Compile Data Set for Download or QSAR
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Found 14 of affinity data with PDB=3FW3
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Nicox Research Institute

Curated by ChEMBL
LigandPNGBDBM10884((2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)
Affinity DataKi:  43nMAssay Description:Inhibition of human carbonic anhydrase 4 by CO2 hydrase stopped flow assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Nicox Research Institute

Curated by ChEMBL
LigandPNGBDBM10884((2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)
Affinity DataKi:  43nMAssay Description:Inhibition of cloned isozyme, human carbonic anhydrase IVMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Nicox Research Institute

Curated by ChEMBL
LigandPNGBDBM10884((2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)
Affinity DataKi:  8.50E+3nMAssay Description:Inhibition of human full length carbonic anhydrase 4 by stopped flow CO2 hydrase assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Nicox Research Institute

Curated by ChEMBL
LigandPNGBDBM10884((2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)
Affinity DataKi:  8.50E+3nM ΔG°:  -28.7kJ/molepH: 7.5 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Nicox Research Institute

Curated by ChEMBL
LigandPNGBDBM10884((2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)
Affinity DataKi:  8.50E+3nMAssay Description:Inhibition of human CA4 by CO2 hydration assayMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Nicox Research Institute

Curated by ChEMBL
LigandPNGBDBM10884((2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)
Affinity DataKi:  8.50E+3nMAssay Description:Inhibition of human carbonic anhydrase 4More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Nicox Research Institute

Curated by ChEMBL
LigandPNGBDBM10884((2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)
Affinity DataKi:  8.53E+3nMAssay Description:Inhibitory activity against human carbonic anhydrase IV (hCAIV)More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Nicox Research Institute

Curated by ChEMBL
LigandPNGBDBM26992(CHEMBL183495 | SO4(2-) | SODIUM SULFATE | sulfate ...)
Affinity DataKi:  9.00E+6nMAssay Description:Inhibition constant of anion against human carbonic anhydrase isozyme hCA IVMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Nicox Research Institute

Curated by ChEMBL
LigandPNGBDBM26992(CHEMBL183495 | SO4(2-) | SODIUM SULFATE | sulfate ...)
Affinity DataKi:  9.00E+6nMAssay Description:Inhibitory activity against human Carbonic anhydrase IVMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Nicox Research Institute

Curated by ChEMBL
LigandPNGBDBM26992(CHEMBL183495 | SO4(2-) | SODIUM SULFATE | sulfate ...)
Affinity DataKi:  9.00E+6nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Nicox Research Institute

Curated by ChEMBL
LigandPNGBDBM26992(CHEMBL183495 | SO4(2-) | SODIUM SULFATE | sulfate ...)
Affinity DataKi:  9.00E+6nMAssay Description:Inhibition of human carbonic anhydrase 4 by Lineweaver-Burk curvesMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Nicox Research Institute

Curated by ChEMBL
LigandPNGBDBM26992(CHEMBL183495 | SO4(2-) | SODIUM SULFATE | sulfate ...)
Affinity DataKi:  4.40E+7nMAssay Description:Inhibitory constant against carbonic anhydrase IVMore data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Nicox Research Institute

Curated by ChEMBL
LigandPNGBDBM10884((2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)
Affinity DataIC50:  32nMAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Homo sapiens (Human))
Nicox Research Institute

Curated by ChEMBL
LigandPNGBDBM10884((2S,4S)-4-(ethylamino)-2-methyl-1,1-dioxo-2H,3H,4H...)
Affinity DataIC50:  43nMAssay Description:Inhibition of carbonic anhydrase 4More data for this Ligand-Target Pair