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Found 16 of ph data with Target = 'S-methyl-5'-thioinosine phosphorylase'
TargetS-methyl-5'-thioinosine phosphorylase(Pseudomonas aeruginosa)
Albert Einstein College Of Medicine

US Patent
LigandPNGBDBM50247150(5'-phenylthio-ImmH | CHEMBL474328 | US9290501, (B))
Affinity DataKi:  0.0350nM ΔG°:  -59.7kJ/molepH: 7.4 T: 2°CAssay Description:Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetS-methyl-5'-thioinosine phosphorylase(Pseudomonas aeruginosa)
Albert Einstein College Of Medicine

US Patent
LigandPNGBDBM218675(US9290501, PT-ImmH)
Affinity DataKi:  0.0350nM ΔG°:  -59.7kJ/molepH: 7.4 T: 2°CAssay Description:Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetS-methyl-5'-thioinosine phosphorylase(Pseudomonas aeruginosa)
Albert Einstein College Of Medicine

US Patent
LigandPNGBDBM218673(US9290501, PrT-DADMe-ImmH)
Affinity DataKi:  0.0720nM ΔG°:  -57.9kJ/molepH: 7.4 T: 2°CAssay Description:Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetS-methyl-5'-thioinosine phosphorylase(Pseudomonas aeruginosa)
Albert Einstein College Of Medicine

US Patent
LigandPNGBDBM50247149(5'-Methylthio-ImmH | CHEMBL473929 | US9290501, (A))
Affinity DataKi:  0.0760nM ΔG°:  -57.8kJ/molepH: 7.4 T: 2°CAssay Description:Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetS-methyl-5'-thioinosine phosphorylase(Pseudomonas aeruginosa)
Albert Einstein College Of Medicine

US Patent
LigandPNGBDBM218674(US9290501, MT-ImmH)
Affinity DataKi:  0.0760nM ΔG°:  -57.8kJ/molepH: 7.4 T: 2°CAssay Description:Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetS-methyl-5'-thioinosine phosphorylase(Pseudomonas aeruginosa)
Albert Einstein College Of Medicine

US Patent
LigandPNGBDBM50246594((+/-)-7-((1-hydroxy-3-(methylthio)propan-2-ylamino...)
Affinity DataKi:  0.0960nM ΔG°:  -57.2kJ/molepH: 7.4 T: 2°CAssay Description:Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetS-methyl-5'-thioinosine phosphorylase(Pseudomonas aeruginosa)
Albert Einstein College Of Medicine

US Patent
LigandPNGBDBM50246594((+/-)-7-((1-hydroxy-3-(methylthio)propan-2-ylamino...)
Affinity DataKi:  0.0960nM ΔG°:  -57.2kJ/molepH: 7.4 T: 2°CAssay Description:Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetS-methyl-5'-thioinosine phosphorylase(Pseudomonas aeruginosa)
Albert Einstein College Of Medicine

US Patent
LigandPNGBDBM50247151(7-(((3R,4S)-3-hydroxy-4-(methylthiomethyl)pyrrolid...)
Affinity DataKi:  0.340nM ΔG°:  -54.0kJ/molepH: 7.4 T: 2°CAssay Description:Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetS-methyl-5'-thioinosine phosphorylase(Pseudomonas aeruginosa)
Albert Einstein College Of Medicine

US Patent
LigandPNGBDBM218676(US9290501, MT-DADMe-ImmH)
Affinity DataKi:  0.340nM ΔG°:  -54.0kJ/molepH: 7.4 T: 2°CAssay Description:Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetS-methyl-5'-thioinosine phosphorylase(Pseudomonas aeruginosa)
Albert Einstein College Of Medicine

US Patent
LigandPNGBDBM218673(US9290501, PrT-DADMe-ImmH)
Affinity DataKi:  0.380nM ΔG°:  -53.8kJ/molepH: 7.4 T: 2°CAssay Description:Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetS-methyl-5'-thioinosine phosphorylase(Pseudomonas aeruginosa)
Albert Einstein College Of Medicine

US Patent
LigandPNGBDBM218675(US9290501, PT-ImmH)
Affinity DataKi:  0.660nM ΔG°:  -52.4kJ/molepH: 7.4 T: 2°CAssay Description:Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetS-methyl-5'-thioinosine phosphorylase(Pseudomonas aeruginosa)
Albert Einstein College Of Medicine

US Patent
LigandPNGBDBM50246594((+/-)-7-((1-hydroxy-3-(methylthio)propan-2-ylamino...)
Affinity DataKi:  0.720nM ΔG°:  -52.2kJ/molepH: 7.4 T: 2°CAssay Description:Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetS-methyl-5'-thioinosine phosphorylase(Pseudomonas aeruginosa)
Albert Einstein College Of Medicine

US Patent
LigandPNGBDBM218676(US9290501, MT-DADMe-ImmH)
Affinity DataKi:  0.800nM ΔG°:  -51.9kJ/molepH: 7.4 T: 2°CAssay Description:Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetS-methyl-5'-thioinosine phosphorylase(Pseudomonas aeruginosa)
Albert Einstein College Of Medicine

US Patent
LigandPNGBDBM218674(US9290501, MT-ImmH)
Affinity DataKi:  0.840nM ΔG°:  -51.8kJ/molepH: 7.4 T: 2°CAssay Description:Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetS-methyl-5'-thioinosine phosphorylase(Pseudomonas aeruginosa)
Albert Einstein College Of Medicine

US Patent
LigandPNGBDBM218677(US9290501, 4'-HO-MT-DADMe-ImmH)
Affinity DataKi:  1.21nM ΔG°:  -50.9kJ/molepH: 7.4 T: 2°CAssay Description:Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetS-methyl-5'-thioinosine phosphorylase(Pseudomonas aeruginosa)
Albert Einstein College Of Medicine

US Patent
LigandPNGBDBM136302(US8853224, 12 | US9290501, MT-TrisMe-ImmH)
Affinity DataKi:  19nM ΔG°:  -44.1kJ/molepH: 7.4 T: 2°CAssay Description:Assays for slow-onset inhibitors were carried out by adding 1 nM PaMTIP into reaction mixtures at 25 °C. containing 100 mM Hepes, pH 7.4, 100 mM ...More data for this Ligand-Target Pair
In DepthDetails US Patent