Compile Data Set for Download or QSAR
maximum 50k data
Found 28 of ec50 data for polymerid = 10444,49001048,49001049
TargetThromboxane A2 receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283059((Z)-7-[(1R,5S,6R,7R)-7-((E)-3-Hydroxy-oct-1-enyl)-...)
Affinity DataEC50:  0.230nMAssay Description:Activity of the compound against thromboxane A2 receptor evaluated by contraction of isolated rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane A2 receptor(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM240746(US9422273, 12d)
Affinity DataEC50:  0.300nMpH: 7.4 T: 2°CAssay Description:Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThromboxane A2 receptor(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM240745(US9422273, 12c)
Affinity DataEC50: <1nMpH: 7.4 T: 2°CAssay Description:Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThromboxane A2 receptor(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM240744(US9422273, 12a)
Affinity DataEC50: <1nMpH: 7.4 T: 2°CAssay Description:Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThromboxane A2 receptor(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM62356(US9422273, 12b)
Affinity DataEC50: <1nMpH: 7.4 T: 2°CAssay Description:Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetThromboxane A2 receptor(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM240747(US9422273, 12e)
Affinity DataEC50: >1nMpH: 7.4 T: 2°CAssay Description:Ca2+ signaling studies were performed using a FLIPR TETRA system (Molecular Devices, Sunnyvale, Calif., USA) in the 384-format. This is a high-throug...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThromboxane A2 receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283057((1R,5S,6R,7R)-6-((Z)-7-Hydroxy-hept-2-enyl)-7-((E)...)
Affinity DataEC50:  1nMAssay Description:Activity of the compound against thromboxane A2 receptor evaluated by contraction of isolated rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane A2 receptor(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM238326(US9394273, 15)
Affinity DataEC50: <10nMpH: 7.4Assay Description:Calciium Signal Studies of the Flipr. Cells were seeded at a density of 5×104 cells per well in BiocoatiŽ Poly-D-lysine-coated black-wall, clear-bott...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThromboxane A2 receptor(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM50090136((Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((E)-(R)-3-hy...)
Affinity DataEC50:  24nMAssay Description:Functional activity in RAT-1cells, transiently-transfected with human TP-receptor (% of control ligand, [3H]-U-46,619=95%)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM50283059((Z)-7-[(1R,5S,6R,7R)-7-((E)-3-Hydroxy-oct-1-enyl)-...)
Affinity DataEC50:  24nMAssay Description:Activity of the compound against thromboxane A2 receptor evaluated by aggregation of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane A2 receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283060((Z)-7-[(1R,5S,6R,7R)-7-((E)-3-Hydroxy-oct-1-enyl)-...)
Affinity DataEC50:  58nMAssay Description:Activity of the compound against thromboxane A2 receptor evaluated by contraction of isolated rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane A2 receptor(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM238319(US9394273, 10 | US9394273, 8 | US9394273, 9)
Affinity DataEC50:  100nMpH: 7.4Assay Description:Calciium Signal Studies of the Flipr. Cells were seeded at a density of 5×104 cells per well in BiocoatiŽ Poly-D-lysine-coated black-wall, clear-bott...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThromboxane A2 receptor(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM238319(US9394273, 10 | US9394273, 8 | US9394273, 9)
Affinity DataEC50:  108nMpH: 7.4Assay Description:Calciium Signal Studies of the Flipr. Cells were seeded at a density of 5×104 cells per well in BiocoatiŽ Poly-D-lysine-coated black-wall, clear-bott...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThromboxane A2 receptor(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM238322(US9394273, 11 | US9394273, 12)
Affinity DataEC50:  218nMpH: 7.4Assay Description:Calciium Signal Studies of the Flipr. Cells were seeded at a density of 5×104 cells per well in BiocoatiŽ Poly-D-lysine-coated black-wall, clear-bott...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThromboxane A2 receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50283058((Z)-7-[(1R,5S,6R,7R)-7-((E)-3-Hydroxy-oct-1-enyl)-...)
Affinity DataEC50:  324nMAssay Description:Activity of the compound against thromboxane A2 receptor evaluated by contraction of isolated rat thoracic aortaMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane A2 receptor(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM50035622((5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,...)
Affinity DataEC50:  1.40E+3nMAssay Description:Functional activity in RAT-1cells, transiently-transfected with human TP-receptor (% of control ligand, [3H]-U-46,619=95%)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM50090133((Z)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E)-(S)-3-hy...)
Affinity DataEC50:  2.10E+3nMAssay Description:Functional activity in RAT-1cells, transiently-transfected with human TP-receptor (% of control ligand, [3H]-U-46,619=50%)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM50085910((Z)-7-{(1R,2R,3R,5S)-2-[(E)-(R)-4-(3-Chloro-phenox...)
Affinity DataEC50:  2.40E+3nMAssay Description:Functional activity in RAT-1cells, transiently-transfected with human TP-receptor (% of control ligand, [3H]-U-46,619=100%)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM238334(US9394273, 23 | US9394273, 24)
Affinity DataEC50:  2.45E+3nMpH: 7.4Assay Description:Calciium Signal Studies of the Flipr. Cells were seeded at a density of 5×104 cells per well in BiocoatiŽ Poly-D-lysine-coated black-wall, clear-bott...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThromboxane A2 receptor(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM50283060((Z)-7-[(1R,5S,6R,7R)-7-((E)-3-Hydroxy-oct-1-enyl)-...)
Affinity DataEC50:  3.11E+3nMAssay Description:Activity of the compound against thromboxane A2 receptor evaluated by aggregation of human plateletsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetThromboxane A2 receptor(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM238318(US9394273, 7)
Affinity DataEC50:  4.83E+3nMpH: 7.4Assay Description:Calciium Signal Studies of the Flipr. Cells were seeded at a density of 5×104 cells per well in BiocoatiŽ Poly-D-lysine-coated black-wall, clear-bott...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThromboxane A2 receptor(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM238330(US9394273, 19 | US9394273, 20)
Affinity DataEC50:  5.60E+3nMpH: 7.4Assay Description:Calciium Signal Studies of the Flipr. Cells were seeded at a density of 5×104 cells per well in BiocoatiŽ Poly-D-lysine-coated black-wall, clear-bott...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThromboxane A2 receptor(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM238316(US9394273, 5 | US9394273, 6)
Affinity DataEC50:  7.19E+3nMpH: 7.4Assay Description:Calciium Signal Studies of the Flipr. Cells were seeded at a density of 5×104 cells per well in BiocoatiŽ Poly-D-lysine-coated black-wall, clear-bott...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetThromboxane A2 receptor(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM50085911(7-{(1R,2R,3R,5S)-2-[(R)-4-(3-Chloro-phenoxy)-3-hyd...)
Affinity DataEC50:  8.00E+3nMAssay Description:Functional activity in RAT-1cells, transiently-transfected with human TP-receptor (% of control ligand, [3H]-U-46,619=90%)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM50090137(7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((R)-3-hydroxy-4,...)
Affinity DataEC50: >2.00E+4nMAssay Description:Functional activity in RAT-1cells, transiently-transfected with human TP-receptor (% of control ligand, [3H]-U-46,619<20%)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM50090140(7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(R)-3-hydroxy-5-...)
Affinity DataEC50: >2.00E+4nMAssay Description:Functional activity in RAT-1cells, transiently-transfected with human FP-receptor (% of control ligand, fluprostenol=100%)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM50085914(7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((S)-3-hydroxy-oc...)
Affinity DataEC50:  3.00E+4nMAssay Description:Functional activity in RAT-1cells, transiently-transfected with human TP-receptor (% of control ligand, [3H]-U-46,619=100%)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Allergan

US Patent
LigandPNGBDBM50027852(CHEMBL3338677)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at thromboxane A2 receptor (unknown origin) expressed in HEK293-EBNA cells after 3 mins by calcium flux/FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed