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Found 174 of ph data with Target = 'Substance-P receptor'
TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM21007(C-terminal modified bifunctional peptide, 1 | H-Ty...)
Affinity DataKi:  0.0460nM ΔG°:  -59.0kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Rattus norvegicus (rat))
University Of Arizona Tucson

LigandPNGBDBM21022(Bifunctional Peptide Ligand, 6 (TY023) | H-Tyr-D-A...)
Affinity DataKi:  0.200nM ΔG°:  -55.4kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Rattus norvegicus (rat))
University Of Arizona Tucson

LigandPNGBDBM21021(Bifunctional Peptide Ligand, 5 (TY005) | CHEMBL389...)
Affinity DataKi:  0.290nM ΔG°:  -54.4kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Rattus norvegicus (rat))
University Of Arizona Tucson

LigandPNGBDBM21023(Bifunctional Peptide Ligand, 7 (TY018) | H-Tyr-D-A...)
Affinity DataKi:  0.600nM ΔG°:  -52.6kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM21012((2S)-2-{[(2S)-1-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3...)
Affinity DataKi:  0.610nM ΔG°:  -52.6kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Rattus norvegicus (rat))
University Of Arizona Tucson

LigandPNGBDBM21024(Bifunctional Peptide Ligand, 8 (TY019) | H-Tyr-D-A...)
Affinity DataKi:  0.710nM ΔG°:  -52.2kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM21016(CHEMBL22870 | L 732138 | L-732,138 | L732138 | N-a...)
Affinity DataKi:  0.730nM ΔG°:  -52.1kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Rattus norvegicus (rat))
University Of Arizona Tucson

LigandPNGBDBM21020(Bifunctional Peptide Ligand, 4 (TY004) | H-Tyr-D-A...)
Affinity DataKi:  0.800nM ΔG°:  -51.9kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Rattus norvegicus (rat))
University Of Arizona Tucson

LigandPNGBDBM21017(Bifunctional Peptide Ligand, 1 (TY003) | H-Tyr-D-A...)
Affinity DataKi:  0.880nM ΔG°:  -51.7kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Rattus norvegicus (rat))
University Of Arizona Tucson

LigandPNGBDBM21019(Bifunctional Peptide Ligand, 3 (TY006) | H-Tyr-D-A...)
Affinity DataKi:  1nM ΔG°:  -51.4kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM21013((2S)-2-{[(2S)-1-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3...)
Affinity DataKi:  1.40nM ΔG°:  -50.5kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Rattus norvegicus (rat))
University Of Arizona Tucson

LigandPNGBDBM21007(C-terminal modified bifunctional peptide, 1 | H-Ty...)
Affinity DataKi:  1.60nM ΔG°:  -50.2kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM21011((2S)-2-{[(2S)-1-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3...)
Affinity DataKi:  1.60nM ΔG°:  -50.2kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Rattus norvegicus (rat))
University Of Arizona Tucson

LigandPNGBDBM21018(Bifunctional Peptide Ligand, 2 (TY007) | H-Tyr-D-A...)
Affinity DataKi:  3nM ΔG°:  -48.6kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Rattus norvegicus (rat))
University Of Arizona Tucson

LigandPNGBDBM21013((2S)-2-{[(2S)-1-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3...)
Affinity DataKi:  6.10nM ΔG°:  -46.9kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM21010((2S)-2-{[(2S)-1-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3...)
Affinity DataKi:  14nM ΔG°:  -44.8kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Rattus norvegicus (rat))
University Of Arizona Tucson

LigandPNGBDBM21012((2S)-2-{[(2S)-1-[(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3...)
Affinity DataKi:  33nM ΔG°:  -42.7kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM21009(C-terminal modified bifunctional peptide, 2 | H-Ty...)
Affinity DataKi:  100nM ΔG°:  -40.0kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Rattus norvegicus (rat))
University Of Arizona Tucson

LigandPNGBDBM21016(CHEMBL22870 | L 732138 | L-732,138 | L732138 | N-a...)
Affinity DataKi:  130nM ΔG°:  -39.3kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Rattus norvegicus (rat))
University Of Arizona Tucson

LigandPNGBDBM21016(CHEMBL22870 | L 732138 | L-732,138 | L732138 | N-a...)
Affinity DataKi:  134nM ΔG°:  -39.2kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Rattus norvegicus (rat))
University Of Arizona Tucson

LigandPNGBDBM21009(C-terminal modified bifunctional peptide, 2 | H-Ty...)
Affinity DataKi:  270nM ΔG°:  -37.5kJ/molepH: 7.4 T: 2°CAssay Description:Log IC50 values for each test compound were determined from nonlinear regression analysis of data collected from two independent experiments performe...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM251918(US10065961, Compound 17 | US10683295, Compound 17 ...)
Affinity DataKi:  6.06E+3nM ΔG°:  -29.8kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK1 receptor was evaluated in CHO recombinant cells which express the human NK1 receptor. Membrane...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM251918(US10065961, Compound 17 | US10683295, Compound 17 ...)
Affinity DataKi:  6.06E+3nM ΔG°:  -29.8kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK1 receptor was evaluated in CHO recombinant cells which express the human NK1 receptor. Membrane...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.5kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK1 receptor was evaluated in CHO recombinant cells which express the human NK1 receptor. Membrane...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM251913(US10065961, Compound 11 | US10683295, Compound 11 ...)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.5kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK1 receptor was evaluated in CHO recombinant cells which express the human NK1 receptor. Membrane...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM50081363(CHEMBL3422012 | US10065961, Compound 3 | US1068329...)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.5kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK1 receptor was evaluated in CHO recombinant cells which express the human NK1 receptor. Membrane...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM50081197(CHEMBL3422017 | US10065961, Compound 23 | US106832...)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.5kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK1 receptor was evaluated in CHO recombinant cells which express the human NK1 receptor. Membrane...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM251928(US10065961, Compound 31 | US10683295, Compound 31 ...)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.5kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK1 receptor was evaluated in CHO recombinant cells which express the human NK1 receptor. Membrane...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM251913(US10065961, Compound 11 | US10683295, Compound 11 ...)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.5kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK1 receptor was evaluated in CHO recombinant cells which express the human NK1 receptor. Membrane...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM50081363(CHEMBL3422012 | US10065961, Compound 3 | US1068329...)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.5kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK1 receptor was evaluated in CHO recombinant cells which express the human NK1 receptor. Membrane...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM251928(US10065961, Compound 31 | US10683295, Compound 31 ...)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.5kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK1 receptor was evaluated in CHO recombinant cells which express the human NK1 receptor. Membrane...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM242740(US10030025, Compound 1 | US10836768, Cpd no 1 | US...)
Affinity DataKi:  1.03E+4nM ΔG°:  -28.5kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK-1 receptor was evaluated in CHO recombinant cells which express the human NK-1 receptor. Membra...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM242740(US10030025, Compound 1 | US10836768, Cpd no 1 | US...)
Affinity DataKi:  1.03E+4nM ΔG°:  -28.5kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK-1 receptor was evaluated in CHO recombinant cells which express the human NK-1 receptor. Membra...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM50081195(CHEMBL3422010 | US10065961, Compound 1 | US1068329...)
Affinity DataKi:  1.27E+4nM ΔG°:  -27.9kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK1 receptor was evaluated in CHO recombinant cells which express the human NK1 receptor. Membrane...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM50081195(CHEMBL3422010 | US10065961, Compound 1 | US1068329...)
Affinity DataKi:  1.27E+4nM ΔG°:  -27.9kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK1 receptor was evaluated in CHO recombinant cells which express the human NK1 receptor. Membrane...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM50081293(CHEMBL3422007 | US10065961, Compound 30 | US106832...)
Affinity DataKi:  1.72E+4nM ΔG°:  -27.2kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK1 receptor was evaluated in CHO recombinant cells which express the human NK1 receptor. Membrane...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM50081293(CHEMBL3422007 | US10065961, Compound 30 | US106832...)
Affinity DataKi:  1.72E+4nM ΔG°:  -27.2kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK1 receptor was evaluated in CHO recombinant cells which express the human NK1 receptor. Membrane...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM242742(US10030025, Compound 4 | US10836768, Cpd no 4 | US...)
Affinity DataKi:  1.99E+4nM ΔG°:  -26.8kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK-1 receptor was evaluated in CHO recombinant cells which express the human NK-1 receptor. Membra...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM242742(US10030025, Compound 4 | US10836768, Cpd no 4 | US...)
Affinity DataKi:  1.99E+4nM ΔG°:  -26.8kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK-1 receptor was evaluated in CHO recombinant cells which express the human NK-1 receptor. Membra...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM242772(US10030025, Compound 38 | US10836768, Cpd no 38 | ...)
Affinity DataKi:  2.10E+4nM ΔG°:  -26.7kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK-1 receptor was evaluated in CHO recombinant cells which express the human NK-1 receptor. Membra...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM242772(US10030025, Compound 38 | US10836768, Cpd no 38 | ...)
Affinity DataKi:  2.10E+4nM ΔG°:  -26.7kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK-1 receptor was evaluated in CHO recombinant cells which express the human NK-1 receptor. Membra...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM50112245(CHEMBL3608741 | US10030025, Compound 11 | US108367...)
Affinity DataKi:  2.20E+4nM ΔG°:  -26.6kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK-1 receptor was evaluated in CHO recombinant cells which express the human NK-1 receptor. Membra...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM50112245(CHEMBL3608741 | US10030025, Compound 11 | US108367...)
Affinity DataKi:  2.20E+4nM ΔG°:  -26.6kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK-1 receptor was evaluated in CHO recombinant cells which express the human NK-1 receptor. Membra...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM242743(US10030025, Compound 6 | US10836768, Cpd no 6 | US...)
Affinity DataKi:  2.21E+4nM ΔG°:  -26.6kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK-1 receptor was evaluated in CHO recombinant cells which express the human NK-1 receptor. Membra...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM242743(US10030025, Compound 6 | US10836768, Cpd no 6 | US...)
Affinity DataKi:  2.21E+4nM ΔG°:  -26.6kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK-1 receptor was evaluated in CHO recombinant cells which express the human NK-1 receptor. Membra...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM242741(US10030025, Compound 2 | US10836768, Cpd no 2 | US...)
Affinity DataKi:  2.38E+4nM ΔG°:  -26.4kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK-1 receptor was evaluated in CHO recombinant cells which express the human NK-1 receptor. Membra...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM242741(US10030025, Compound 2 | US10836768, Cpd no 2 | US...)
Affinity DataKi:  2.38E+4nM ΔG°:  -26.4kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK-1 receptor was evaluated in CHO recombinant cells which express the human NK-1 receptor. Membra...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM242762(US10030025, Compound 27 | US11731974, Compound 27 ...)
Affinity DataKi: >3.00E+4nM ΔG°: >-25.8kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK-1 receptor was evaluated in CHO recombinant cells which express the human NK-1 receptor. Membra...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM50112243(CHEMBL3608682 | US10030025, Compound 28 | US108367...)
Affinity DataKi: >3.00E+4nM ΔG°: >-25.8kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK-1 receptor was evaluated in CHO recombinant cells which express the human NK-1 receptor. Membra...More data for this Ligand-Target Pair
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TargetSubstance-P receptor(Homo sapiens (Human))
University Of Arizona Tucson

LigandPNGBDBM280751((R)-4-(8-methyl-3-(3-methyl- 1,2,4-thiadiazol-5-yl...)
Affinity DataKi: >3.00E+4nM ΔG°: >-25.8kJ/molepH: 7.4 T: 2°CAssay Description:The affinity of compounds of the invention for the NK-1 receptor was evaluated in CHO recombinant cells which express the human NK-1 receptor. Membra...More data for this Ligand-Target Pair
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