Compile Data Set for Download or QSAR
maximum 50k data
Found 79 of ph data with Target = 'Phenylalanine--tRNA ligase alpha/beta subunit'
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (Enterobacteria))
Astrazeneca R&D Boston

LigandPNGBDBM231666(N-(2-(1H-indol-3-yl)ethyl)-3-(3-thiazol-2-ylureido...)
Affinity DataIC50:  2.20nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (Enterobacteria))
Astrazeneca R&D Boston

LigandPNGBDBM231665(1-(3-(4-(Pyridin-2-yl)piperazin-1-ylsulfonyl)pheny...)
Affinity DataIC50:  2.70nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18116(2-[2-({[(2R)-2-(4-bromothiophen-2-yl)-2-hydroxyeth...)
Affinity DataIC50:  3.70nMpH: 2.0Assay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18093(2-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl]am...)
Affinity DataIC50:  8nMpH: 7.9 T: 2°CAssay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18098(2-({[2-(benzyloxy)phenyl]methyl}amino)-1-(4-bromot...)
Affinity DataIC50:  10nMpH: 7.9 T: 2°CAssay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Pseudomonas aeruginosa)
Astrazeneca R&D Boston

LigandPNGBDBM231666(N-(2-(1H-indol-3-yl)ethyl)-3-(3-thiazol-2-ylureido...)
Affinity DataIC50:  13nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18102(1-(4-bromothiophen-2-yl)-2-({[2-(pyridin-4-ylmetho...)
Affinity DataIC50:  16nMpH: 2.0Assay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18101(1-(4-bromothiophen-2-yl)-2-({[2-(pyridin-3-ylmetho...)
Affinity DataIC50:  18nMpH: 2.0Assay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18096(1-(4-bromothiophen-2-yl)-2-[({2-[2-(morpholin-4-yl...)
Affinity DataIC50:  18nMpH: 7.9 T: 2°CAssay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18097(1-(4-bromothiophen-2-yl)-2-({[2-(prop-2-en-1-yloxy...)
Affinity DataIC50:  18nMpH: 7.9 T: 2°CAssay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18114(2-({[2-(4-aminobutoxy)phenyl]methyl}amino)-1-(4-br...)
Affinity DataIC50:  22nMpH: 2.0Assay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Pseudomonas aeruginosa)
Astrazeneca R&D Boston

LigandPNGBDBM231665(1-(3-(4-(Pyridin-2-yl)piperazin-1-ylsulfonyl)pheny...)
Affinity DataIC50:  22nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18110(3-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl]am...)
Affinity DataIC50:  25nMpH: 2.0Assay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18103(2-({[2-(1H-1,3-benzodiazol-2-ylmethoxy)phenyl]meth...)
Affinity DataIC50:  26nMpH: 2.0Assay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18113(4-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl]am...)
Affinity DataIC50:  26nMpH: 2.0Assay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18099(1-(4-bromothiophen-2-yl)-2-[({2-[(4-methanesulfony...)
Affinity DataIC50:  26nMpH: 7.9 T: 2°CAssay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18112(4-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl]am...)
Affinity DataIC50:  30nMpH: 2.0Assay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18085(2-({[2-(benzyloxy)phenyl]methyl}amino)-1-(3-chloro...)
Affinity DataIC50:  31nMpH: 7.9 T: 2°CAssay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18086(2-({[2-(benzyloxy)phenyl]methyl}amino)-1-(3-iodoph...)
Affinity DataIC50:  32nMpH: 7.9 T: 2°CAssay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18105(2-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl]am...)
Affinity DataIC50:  32nMpH: 2.0Assay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18091(1-(4-bromothiophen-2-yl)-2-({[2-(methoxymethoxy)ph...)
Affinity DataIC50:  35nMpH: 7.9 T: 2°CAssay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18109(3-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl]am...)
Affinity DataIC50:  36nMpH: 2.0Assay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18104(2-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl]am...)
Affinity DataIC50:  42nMpH: 2.0Assay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18100(1-(4-bromothiophen-2-yl)-2-({[2-(pyridin-2-ylmetho...)
Affinity DataIC50:  43nMpH: 7.9 T: 2°CAssay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18111(4-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl]am...)
Affinity DataIC50:  43nMpH: 2.0Assay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18092(2-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl]am...)
Affinity DataIC50:  49nMpH: 7.9 T: 2°CAssay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18089(1-(4-bromothiophen-2-yl)-2-{[(2-methoxyphenyl)meth...)
Affinity DataIC50:  50nMpH: 7.9 T: 2°CAssay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18081(2-({[2-(benzyloxy)phenyl]methyl}amino)-1-[3-(trifl...)
Affinity DataIC50:  50nMpH: 7.9 T: 2°CAssay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Haemophilus influenzae)
Gsk

LigandPNGBDBM18116(2-[2-({[(2R)-2-(4-bromothiophen-2-yl)-2-hydroxyeth...)
Affinity DataIC50:  56nMpH: 2.0Assay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18080(2-({[2-(prop-2-en-1-yloxy)phenyl]methyl}amino)-1-[...)
Affinity DataIC50:  58nMpH: 7.9 T: 2°CAssay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18108(3-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl]am...)
Affinity DataIC50:  58nMpH: 2.0Assay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (Enterobacteria))
Astrazeneca R&D Boston

LigandPNGBDBM231670(5-(3-Methoxyphenyl)-3-(trifluoromethyl)-1H-pyrazol...)
Affinity DataIC50:  60nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18115(2-{4-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl...)
Affinity DataIC50:  69nMpH: 2.0Assay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (Enterobacteria))
Astrazeneca R&D Boston

LigandPNGBDBM231674(N-(2-(1-(methylsulfonyl)cyclopropyl)ethyl)-2-(3-(5...)
Affinity DataIC50:  70nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (Enterobacteria))
Astrazeneca R&D Boston

LigandPNGBDBM231671(Ethyl 2-(3-(5-(trifluoromethyl)-1H-pyrazol-3-yl)ph...)
Affinity DataIC50:  80nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18087(2-({[2-(benzyloxy)phenyl]methyl}amino)-1-(3-methox...)
Affinity DataIC50:  83nMpH: 7.9 T: 2°CAssay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (Enterobacteria))
Astrazeneca R&D Boston

LigandPNGBDBM231669(2-[3-[(4-Chloro-2-pyridyl)amino]phenoxy]-N-(1,1-di...)
Affinity DataIC50:  100nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18077(2-[({2-hydroxy-2-[3-(trifluoromethyl)phenyl]ethyl}...)
Affinity DataIC50:  100nMpH: 7.9 T: 2°CAssay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (Enterobacteria))
Astrazeneca R&D Boston

LigandPNGBDBM231676(2-((4-Chlorophenoxy)methyl)-N-(cyanomethyl)thiazol...)
Affinity DataIC50:  100nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18082(1-(3-bromophenyl)-2-{[(2-methoxyphenyl)methyl]amin...)
Affinity DataIC50:  110nMpH: 7.9 T: 2°CAssay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18083(2-{[(2-methoxyphenyl)methyl]amino}-1-(3-methylphen...)
Affinity DataIC50:  110nMpH: 7.9 T: 2°CAssay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18107(2-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl]am...)
Affinity DataIC50:  110nMpH: 2.0Assay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18106(2-[2-({[2-(4-bromothiophen-2-yl)-2-hydroxyethyl]am...)
Affinity DataIC50:  120nMpH: 2.0Assay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18090(1-(4-bromothiophen-2-yl)-2-{[(2-phenoxyphenyl)meth...)
Affinity DataIC50:  120nMpH: 7.9 T: 2°CAssay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Haemophilus influenzae)
Gsk

LigandPNGBDBM18103(2-({[2-(1H-1,3-benzodiazol-2-ylmethoxy)phenyl]meth...)
Affinity DataIC50:  150nMpH: 2.0Assay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18072(2-(benzylamino)-1-[3-(trifluoromethyl)phenyl]ethan...)
Affinity DataIC50:  160nMpH: 7.9 T: 2°CAssay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18079(2-{[(2-methoxyphenyl)methyl]amino}-1-[3-(trifluoro...)
Affinity DataIC50:  160nMpH: 7.9 T: 2°CAssay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Streptococcus pneumoniae)
Gsk

LigandPNGBDBM18116(2-[2-({[(2R)-2-(4-bromothiophen-2-yl)-2-hydroxyeth...)
Affinity DataIC50:  190nMpH: 2.0Assay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Escherichia coli (Enterobacteria))
Astrazeneca R&D Boston

LigandPNGBDBM231677(2-((4-Chlorophenoxy)methyl)-N-(2-sulfamoylethyl)th...)
Affinity DataIC50:  190nMpH: 8.0Assay Description:Compounds were solubilized in DMSO. Serial 2-fold dilutions covering two concentration ranges, 10 mM to 19.5 μM and 100 μM to 195 nM, were ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPhenylalanine--tRNA ligase alpha/beta subunit(Staphylococcus aureus)
Gsk

LigandPNGBDBM18084(2-{[(2-methoxyphenyl)methyl]amino}-1-[3-(trifluoro...)
Affinity DataIC50:  190nMpH: 7.9 T: 2°CAssay Description:The reactions were performed in 96-well Packard 384-well Packard Optiplates. After 10 min of incubation, the reaction was stopped by addition of a co...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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