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Found 9 of ph data with Target = 'Kappa-type opioid receptor [Y320F]'
TargetKappa-type opioid receptor [Y320F](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214798(Dynorphin A (1-17) | YGGFLRRIRPKLK)
Affinity DataKi:  18nM ΔG°:  -44.2kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [Y320F](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM50159165((2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(fura...)
Affinity DataKi:  80nM ΔG°:  -40.5kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [Y320F](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM21130(N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl...)
Affinity DataKi:  190nM ΔG°:  -38.4kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [Y320F](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataKi:  470nM ΔG°:  -36.1kJ/molepH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [Y320F](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214799(1xx)
Affinity DataEC50:  300nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [Y320F](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM50159165((2S,4aR,6aR,7R,9S,10aS,10bR)-9-(acetyloxy)-2-(fura...)
Affinity DataEC50:  21nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [Y320F](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM21130(N-methyl-2-phenyl-N-[(5R,7S,8S)-7-(pyrrolidin-1-yl...)
Affinity DataEC50:  150nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [Y320F](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM214798(Dynorphin A (1-17) | YGGFLRRIRPKLK)
Affinity DataEC50:  76nMpH: 7.4Assay Description:HEK293T cells were co-transfected with plasmids encoding the cAMP biosensor GloSensor-22F (Promega) and the different human KOR variants as described...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor [Y320F](Homo sapiens (Human))
University Of North Carolina

LigandPNGBDBM50001714(2-[3-cyclopropylmethyl-11-hydroxy-15-methoxy-(1S,2...)
Affinity DataKd:  1.40nMpH: 7.4 T: 2°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed