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Found 9 of affinity data with PDB=2H15
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universite Montpellier Ii

LigandPNGBDBM13055(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Affinity DataKi:  2.14E+3nM ΔG°:  -32.0kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universite Montpellier Ii

LigandPNGBDBM13055(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Affinity DataKi:  2.14E+3nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 2-mediated CO2 hydration activity after 15 minsMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universite Montpellier Ii

LigandPNGBDBM13055(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Affinity DataKi:  2.14E+3nMAssay Description:Inhibition of full length human carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universite Montpellier Ii

LigandPNGBDBM13055(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Affinity DataKi:  2.14E+3nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universite Montpellier Ii

LigandPNGBDBM13055(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Affinity DataKi:  3.40E+5nMAssay Description:Inhibitory constant value for Carbonic anhydrase II in human determined in esterase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universite Montpellier Ii

LigandPNGBDBM13055(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Affinity DataKi:  3.40E+5nMAssay Description:Inhibition of human carbonic anhydrase 2 by 4-NPA hydrolysis assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universite Montpellier Ii

LigandPNGBDBM13055(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Affinity DataKi:  6.50E+5nMAssay Description:Inhibitory constant value for Carbonic anhydrase II in human determined in pH-shift assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universite Montpellier Ii

LigandPNGBDBM13055(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Affinity DataKd:  2.50E+4nMpH: 7.5Assay Description:Binding affinity to human carbonic anhydrase 2 in presence of 10 mM HEPES and 100 uM Na2SO4 at pH 7.5 by ThermoFluor methodMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universite Montpellier Ii

LigandPNGBDBM13055(CHEMBL283695 | Compound 8 | Topiramate Sulfamide A...)
Affinity DataKd:  2.50E+4nMAssay Description:Binding affinity to human CA2 by ThermoFluor assayMore data for this Ligand-Target Pair