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Found 8 of ph data with Target = 'Ribonuclease H1'
TargetRibonuclease H1(Homo sapiens (Human))
National Cancer Institute-Bethesda

LigandPNGBDBM33045(2-amino-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophe...)
Affinity DataIC50:  1.06E+4nMpH: 8.0 T: 2°CAssay Description:RNaseH assays were performed using an 18-nucleotide 3-fluorescein-labeled RNA annealed to a complementary 18-nucleotide 5-dabcyl conjugated DNA. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease H1(Homo sapiens (Human))
National Cancer Institute-Bethesda

LigandPNGBDBM33963(vinylogous urea, NSC727448)
Affinity DataIC50:  2.90E+4nMpH: 8.0 T: 2°CAssay Description:RNaseH assays were performed using an 18-nucleotide 3-fluorescein-labeled RNA annealed to a complementary 18-nucleotide 5-dabcyl conjugated DNA. The ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease H1(Homo sapiens (Human))
National Cancer Institute-Bethesda

LigandPNGBDBM33419(pyrimidinol carboxylic acid, 11)
Affinity DataIC50:  4.85E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetRibonuclease H1(Homo sapiens (Human))
National Cancer Institute-Bethesda

LigandPNGBDBM33418(pyrimidinol carboxylic acid, 10)
Affinity DataIC50:  7.40E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease H1(Homo sapiens (Human))
National Cancer Institute-Bethesda

LigandPNGBDBM33416(pyrimidinol carboxylic acid, 8)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease H1(Homo sapiens (Human))
National Cancer Institute-Bethesda

LigandPNGBDBM33415(CHEMBL204900 | pyrimidinol carboxylic acid, 7)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease H1(Homo sapiens (Human))
National Cancer Institute-Bethesda

LigandPNGBDBM33414(CHEMBL440562 | pyrimidinol carboxylic acid, 6)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRibonuclease H1(Homo sapiens (Human))
National Cancer Institute-Bethesda

LigandPNGBDBM33417(pyrimidinol carboxylic acid, 9)
Affinity DataIC50: >1.00E+5nMpH: 8.0 T: 2°CAssay Description:Enzyme activity was measuring substrate hydrolysis of RNase H. The intact substrate has a low background fluorescent signal and provides up to 50-fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed