TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
Uppsala University
Curated by ChEMBL
Uppsala University
Curated by ChEMBL
Affinity DataEC50: 15nMAssay Description:Modulator activity at rat Nav1.4 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-elec...More data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
Uppsala University
Curated by ChEMBL
Uppsala University
Curated by ChEMBL
Affinity DataEC50: 15nMAssay Description:Modulator activity at rat Nav1.4 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-elec...More data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
Uppsala University
Curated by ChEMBL
Uppsala University
Curated by ChEMBL
Affinity DataEC50: 46nMAssay Description:Modulator activity at rat Nav1.4 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-elec...More data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
Uppsala University
Curated by ChEMBL
Uppsala University
Curated by ChEMBL
Affinity DataEC50: 146nMAssay Description:Modulator activity at rat Nav1.4 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-elec...More data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
Uppsala University
Curated by ChEMBL
Uppsala University
Curated by ChEMBL
Affinity DataEC50: 150nMAssay Description:Modulator activity at rat Nav1.4 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-elec...More data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
Uppsala University
Curated by ChEMBL
Uppsala University
Curated by ChEMBL
Affinity DataEC50: 811nMAssay Description:Modulator activity at rat Nav1.4 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-elec...More data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
Uppsala University
Curated by ChEMBL
Uppsala University
Curated by ChEMBL
Affinity DataEC50: 1.15E+3nMAssay Description:Modulator activity at rat Nav1.4 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-elec...More data for this Ligand-Target Pair
Affinity DataEC50: 1.70E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 1.91E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 2.29E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 2.40E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 2.69E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 2.88E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 3.02E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 3.02E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 3.02E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 3.02E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 3.72E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 3.98E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 4.50E+3nMpH: 7.35 T: 2°CAssay Description:All experiments were conducted at room temperature (22-24° C.) with an EPC-10 amplifier and Pulse software (HEKA, Lambrecht/Pfalz, Germany) in the wh...More data for this Ligand-Target Pair
Affinity DataEC50: 4.68E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 5.75E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 5.75E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 7.08E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 7.94E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 9.12E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 1.00E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 1.12E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 1.51E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 1.58E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 1.74E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 1.95E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 2.29E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 2.29E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 2.34E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 2.69E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 2.82E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 3.16E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 4.07E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 6.76E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 6.76E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+5nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 2.09E+5nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 2.19E+5nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 2.24E+5nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 2.34E+5nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
Affinity DataEC50: 2.75E+5nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair