Compile Data Set for Download or QSAR
maximum 50k data
Found 35 of ph data with Target = '5-hydroxytryptamine receptor 2B'
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM50395587(CHEMBL2165126 | UNC10000006 | US9156822, 2)
Affinity DataKi:  0.600nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM50395569(CHEMBL2165119 | UNC10099975 | US9156822, 3 or UNC9...)
Affinity DataKi:  1.10nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)
Affinity DataKi:  1.40nMpH: 7.4Assay Description:Membranes prepared as above were resuspended to 1 ug protein/ul (measured by Bradford assay using BSA as standard), and 50 ul were added to each well...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM28579(1-sulfonylindazole, 7a | N-[1-(naphthalene-1-sulfo...)
Affinity DataKi:  130nM ΔG°:  -38.9kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM28574(1-sulfonylindazole, 6c | 3-amino-N-[1-(naphthalene...)
Affinity DataKi:  155nM ΔG°:  -38.5kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM28580(1-sulfonylindazole, 7b | N-[1-(naphthalene-1-sulfo...)
Affinity DataKi:  174nM ΔG°:  -38.2kJ/molepH: 7.4 T: 2°CAssay Description:Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
University Of Dundee

US Patent
LigandPNGBDBM186963(US9079895, 65)
Affinity DataKi:  333nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
University Of Dundee

US Patent
LigandPNGBDBM186962(US9079895, 64)
Affinity DataKi:  441nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM21358(2-[1-({6-chloroimidazo[2,1-b][1,3]thiazole-5-}sulf...)
Affinity DataKi:  458nM ΔG°:  -35.8kJ/molepH: 7.4 T: 2°CAssay Description:IC50 values for each test compound were determined from nonlinear regression analysis of data collected from ligand binding experiments. The inhibiti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
University Of Dundee

US Patent
LigandPNGBDBM186935(US9079895, 23s)
Affinity DataKi:  551nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
University Of Dundee

US Patent
LigandPNGBDBM186923(US9079895, 15r)
Affinity DataKi:  600nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
University Of Dundee

US Patent
LigandPNGBDBM186937(US9079895, 25s)
Affinity DataKi:  658nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
University Of Dundee

US Patent
LigandPNGBDBM186964(US9079895, 66)
Affinity DataKi:  770nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
University Of Dundee

US Patent
LigandPNGBDBM186925(US9079895, 17r)
Affinity DataKi:  788nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
University Of Dundee

US Patent
LigandPNGBDBM186934(US9079895, 22s)
Affinity DataKi:  1.10E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
University Of Dundee

US Patent
LigandPNGBDBM186945(US9079895, 29r)
Affinity DataKi:  1.33E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
University Of Dundee

US Patent
LigandPNGBDBM186927(US9079895, 19s)
Affinity DataKi:  1.45E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
University Of Dundee

US Patent
LigandPNGBDBM186936(US9079895, 24s)
Affinity DataKi:  1.65E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
University Of Dundee

US Patent
LigandPNGBDBM186933(US9079895, 23r)
Affinity DataKi:  1.85E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
University Of Dundee

US Patent
LigandPNGBDBM186932(US9079895, 22r)
Affinity DataKi:  2.36E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
University Of Dundee

US Patent
LigandPNGBDBM186941(US9079895, 27r)
Affinity DataKi:  2.56E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
University Of Dundee

US Patent
LigandPNGBDBM186938(US9079895, 25r)
Affinity DataKi:  2.69E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
University Of Dundee

US Patent
LigandPNGBDBM186939(US9079895, 26r)
Affinity DataKi:  3.17E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
University Of Dundee

US Patent
LigandPNGBDBM186968(US9079895, 70)
Affinity DataKi:  3.46E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
University Of Dundee

US Patent
LigandPNGBDBM186953(US9079895, 60)
Affinity DataKi:  4.61E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
University Of Dundee

US Patent
LigandPNGBDBM186960(US9079895, 62)
Affinity DataKi:  5.18E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
University Of Dundee

US Patent
LigandPNGBDBM186926(US9079895, 18s)
Affinity DataKi:  6.42E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
University Of Dundee

US Patent
LigandPNGBDBM186930(US9079895, 20s | US9079895, 21s)
Affinity DataKi:  7.64E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Mus musculus (Mouse))
University Of Dundee

US Patent
LigandPNGBDBM186928(US9079895, 20r)
Affinity DataKi:  8.81E+3nMpH: 7.4Assay Description:The detailed experimental protocols for the radioligand and functional receptor assays are available on the NIMH PDSP website at http://pdsp.med.un...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM249361(US9464062, 5)
Affinity DataIC50:  41nMpH: 7.4Assay Description:A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer (50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM249358(US9464062, 1)
Affinity DataIC50:  126nMpH: 7.4Assay Description:A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer (50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM249360(US9464062, 4)
Affinity DataIC50:  190nMpH: 7.4Assay Description:A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer (50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM249359(US9464062, 3)
Affinity DataIC50:  274nMpH: 7.4Assay Description:A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer (50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM249363(US9464062, 7)
Affinity DataIC50:  298nMpH: 7.4Assay Description:A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer (50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
University Of North Carolina At Chapel Hill

US Patent
LigandPNGBDBM249362(US9464062, 6)
Affinity DataIC50:  1.87E+3nMpH: 7.4Assay Description:A solution of the compound of the disclosure to be tested is prepared as a 1-mg/ml stock in Assay Buffer (50 mM Tris-HCl, 10 mM MgCl2, 1 mM EDTA, pH ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent