Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for assayid = 6 entry = 50011638
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82070BDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataKi:  234nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membranes preincubated for 5 mins followed by [125I]alpha-bungarotoxin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357064BDBM50357064(CHEMBL1917231)
Affinity DataKi:  430nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membranes preincubated for 5 mins followed by [125I]alpha-bungarotoxin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50549600BDBM50549600(CHEMBL4755768)
Affinity DataKi:  2.10E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membranes preincubated for 5 mins followed by [125I]alpha-bungarotoxin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50549596BDBM50549596(CHEMBL4785648)
Affinity DataKi:  2.60E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membranes preincubated for 5 mins followed by [125I]alpha-bungarotoxin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50549601BDBM50549601(CHEMBL4762584)
Affinity DataKi:  8.10E+3nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membranes preincubated for 5 mins followed by [125I]alpha-bungarotoxin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50549608BDBM50549608(CHEMBL4799765)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membranes preincubated for 5 mins followed by [125I]alpha-bungarotoxin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50549607BDBM50549607(CHEMBL4760797)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membranes preincubated for 5 mins followed by [125I]alpha-bungarotoxin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50549606BDBM50549606(CHEMBL4762415)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membranes preincubated for 5 mins followed by [125I]alpha-bungarotoxin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50549610BDBM50549610(CHEMBL4792797)
Affinity DataKi:  1.04E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membranes preincubated for 5 mins followed by [125I]alpha-bungarotoxin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50549602BDBM50549602(CHEMBL4798883)
Affinity DataKi:  1.05E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membranes preincubated for 5 mins followed by [125I]alpha-bungarotoxin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50549604BDBM50549604(CHEMBL4744398)
Affinity DataKi:  1.35E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membranes preincubated for 5 mins followed by [125I]alpha-bungarotoxin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50549611BDBM50549611(CHEMBL4758050)
Affinity DataKi:  1.91E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membranes preincubated for 5 mins followed by [125I]alpha-bungarotoxin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357065BDBM50357065(CHEMBL1917232)
Affinity DataKi:  2.00E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membranes preincubated for 5 mins followed by [125I]alpha-bungarotoxin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50194315BDBM50194315((S)-2-((R)-2,3-dihydrobenzo[b][1,4]dioxin-2-yl)-1-...)
Affinity DataKi:  2.10E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membranes preincubated for 5 mins followed by [125I]alpha-bungarotoxin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50549603BDBM50549603(CHEMBL4778976)
Affinity DataKi:  2.68E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membranes preincubated for 5 mins followed by [125I]alpha-bungarotoxin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50549605BDBM50549605(CHEMBL4783660)
Affinity DataKi:  3.15E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membranes preincubated for 5 mins followed by [125I]alpha-bungarotoxin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357062BDBM50357062(CHEMBL1917229)
Affinity DataKi:  3.60E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membranes preincubated for 5 mins followed by [125I]alpha-bungarotoxin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50549609BDBM50549609(CHEMBL4792229)
Affinity DataKi:  4.22E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membranes preincubated for 5 mins followed by [125I]alpha-bungarotoxin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50549595BDBM50549595(CHEMBL4741357)
Affinity DataKi:  4.45E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membranes preincubated for 5 mins followed by [125I]alpha-bungarotoxin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50549598BDBM50549598(CHEMBL4747289)
Affinity DataKi:  4.55E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membranes preincubated for 5 mins followed by [125I]alpha-bungarotoxin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50549597BDBM50549597(CHEMBL4784011)
Affinity DataKi:  5.00E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membranes preincubated for 5 mins followed by [125I]alpha-bungarotoxin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50357063BDBM50357063(CHEMBL1917230)
Affinity DataKi:  5.10E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membranes preincubated for 5 mins followed by [125I]alpha-bungarotoxin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259713BDBM50259713(CHEMBL4095303)
Affinity DataKi:  8.90E+4nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membranes preincubated for 5 mins followed by [125I]alpha-bungarotoxin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
University of Milan

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50549599BDBM50549599(CHEMBL4783337)
Affinity DataKi:  1.09E+5nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7nAChR in rat hippocampus membranes preincubated for 5 mins followed by [125I]alpha-bungarotoxin a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed