-phenylethyl)amino]carb...)
Affinity DataIC50: 2.20E+3nMAssay Description:Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50308913(3-[2-{[(3-Hydroxy-3-methyl-1-phenylbutyl)amino]car...)
Affinity DataIC50: 2.70E+3nMAssay Description:Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50308907(3-[2-({[(1S)-1-(1-Naphthyl)ethyl]amino}carbonyl)-4...)
Affinity DataIC50: 9.50E+3nMAssay Description:Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50308908(3-[2-[(Benzylamino)carbonyl]-4-(phenoxymethyl)phen...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50308903(3-(4-(Phenoxymethyl)-2-{[(2-phenylethyl)amino]carb...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at mouse EP3alpha receptor expressed in CHO cells assessed as inhibition of PGE2-induced increase in intracellular calcium level ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2010
Entry Details Article
PubMed