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Found 798 of ph data with Target = 'Heat shock protein HSP 90-alpha'
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM81731(HSP90 Inhibitor, 5)
Affinity DataKi:  60nM ΔG°:  -41.2kJ/molepH: 7.5 T: 2°CAssay Description:HSP90 inhibitors identified using Fluorescence resonance energy transfer assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM81730(HSP90 Inhibitor, 4)
Affinity DataKi:  170nM ΔG°:  -38.6kJ/molepH: 7.5 T: 2°CAssay Description:HSP90 inhibitors identified using Fluorescence resonance energy transfer assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM81729(HSP90 Inhibitor, 1 | hsp90_125)
Affinity DataKi:  320nM ΔG°:  -37.1kJ/molepH: 7.5 T: 2°CAssay Description:HSP90 inhibitors identified using Fluorescence resonance energy transfer assay.More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM81732(HSP90 Inhibitor, 6)
Affinity DataKi:  1.90E+3nM ΔG°:  -32.7kJ/molepH: 7.5 T: 2°CAssay Description:HSP90 inhibitors identified using Fluorescence resonance energy transfer assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM81733(HSP90 Inhibitor, 7)
Affinity DataKi:  4.00E+3nM ΔG°:  -30.8kJ/molepH: 7.5 T: 2°CAssay Description:HSP90 inhibitors identified using Fluorescence resonance energy transfer assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM50270588(4-METHYL-6-(TRIFLUOROMETHYL)PYRIMIDIN-2-AMINE | CH...)
Affinity DataKi:  1.80E+4nM ΔG°:  -27.1kJ/molepH: 7.5 T: 2°CAssay Description:HSP90 inhibitors identified using Fluorescence resonance energy transfer assay.More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM81917(BX-2819)
Affinity DataIC50:  0.0400nMpH: 7.4Assay Description:To assess the affinity of compounds binding to Hsp90, we measured their ability to compete with the binding of a fluorescent analog of GA (GM-Bodipy)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM81916(lspropyl analog, 5)
Affinity DataIC50:  0.100nMpH: 7.4Assay Description:To assess the affinity of compounds binding to Hsp90, we measured their ability to compete with the binding of a fluorescent analog of GA (GM-Bodipy)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM81914(Ethyl carbamate analog, 3)
Affinity DataIC50:  0.100nMpH: 7.4Assay Description:To assess the affinity of compounds binding to Hsp90, we measured their ability to compete with the binding of a fluorescent analog of GA (GM-Bodipy)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM81915(Ethyl analog, 4)
Affinity DataIC50:  0.200nMpH: 7.4Assay Description:To assess the affinity of compounds binding to Hsp90, we measured their ability to compete with the binding of a fluorescent analog of GA (GM-Bodipy)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM81912(DC23 | Resorcinol analog, 1)
Affinity DataIC50:  0.300nMpH: 7.4Assay Description:To assess the affinity of compounds binding to Hsp90, we measured their ability to compete with the binding of a fluorescent analog of GA (GM-Bodipy)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM81913(Unsubstituted phenyl ring analog, 2)
Affinity DataIC50:  0.5nMpH: 7.4Assay Description:To assess the affinity of compounds binding to Hsp90, we measured their ability to compete with the binding of a fluorescent analog of GA (GM-Bodipy)...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM110223(US8618290, 61)
Affinity DataIC50:  3nMpH: 7.3Assay Description:An in vitro competition fluorescence polarization assay in which a test compound competes with a fluorescent probe for binding to the binding domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM110229(US8618290, 85)
Affinity DataIC50:  4nMpH: 7.3Assay Description:An in vitro competition fluorescence polarization assay in which a test compound competes with a fluorescent probe for binding to the binding domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM110216(US8618290, 33)
Affinity DataIC50:  4nMpH: 7.3Assay Description:An in vitro competition fluorescence polarization assay in which a test compound competes with a fluorescent probe for binding to the binding domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM110226(US8618290, 78)
Affinity DataIC50:  4nMpH: 7.3Assay Description:An in vitro competition fluorescence polarization assay in which a test compound competes with a fluorescent probe for binding to the binding domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM110221(US8618290, 58)
Affinity DataIC50:  5nMpH: 7.3Assay Description:An in vitro competition fluorescence polarization assay in which a test compound competes with a fluorescent probe for binding to the binding domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM110227(US8618290, 79)
Affinity DataIC50:  6nMpH: 7.3Assay Description:An in vitro competition fluorescence polarization assay in which a test compound competes with a fluorescent probe for binding to the binding domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM110218(US8618290, 37)
Affinity DataIC50:  6nMpH: 7.3Assay Description:An in vitro competition fluorescence polarization assay in which a test compound competes with a fluorescent probe for binding to the binding domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM110222(US8618290, 59)
Affinity DataIC50:  8nMpH: 7.3Assay Description:An in vitro competition fluorescence polarization assay in which a test compound competes with a fluorescent probe for binding to the binding domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM110228(US8618290, 83)
Affinity DataIC50:  8nMpH: 7.3Assay Description:An in vitro competition fluorescence polarization assay in which a test compound competes with a fluorescent probe for binding to the binding domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM110230(US8618290, 93)
Affinity DataIC50:  8nMpH: 7.3Assay Description:An in vitro competition fluorescence polarization assay in which a test compound competes with a fluorescent probe for binding to the binding domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM110232(US8618290, 99)
Affinity DataIC50:  8nMpH: 7.3Assay Description:An in vitro competition fluorescence polarization assay in which a test compound competes with a fluorescent probe for binding to the binding domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM110224(US8618290, 65)
Affinity DataIC50:  10nMpH: 7.3Assay Description:An in vitro competition fluorescence polarization assay in which a test compound competes with a fluorescent probe for binding to the binding domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM110225(US8618290, 75)
Affinity DataIC50:  10nMpH: 7.3Assay Description:An in vitro competition fluorescence polarization assay in which a test compound competes with a fluorescent probe for binding to the binding domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM110220(US8618290, 45)
Affinity DataIC50:  10nMpH: 7.3Assay Description:An in vitro competition fluorescence polarization assay in which a test compound competes with a fluorescent probe for binding to the binding domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM110219(US8618290, 40)
Affinity DataIC50:  10nMpH: 7.3Assay Description:An in vitro competition fluorescence polarization assay in which a test compound competes with a fluorescent probe for binding to the binding domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM110231(US8618290, 96)
Affinity DataIC50:  13nMpH: 7.3Assay Description:An in vitro competition fluorescence polarization assay in which a test compound competes with a fluorescent probe for binding to the binding domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM110217(US8618290, 35)
Affinity DataIC50:  13nMpH: 7.3Assay Description:An in vitro competition fluorescence polarization assay in which a test compound competes with a fluorescent probe for binding to the binding domain ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM279646(3-(2,4-dihydroxyl-5-isopropylphenyl)-4-(2-methyl-1...)
Affinity DataIC50: <20nMpH: 7.4Assay Description:The fluorescent labeled small molecule used in the present invention was VER-00051001 (synthesized by reference to the synthetic method described in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM279647(3-(2,4-dihydroxyl-5-isopropylphenyl)-N-methyl-4-(2...)
Affinity DataIC50: <20nMpH: 7.4Assay Description:The fluorescent labeled small molecule used in the present invention was VER-00051001 (synthesized by reference to the synthetic method described in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM279648(3-(2,4-dihydroxyl-5-isopropylphenyl)-N-isopropyl-4...)
Affinity DataIC50: <20nMpH: 7.4Assay Description:The fluorescent labeled small molecule used in the present invention was VER-00051001 (synthesized by reference to the synthetic method described in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM279649(3-(2,4-dihydroxyl-5-isopropylphenyl)-N-(2-hydroxyl...)
Affinity DataIC50: <20nMpH: 7.4Assay Description:The fluorescent labeled small molecule used in the present invention was VER-00051001 (synthesized by reference to the synthetic method described in ...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM279650(3-(2,4-dihydroxyl-5-isopropylphenyl)-N-(2-fluoroet...)
Affinity DataIC50: <20nMpH: 7.4Assay Description:The fluorescent labeled small molecule used in the present invention was VER-00051001 (synthesized by reference to the synthetic method described in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM279651(3-(2,4-dihydroxyl-5-isopropylphenyl)-N-(3-hydroxyl...)
Affinity DataIC50: <20nMpH: 7.4Assay Description:The fluorescent labeled small molecule used in the present invention was VER-00051001 (synthesized by reference to the synthetic method described in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM279652(3-(2,4-dihydroxyl-5-isopropylphenyl)-N-ethyl-4-(1,...)
Affinity DataIC50: <20nMpH: 7.4Assay Description:The fluorescent labeled small molecule used in the present invention was VER-00051001 (synthesized by reference to the synthetic method described in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM279586(5-(2,4-dihydroxyl-5-isopropylphenyl)-N-ethyl-4-(2-...)
Affinity DataIC50: <20nMpH: 7.4Assay Description:The fluorescent labeled small molecule used in the present invention was VER-00051001 (synthesized by reference to the synthetic method described in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM20732((4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,...)
Affinity DataIC50:  20nMpH: 7.3 T: 2°CAssay Description:Compounds were assayed over a threefold dilution series in a 96-well plate format to determine IC50 values. The reaction was allowed to proceed with ...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM279634(5-(2,4-dihydroxyl-5-isopropylphenyl)-N-ethyl-4-(2-...)
Affinity DataIC50: <20nMpH: 7.4Assay Description:The fluorescent labeled small molecule used in the present invention was VER-00051001 (synthesized by reference to the synthetic method described in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM279630(5-(2,4-dihydroxyl-5-isopropylphenyl)-N-ethyl-4-(2-...)
Affinity DataIC50: <20nMpH: 7.4Assay Description:The fluorescent labeled small molecule used in the present invention was VER-00051001 (synthesized by reference to the synthetic method described in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM279629(5-(2,4-dihydroxyl-5-isopropylphenyl)-N-ethyl-4-(2-...)
Affinity DataIC50: <20nMpH: 7.4Assay Description:The fluorescent labeled small molecule used in the present invention was VER-00051001 (synthesized by reference to the synthetic method described in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM279626(5-(2,4-dihydroxyl-5-isopropylphenyl)-N-(2-methoxye...)
Affinity DataIC50: <20nMpH: 7.4Assay Description:The fluorescent labeled small molecule used in the present invention was VER-00051001 (synthesized by reference to the synthetic method described in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM279625(5-(2,4-dihydroxyl-5-isopropylphenyl)-N-(2-fluoroet...)
Affinity DataIC50: <20nMpH: 7.4Assay Description:The fluorescent labeled small molecule used in the present invention was VER-00051001 (synthesized by reference to the synthetic method described in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM279621(5-(2,4-dihydroxyl-5-isopropylphenyl)-N-methyl-4-(2...)
Affinity DataIC50: <20nMpH: 7.4Assay Description:The fluorescent labeled small molecule used in the present invention was VER-00051001 (synthesized by reference to the synthetic method described in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM279620(5-(5-cyclopropyl-2,4-dihydroxyl-phenyl)-N-ethyl-4-...)
Affinity DataIC50: <20nMpH: 7.4Assay Description:The fluorescent labeled small molecule used in the present invention was VER-00051001 (synthesized by reference to the synthetic method described in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM279619(5-(5-ethyl-2,4-dihydroxyl-phenyl)-N-ethyl-4-(2-met...)
Affinity DataIC50: <20nMpH: 7.4Assay Description:The fluorescent labeled small molecule used in the present invention was VER-00051001 (synthesized by reference to the synthetic method described in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM279617(5-(2,4-dihydroxyl-5-methylphenyl)-N-ethyl-4-(2-met...)
Affinity DataIC50: <20nMpH: 7.4Assay Description:The fluorescent labeled small molecule used in the present invention was VER-00051001 (synthesized by reference to the synthetic method described in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM279614(3-(2,4-dihydroxyl-5-isopropylphenyl)-N-ethyl-4-(is...)
Affinity DataIC50: <20nMpH: 7.4Assay Description:The fluorescent labeled small molecule used in the present invention was VER-00051001 (synthesized by reference to the synthetic method described in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM279613(3-(2,4-dihydroxyl-5-isopropylphenyl)-N-ethyl-4-(2,...)
Affinity DataIC50: <20nMpH: 7.4Assay Description:The fluorescent labeled small molecule used in the present invention was VER-00051001 (synthesized by reference to the synthetic method described in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHeat shock protein HSP 90-alpha(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM279612(3-(2,4-dihydroxyl-5-isopropylphenyl)-N-ethyl-4-(3-...)
Affinity DataIC50: <20nMpH: 7.4Assay Description:The fluorescent labeled small molecule used in the present invention was VER-00051001 (synthesized by reference to the synthetic method described in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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