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Found 34 of ph data with Target = 'Tyrosinase'
TargetTyrosinase(Homo sapiens (Human))
University Of Karachi

LigandPNGBDBM50218211(1'-(4-Methyl-benzyl)-[1,4']bipiperidinyl | CHEMBL3...)
Affinity DataIC50:  1.72E+3nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using SpectraMax 340 (Molecular Devices, CA, USA) microplate reader accord...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University Of Karachi

LigandPNGBDBM50198715((2S)-2-amino-3-(3-hydroxy-4-oxopyridin-1(4H)-yl)pr...)
Affinity DataIC50:  3.68E+3nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using SpectraMax 340 (Molecular Devices, CA, USA) microplate reader accord...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetTyrosinase(Mus musculus (Mouse))
Indian Institute Of Integrative Medicine

LigandPNGBDBM175278((E)-2,3-bis(4-Hydroxyphenyl)acrylonitrile (21))
Affinity DataIC50:  5.06E+3nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University Of Karachi

LigandPNGBDBM50218209(CHEMBL250773 | Tyrosinase Inhibitor, 3 | naphthale...)
Affinity DataIC50:  6.64E+3nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using SpectraMax 340 (Molecular Devices, CA, USA) microplate reader accord...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University Of Karachi

LigandPNGBDBM85773(Tyrosinase Inhibitor, 8)
Affinity DataIC50:  8.76E+3nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using SpectraMax 340 (Molecular Devices, CA, USA) microplate reader accord...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute Of Integrative Medicine

LigandPNGBDBM23926((E)-resveratrol | 5-[(E)-2-(4-hydroxyphenyl)etheny...)
Affinity DataIC50:  1.08E+4nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University Of Karachi

LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  1.67E+4nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using SpectraMax 340 (Molecular Devices, CA, USA) microplate reader accord...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute Of Integrative Medicine

LigandPNGBDBM175269(Trans-4-Styryl-phenol (8))
Affinity DataIC50:  1.74E+4nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University Of Karachi

LigandPNGBDBM50218210(2,2,2-trifluoro-1-(4-(piperidin-1-yl)piperidin-1-y...)
Affinity DataIC50:  1.81E+4nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using SpectraMax 340 (Molecular Devices, CA, USA) microplate reader accord...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University Of Karachi

LigandPNGBDBM85774(Tyrosinase Inhibitor, 10)
Affinity DataIC50:  1.95E+4nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using SpectraMax 340 (Molecular Devices, CA, USA) microplate reader accord...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University Of Karachi

LigandPNGBDBM50218205(1-(4-(piperidin-1-yl)piperidin-1-yl)ethanone | CHE...)
Affinity DataIC50:  2.99E+4nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using SpectraMax 340 (Molecular Devices, CA, USA) microplate reader accord...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute Of Integrative Medicine

LigandPNGBDBM175267(Trans-4-Styrylbenzonitrile (6))
Affinity DataIC50:  5.00E+4nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute Of Integrative Medicine

LigandPNGBDBM175271(Trans-1-fluoro-4-(4-methoxystyryl)benzene (10))
Affinity DataIC50:  5.00E+4nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute Of Integrative Medicine

LigandPNGBDBM175272(Trans-2-Bromo-1-methoxy-4-styryl-benzene (11))
Affinity DataIC50:  5.62E+4nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute Of Integrative Medicine

LigandPNGBDBM175263(Trans-1-Fluoro-4-styryl-benzene (2))
Affinity DataIC50:  7.94E+4nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Homo sapiens (Human))
University Of Karachi

LigandPNGBDBM50218206(1,4'-bipiperidine | 1,4'-bipiperidyl | 4-PIPERIDIN...)
Affinity DataIC50:  1.11E+5nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using SpectraMax 340 (Molecular Devices, CA, USA) microplate reader accord...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute Of Integrative Medicine

LigandPNGBDBM175275(Trans-9-Styryl-anthracene (15))
Affinity DataIC50:  1.66E+5nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute Of Integrative Medicine

LigandPNGBDBM26190(1,4-Dihydroxybenzene, XIII | 1,4-dihydroxybenzene ...)
Affinity DataIC50:  1.88E+5nMpH: 6.8 T: 2°CAssay Description:The enzyme activity was monitored by dopachrome formation at 475nm for an appropriate period.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute Of Integrative Medicine

LigandPNGBDBM175279((E)-2-(4-Hydroxyphenyl)-3-(pyridin-3-yl)acrylonitr...)
Affinity DataIC50:  2.70E+5nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute Of Integrative Medicine

LigandPNGBDBM175277((E)-3-(4-Methoxyphenyl)-2-phenylpropenal (20))
Affinity DataIC50:  2.76E+5nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute Of Integrative Medicine

LigandPNGBDBM175265(Trans-1-Bromo-4-styrylbenzene (4))
Affinity DataIC50:  2.77E+5nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute Of Integrative Medicine

LigandPNGBDBM175264(Trans-1-Chloro-4-styrylbenzene (3))
Affinity DataIC50:  3.20E+5nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute Of Integrative Medicine

LigandPNGBDBM175266(Trans-1-Nitro-4-styrylbenzene (5))
Affinity DataIC50:  3.61E+5nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute Of Integrative Medicine

LigandPNGBDBM175273(Trans-1,3-Difluoro-5-styrylbenzene (12))
Affinity DataIC50:  3.94E+5nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute Of Integrative Medicine

LigandPNGBDBM175270(Trans-1-Methoxy-4-styryl-benzene (9))
Affinity DataIC50:  4.33E+5nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute Of Integrative Medicine

LigandPNGBDBM175274(Trans-1,2,3,4,5-Pentafluoro-6-styryl-benzene (14))
Affinity DataIC50: >5.00E+5nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute Of Integrative Medicine

LigandPNGBDBM50006677(1,2,3-Trimethoxy-5-[(Z)-2-(4-methoxy-phenyl)-vinyl...)
Affinity DataIC50: >5.00E+5nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute Of Integrative Medicine

LigandPNGBDBM175262(Trans-1,2-Diphenylethene (1))
Affinity DataIC50: >5.00E+5nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute Of Integrative Medicine

LigandPNGBDBM175268(Trans-Acetic acid 4-styryl-phenyl ester (7))
Affinity DataIC50: >5.00E+5nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute Of Integrative Medicine

LigandPNGBDBM175276((E)-Methyl-3-(4-hydroxy-3-methoxyphenyl)-2-(4-meth...)
Affinity DataIC50: >5.00E+5nMpH: 6.8Assay Description:The reaction mixture contained 50 mM phosphate buffer, pH 6.8, 0.05% L-DOPA and the supernatant (tyrosinase). After incubation in the absence or pres...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute Of Integrative Medicine

LigandPNGBDBM50130191(2-Hydroxymethyl-6-(4-hydroxy-phenoxy)-tetrahydro-p...)
Affinity DataIC50:  6.25E+5nMpH: 6.8 T: 2°CAssay Description:The enzyme activity was monitored by dopachrome formation at 475nm for an appropriate period.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute Of Integrative Medicine

LigandPNGBDBM50177408(4-(hydroxymethyl)phenol | 4-Hydroxybenzyl alcohol ...)
Affinity DataIC50:  6.50E+5nMpH: 6.8 T: 2°CAssay Description:The enzyme activity was monitored by dopachrome formation at 475nm for an appropriate period.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute Of Integrative Medicine

LigandPNGBDBM87065(3HBA | 4-[4-(4-methylphenyl)sulfonyl-2-(3,4,5-trim...)
Affinity DataIC50:  9.52E+5nMpH: 6.8 T: 2°CAssay Description:The enzyme activity was monitored by dopachrome formation at 475nm for an appropriate period.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosinase(Mus musculus (Mouse))
Indian Institute Of Integrative Medicine

LigandPNGBDBM87066(2HBA | 3-[(5E)-4-keto-5-p-anisylidene-2-thioxo-thi...)
Affinity DataIC50:  2.39E+6nMpH: 6.8 T: 2°CAssay Description:The enzyme activity was monitored by dopachrome formation at 475nm for an appropriate period.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed