Found 55 of ph data with Target = 'Aldo-keto reductase family 1 member C3' 
Affinity DataKi: 6.90nM ΔG°: -48.5kJ/molepH: 7.5 T: 2°CAssay Description:A radioactive assay was used for the enzyme kinetics in the presence of EM1404 at different concentrations for its Ki determination. Reactions were i...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataKi: 140nM ΔG°: -39.8kJ/molepH: 7.0 T: 2°CAssay Description:A fluorescence assay was used to determine the kinetic constants for the oxidation of 3alpha-androstanediol. The fluorescence emission of NADPH at 45...More data for this Ligand-Target Pair
Affinity DataKi: 270nM ΔG°: -38.1kJ/molepH: 7.0 T: 2°CAssay Description:A fluorescence assay was used to determine the kinetic constants for the oxidation of 3alpha-androstanediol. The fluorescence emission of NADPH at 45...More data for this Ligand-Target Pair
Affinity DataKi: 2.10E+3nM ΔG°: -33.0kJ/molepH: 7.0 T: 2°CAssay Description:Enzyme activity was measured in the reductive direction against varying concentrations of androsterone. Initial velocities were measured by observing...More data for this Ligand-Target Pair
Affinity DataKi: 3.10E+3nM ΔG°: -32.0kJ/molepH: 7.0 T: 2°CAssay Description:Enzyme activity was measured in the reductive direction against varying concentrations of androsterone. Initial velocities were measured by observing...More data for this Ligand-Target Pair
Affinity DataKi: 9.40E+4nM ΔG°: -23.0kJ/molepH: 7.4 T: 2°CAssay Description:The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMpH: 6.0 T: 2°CAssay Description:SPA beads conjugated to anti-mouse IgG were incubated overnight in buffer with anti-testosterone monoclonal antibody. The enzymatic reaction was moni...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 5nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 6nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 8nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 9.5nMpH: 6.0 T: 2°CAssay Description:SPA beads conjugated to anti-mouse IgG were incubated overnight in buffer with anti-testosterone monoclonal antibody. The enzymatic reaction was moni...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 12nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 13nMpH: 6.0 T: 2°CAssay Description:SPA beads conjugated to anti-mouse IgG were incubated overnight in buffer with anti-testosterone monoclonal antibody. The enzymatic reaction was moni...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 19nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 27nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 29nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 45nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 46nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 48nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 54nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 60nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 61nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 73nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
Affinity DataIC50: 97nMpH: 7.0Assay Description:For the assay, 50 nl of a 100-fold concentrated solution of the test substance in DMSO were pipetted into a black low-volume 384-well microtitre plat...More data for this Ligand-Target Pair
