Compile Data Set for Download or QSAR
maximum 50k data
Found 52 of ec50 data for polymerid = 347,7989,50006958
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50582058(CHEMBL5093878)
Affinity DataEC50:  15nMAssay Description:Modulator activity at rat Nav1.4 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-elec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50582057(CHEMBL5077579)
Affinity DataEC50:  15nMAssay Description:Modulator activity at rat Nav1.4 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-elec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50582059(CHEMBL5082582)
Affinity DataEC50:  46nMAssay Description:Modulator activity at rat Nav1.4 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-elec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50582054(CHEMBL5091679)
Affinity DataEC50:  146nMAssay Description:Modulator activity at rat Nav1.4 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-elec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50582056(CHEMBL5091623)
Affinity DataEC50:  150nMAssay Description:Modulator activity at rat Nav1.4 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-elec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50582060(CHEMBL5084333)
Affinity DataEC50:  811nMAssay Description:Modulator activity at rat Nav1.4 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-elec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50135878((R)-1-Phenyl-2-o-tolyloxy-ethylamine | (R)-1-pheny...)
Affinity DataEC50:  1.00E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Rattus norvegicus (Rat))
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50582055(CHEMBL5083412)
Affinity DataEC50:  1.15E+3nMAssay Description:Modulator activity at rat Nav1.4 expressed in Xenopus laevis oocytes assessed as elicitation in sodium current measured after 1 to 4 days by two-elec...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413853(CHEMBL485004)
Affinity DataEC50:  1.70E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413870(CHEMBL444700)
Affinity DataEC50:  1.91E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413854(CHEMBL486721)
Affinity DataEC50:  2.29E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413858(CHEMBL487338)
Affinity DataEC50:  2.40E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413869(CHEMBL448542)
Affinity DataEC50:  2.69E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413860(CHEMBL501561)
Affinity DataEC50:  2.88E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413862(CHEMBL486528)
Affinity DataEC50:  3.02E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50135880((S)-2-(2,6-Dimethyl-phenoxy)-1-phenyl-ethylamine |...)
Affinity DataEC50:  3.02E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50135886((R)-2-(2,6-Dimethyl-phenoxy)-1-phenyl-ethylamine |...)
Affinity DataEC50:  3.02E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50135873((S)-2-(4-Chloro-phenoxy)-1-phenyl-ethylamine | (S)...)
Affinity DataEC50:  3.02E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413859(CHEMBL486315)
Affinity DataEC50:  3.72E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50135874((R)-2-Phenoxy-1-phenyl-ethylamine | (R)-2-phenoxy-...)
Affinity DataEC50:  3.98E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM168436(US9675591, SKA-19)
Affinity DataEC50:  4.50E+3nMpH: 7.35 T: 2°CAssay Description:All experiments were conducted at room temperature (22-24° C.) with an EPC-10 amplifier and Pulse software (HEKA, Lambrecht/Pfalz, Germany) in the wh...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413868(CHEMBL452986)
Affinity DataEC50:  4.68E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413856(CHEMBL446777)
Affinity DataEC50:  5.75E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413857(CHEMBL474672)
Affinity DataEC50:  5.75E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413867(CHEMBL483784)
Affinity DataEC50:  7.08E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50135882((S)-2-(4-Chloro-2,6-dimethyl-phenoxy)-1-phenyl-eth...)
Affinity DataEC50:  7.94E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413842(CHEMBL473498)
Affinity DataEC50:  9.12E+3nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413852(CHEMBL485003)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50135881((R)-2-(4-Chloro-phenoxy)-1-phenyl-ethylamine | (R)...)
Affinity DataEC50:  1.00E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413841(CHEMBL472884)
Affinity DataEC50:  1.12E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413843(CHEMBL502686)
Affinity DataEC50:  1.20E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50135885((R)-2-(4-Chloro-2-methyl-phenoxy)-1-phenyl-ethylam...)
Affinity DataEC50:  1.51E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50135879((S)-2-Phenoxy-1-phenyl-ethylamine | (S)-2-phenoxy-...)
Affinity DataEC50:  1.58E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413866(CHEMBL485647)
Affinity DataEC50:  1.74E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50135877((R)-2-(4-Chloro-2,6-dimethyl-phenoxy)-1-phenyl-eth...)
Affinity DataEC50:  1.95E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50135883((2R)-1-(2,6-dimethylphenoxy)propan-2-amine | (R)-1...)
Affinity DataEC50:  2.29E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413861(CHEMBL486414)
Affinity DataEC50:  2.29E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413865(CHEMBL468775)
Affinity DataEC50:  2.34E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50135884((S)-1-(2,6-dimethylphenoxy)propan-2-amine | (S)-2-...)
Affinity DataEC50:  2.69E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413846(CHEMBL473706)
Affinity DataEC50:  2.82E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413851(CHEMBL519199)
Affinity DataEC50:  3.16E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413844(CHEMBL473499)
Affinity DataEC50:  4.07E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413848(CHEMBL484996)
Affinity DataEC50:  6.76E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413845(CHEMBL473705)
Affinity DataEC50:  6.76E+4nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413850(CHEMBL485002)
Affinity DataEC50:  2.00E+5nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413863(CHEMBL2021482)
Affinity DataEC50:  2.09E+5nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413847(CHEMBL484981)
Affinity DataEC50:  2.19E+5nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50291989((S)-2-Amino-N-(2,6-dimethyl-phenyl)-propionamide(t...)
Affinity DataEC50:  2.24E+5nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50413864(CHEMBL2021481)
Affinity DataEC50:  2.34E+5nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 4 subunit alpha(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50291990((R)-2-Amino-N-(2,6-dimethyl-phenyl)-propionamide(t...)
Affinity DataEC50:  2.75E+5nMAssay Description:Inhibition of Nav1.4 ion channel assessed as reduction in cumulative sodium currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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