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Found 1592 of ph data with Target = 'Tyrosine-protein kinase BTK'
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM206362(US9260415, 113)
Affinity DataKi:  0.146nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk, Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM206354(US9260415, 105)
Affinity DataKi:  0.248nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk, Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM206355(US9260415, 106)
Affinity DataKi:  0.306nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk, Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM206360(US9260415, 111)
Affinity DataKi:  0.494nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk, Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM206366(US9260415, 117)
Affinity DataKi:  0.576nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk, Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM206356(US9260415, 107)
Affinity DataKi:  0.612nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk, Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM206359(US9260415, 110)
Affinity DataKi:  0.683nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk, Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM206350(US9260415, 101)
Affinity DataKi:  0.792nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk, Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM206351(US9260415, 102)
Affinity DataKi:  0.864nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk, Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM206363(US9260415, 114)
Affinity DataKi:  0.888nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk, Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM206353(US9260415, 104)
Affinity DataKi:  0.915nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk, Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM206367(US9260415, 118)
Affinity DataKi:  1.70nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk, Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM206361(US9260415, 112)
Affinity DataKi:  1.75nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk, Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM206364(US9260415, 115)
Affinity DataKi:  2.16nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk, Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM206365(US9260415, 116)
Affinity DataKi:  2.37nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk, Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM206357(US9260415, 108)
Affinity DataKi:  2.57nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk, Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM206358(US9260415, 109)
Affinity DataKi:  4.33nMpH: 7.5Assay Description:A generalized procedure for a standard biochemical Btk, Kinase Assay that can be used to test Formula I compounds is as follows. A master mix minus B...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM209866(PF-06651600 | US11111242, Example 5 | US2023034848...)
Affinity DataKi:  62.3nMpH: 7.5Assay Description:Assay buffer was 20 mM HEPES, pH 7.5, 10 mM MgCl2, 0.01% BSA, 1 mM DTT, 0.0005% Tween 20, and 2% DMSO. Inactivation kinetic reactions were performed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM281761(4-(2-acryloyl-1,2,3,4- tetrahydroisoquinolin- 5-yl...)
Affinity DataIC50:  0.000260nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM281762(4-(2-acryloyl-1,2,3,4- tetrahydroisoquinolin- 5-yl...)
Affinity DataIC50:  0.000300nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM281763(9-(2-acryloyl-1,2,3,4- tetrahydroisoquinolin- 5-yl...)
Affinity DataIC50:  0.000300nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM281764(5-(2-acryloyl-1,2,3,4- tetrahydroisoquinolin- 5-yl...)
Affinity DataIC50:  0.000600nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM281758(4-(2-acryloyl-1,2,3,4- tetrahydroisoquinolin- 5-yl...)
Affinity DataIC50:  0.0290nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM165960(US10604504, Example 206 | US11623921, Example 206 ...)
Affinity DataIC50:  0.0400nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM165511(US10604504, Example 168 | US11623921, Example 168 ...)
Affinity DataIC50:  0.0400nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM281750(5-(2-Acryloyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-...)
Affinity DataIC50:  0.0450nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM166569(US10604504, Example 219 | US11623921, Example 219 ...)
Affinity DataIC50:  0.0500nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM165458(US10604504, Example 136 | US11623921, Example 136 ...)
Affinity DataIC50:  0.0500nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM165330(US10604504, Example 126 | US11623921, Example 126 ...)
Affinity DataIC50:  0.0600nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM165334(US10604504, Example 128 | US11623921, Example 128 ...)
Affinity DataIC50:  0.0600nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM281746(4-(2-Acryloyl-1,2,3,4-tetrahydroisoquinolin-5-yl)-...)
Affinity DataIC50:  0.0670nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM164877(US10604504, Example 25 | US11623921, Example 25 | ...)
Affinity DataIC50:  0.0700nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM281754(US10023534, Example 13 | US10023534, Example 14)
Affinity DataIC50:  0.0730nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM281745(US10023534, Example 3 | US10023534, Example 8)
Affinity DataIC50:  0.0750nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM281745(US10023534, Example 3 | US10023534, Example 8)
Affinity DataIC50:  0.0770nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM165523(US10604504, Example 172 | US11623921, Example 172 ...)
Affinity DataIC50:  0.0800nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM164805(US10604504, Example 4 | US11623921, Example 4 | US...)
Affinity DataIC50:  0.0800nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM122415(US8729078, I-25)
Affinity DataIC50:  0.0900nMpH: 7.2Assay Description:Plates assayed are 96-well polypropylene (Greiner) and 96-well 1.2 μm hydrophilic PVDF filter plates (Millipore). Concentrations reported here a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM165995(US10604504, Example 207 | US11623921, Example 207 ...)
Affinity DataIC50:  0.0900nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM122417(US8729078, I-27)
Affinity DataIC50:  0.0900nMpH: 7.2Assay Description:Plates assayed are 96-well polypropylene (Greiner) and 96-well 1.2 μm hydrophilic PVDF filter plates (Millipore). Concentrations reported here a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM164717(US10604504, Example 160 | US11623921, Example 160 ...)
Affinity DataIC50:  0.0900nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM164638(BDBM166759 | US10604504, Example 223 | US11623921,...)
Affinity DataIC50:  0.0900nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM164773(US10604504, Example 174 | US11623921, Example 174 ...)
Affinity DataIC50:  0.0900nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM259423(US10457647, Example 22 | US11180460, Example 22 | ...)
Affinity DataIC50: <0.100nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM164793(US10604504, Example 232 | US11623921, Example 232 ...)
Affinity DataIC50:  0.100nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM166785(US10604504, Example 233 | US11623921, Example 233 ...)
Affinity DataIC50:  0.100nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM164713(US10604504, Example 95 | US11623921, Example 95 | ...)
Affinity DataIC50:  0.100nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM164717(US10604504, Example 160 | US11623921, Example 160 ...)
Affinity DataIC50:  0.100nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM166831(US10604504, Example 242 | US11623921, Example 242 ...)
Affinity DataIC50:  0.100nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM164875(US10604504, Example 23 | US11623921, Example 23 | ...)
Affinity DataIC50:  0.110nMpH: 7.4 T: 2°CAssay Description:To V-bottom 384-well plates were added test compounds, human recombinant Btk (1 nM, Invitrogen Corporation), fluoresceinated peptide (1.5 μM), A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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