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Found 63 of ph data with Target = 'Cyclin-dependent kinase 1'
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM84533(Alsterpaullone derivative, 7 | BDBM50375663)
Affinity DataIC50:  0.230nMpH: 7.5 T: 2°CAssay Description:Kinase activity assay using GSK-3beta, CDK1/cyclin B and CDK5/p25.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM129353(US8802686, 11)
Affinity DataIC50:  3nMpH: 8.0 T: 2°CAssay Description:CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM6145(US8802686, 2 | US8802686, C2)
Affinity DataIC50:  4nMpH: 8.0 T: 2°CAssay Description:CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM6131(US8802686, 1 | US8802686, C1)
Affinity DataIC50:  8nMpH: 8.0 T: 2°CAssay Description:CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM6192(US8802686, 3 | US8802686, C3)
Affinity DataIC50:  9nMpH: 8.0 T: 2°CAssay Description:CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM6145(US8802686, 2 | US8802686, C2)
Affinity DataIC50:  9nMpH: 8.0 T: 2°CAssay Description:CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM59116(Hymenialdisine, 27k)
Affinity DataIC50: >10nMpH: 7.2Assay Description:In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM129351(US8802686, 9)
Affinity DataIC50:  12nMpH: 8.0 T: 2°CAssay Description:CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM6131(US8802686, 1 | US8802686, C1)
Affinity DataIC50:  16nMpH: 8.0 T: 2°CAssay Description:CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM129349(US8802686, 7)
Affinity DataIC50:  23nMpH: 8.0 T: 2°CAssay Description:CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM129348(US8802686, 6)
Affinity DataIC50:  24nMpH: 8.0 T: 2°CAssay Description:CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM84531(Alsterpaullone derivative, 5)
Affinity DataIC50:  25nMpH: 7.5 T: 2°CAssay Description:Kinase activity assay using GSK-3beta, CDK1/cyclin B and CDK5/p25.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM84530(Alsterpaullone derivative, 4)
Affinity DataIC50:  27nMpH: 7.5 T: 2°CAssay Description:Kinase activity assay using GSK-3beta, CDK1/cyclin B and CDK5/p25.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM6192(US8802686, 3 | US8802686, C3)
Affinity DataIC50:  32nMpH: 8.0 T: 2°CAssay Description:CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM7262(14-nitro-8,18-diazatetracyclo[9.7.0.0^{2,7}.0^{12,...)
Affinity DataIC50:  35nMpH: 7.5 T: 2°CAssay Description:Kinase activity assay using GSK-3beta, CDK1/cyclin B and CDK5/p25.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM129346(US8802686, 4)
Affinity DataIC50:  36nMpH: 8.0 T: 2°CAssay Description:CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM129347(US8802686, 5)
Affinity DataIC50:  41nMpH: 8.0 T: 2°CAssay Description:CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM129350(US8802686, 8)
Affinity DataIC50:  43nMpH: 8.0 T: 2°CAssay Description:CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM129354(US8802686, 12)
Affinity DataIC50:  51nMpH: 8.0 T: 2°CAssay Description:CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM7491((4Z)-4-(2-amino-5-oxo-3,5-dihydro-4H-imidazol-4-yl...)
Affinity DataIC50:  70nMpH: 7.2Assay Description:In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM84529(Alsterpaullone derivative, 3)
Affinity DataIC50:  80nMpH: 7.5 T: 2°CAssay Description:Kinase activity assay using GSK-3beta, CDK1/cyclin B and CDK5/p25.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM129352(US8802686, 10)
Affinity DataIC50:  82nMpH: 8.0 T: 2°CAssay Description:CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM164883(US9067888, 33)
Affinity DataIC50:  94nMpH: 7.5Assay Description:In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM84532(Alsterpaullone derivative, 6)
Affinity DataIC50:  100nMpH: 7.5 T: 2°CAssay Description:Kinase activity assay using GSK-3beta, CDK1/cyclin B and CDK5/p25.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM129355(US8802686, 13)
Affinity DataIC50:  130nMpH: 8.0 T: 2°CAssay Description:CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM59103(Hymenialdisine, 15)
Affinity DataIC50:  220nMpH: 7.2Assay Description:In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM16591((4Z)-4-(2-amino-5-oxo-3,5-dihydro-4H-imidazol-4-yl...)
Affinity DataIC50:  250nMpH: 7.2Assay Description:In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM129357(US8802686, 15)
Affinity DataIC50:  280nMpH: 8.0 T: 2°CAssay Description:CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM59148(Hymenialdisine, 28z)
Affinity DataIC50:  400nMpH: 7.2Assay Description:In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM59104(Hymenialdisine, 18)
Affinity DataIC50:  500nMpH: 7.2Assay Description:In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM59115(Hymenialdisine, 27j)
Affinity DataIC50:  500nMpH: 7.2Assay Description:In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM50256043((Z)-3-bromohymenialdisine | CHEMBL480350 | Hymenia...)
Affinity DataIC50:  530nMpH: 7.2Assay Description:In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM59107(Hymenialdisine, 27c)
Affinity DataIC50:  550nMpH: 7.2Assay Description:In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM129356(US8802686, 14)
Affinity DataIC50:  740nMpH: 8.0 T: 2°CAssay Description:CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM50256044(5-(2-amino-4-oxo-1H-imidazol-5(4H)-ylidene)-2,3,4,...)
Affinity DataIC50:  800nMpH: 7.2Assay Description:In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM59110(Hymenialdisine, 27e)
Affinity DataIC50:  890nMpH: 7.2Assay Description:In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM59142(Hymenialdisine, 28n)
Affinity DataIC50:  1.00E+3nMpH: 7.2Assay Description:In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM59131(Hymenialdisine, 28g)
Affinity DataIC50:  1.00E+3nMpH: 7.2Assay Description:In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM129358(US8802686, 16)
Affinity DataIC50: >1.00E+3nMpH: 8.0 T: 2°CAssay Description:CDK1/CycB (200 ng/measuring point) was incubated for 10 min at 22 C. in the presence of different concentrations of test substances (0 and within the...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM59109(Hymenialdisine, 27a)
Affinity DataIC50:  1.00E+3nMpH: 7.2Assay Description:In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM59113(Hymenialdisine, 27g)
Affinity DataIC50:  1.20E+3nMpH: 7.2Assay Description:In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM59149(Hymenialdisine, 28v)
Affinity DataIC50:  1.30E+3nMpH: 7.2Assay Description:In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM59130(Hymenialdisine, 28t)
Affinity DataIC50:  1.30E+3nMpH: 7.2Assay Description:In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM59102(Hymenialdisine, 9)
Affinity DataIC50:  1.50E+3nMpH: 7.2Assay Description:In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM59105(Hymenialdisine, 16)
Affinity DataIC50:  1.50E+3nMpH: 7.2Assay Description:In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM59114(Hymenialdisine, 27i)
Affinity DataIC50:  1.60E+3nMpH: 7.2Assay Description:In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM59112(Hymenialdisine, 27h)
Affinity DataIC50:  1.60E+3nMpH: 7.2Assay Description:In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM164884(US9067888, 34)
Affinity DataIC50:  1.88E+3nMpH: 7.5Assay Description:In vitro kinase assay analysis may be performed using standard techniques described in the art. These techniques are also used by commercial services...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM59150(Hymenialdisine, 28ae)
Affinity DataIC50:  2.00E+3nMpH: 7.2Assay Description:In vitro kinase assay using SPA assay kit from Amersham Pharmacia Biotech, Uk.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Technische UniversitÄT Braunschweig

LigandPNGBDBM50358213(CHEMBL1922219 | US8846696, (2R3S)-3-{9-Isopropyl-6...)
Affinity DataIC50:  2.20E+3nMpH: 7.4Assay Description:The compounds from the examples below were investigated for their CDK2/cyclin E, CDK1/cyclin B, CDK4/cyclin D1 and CDK7/cyclin H, ERK-2, and PKA inhi...More data for this Ligand-Target Pair
In DepthDetails US Patent
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