Compile Data Set for Download or QSAR
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Found 3 of affinity data with PDB=5NAR
TargetComplement factor D(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM60517(US9085555, 124)
Affinity DataIC50:  500nMpH: 7.5 T: 2°CAssay Description:Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compound at vario...More data for this Ligand-Target Pair
TargetComplement factor D(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM60517(US9085555, 124)
Affinity DataIC50:  500nMAssay Description:Inhibition of recombinant human complement factor D catalytic domain using Z-Lys-thiobenzylester as substrate preincubated for 1 hr followed by subst...More data for this Ligand-Target Pair
TargetComplement factor D(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM60517(US9085555, 124)
Affinity DataIC50:  800nMAssay Description:Inhibition of recombinant human complement factor D catalytic domain (G24 to A253 residues) expressed in expressed in Escherichia coli(Rosetta) using...More data for this Ligand-Target Pair