Compile Data Set for Download or QSAR
maximum 50k data
Found 45 of ec50 data for polymerid = 4020
LigandPNGBDBM32573(CHEMBL427896 | arylsulfonylpiperazine, 45)
Affinity DataIC50:  3nM EC50:  57nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
LigandPNGBDBM32538(arylsulfonylpiperazine, 10)
Affinity DataIC50:  4nM EC50:  201nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32550(arylsulfonylpiperazine, 22)
Affinity DataIC50:  7nM EC50:  241nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32561(arylsulfonylpiperazine, 33)
Affinity DataIC50:  10nM EC50:  247nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32566(arylsulfonylpiperazine, 38)
Affinity DataIC50:  3nM EC50:  315nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32547(arylsulfonylpiperazine, 19)
Affinity DataIC50:  13nM EC50:  329nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32542(arylsulfonylpiperazine, 14)
Affinity DataIC50:  19nM EC50:  456nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32575(arylsulfonylpiperazine, 1)
Affinity DataIC50:  16nM EC50:  461nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32535(arylsulfonylpiperazine, 7)
Affinity DataIC50:  18nM EC50:  510nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32540(arylsulfonylpiperazine, 12)
Affinity DataIC50:  14nM EC50:  518nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32574(arylsulfonylpiperazine, 46)
Affinity DataIC50:  29nM EC50:  527nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
LigandPNGBDBM32546(arylsulfonylpiperazine, 18)
Affinity DataIC50:  13nM EC50:  547nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32537(arylsulfonylpiperazine, 9)
Affinity DataIC50:  15nM EC50:  556nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32572(arylsulfonylpiperazine, 44)
Affinity DataIC50:  9nM EC50:  569nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32534(arylsulfonylpiperazine, 6)
Affinity DataIC50:  20nM EC50:  574nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32545(arylsulfonylpiperazine, 17)
Affinity DataIC50:  74nM EC50:  603nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32536(arylsulfonylpiperazine, 8)
Affinity DataIC50:  16nM EC50:  613nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32567(arylsulfonylpiperazine, 39)
Affinity DataIC50:  9nM EC50:  632nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32570(arylsulfonylpiperazine, 42)
Affinity DataIC50:  62nM EC50:  638nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32539(arylsulfonylpiperazine, 11)
Affinity DataIC50:  46nM EC50:  667nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32557(arylsulfonylpiperazine, 29)
Affinity DataIC50:  32nM EC50:  702nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32530(arylsulfonylpiperazine, 2)
Affinity DataIC50:  45nM EC50:  724nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32541(arylsulfonylpiperazine, 13)
Affinity DataIC50:  14nM EC50:  727nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32571(arylsulfonylpiperazine, 43)
Affinity DataIC50:  11nM EC50:  762nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32560(arylsulfonylpiperazine, 32)
Affinity DataIC50:  37nM EC50:  839nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32543(arylsulfonylpiperazine, 15)
Affinity DataIC50:  37nM EC50:  922nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32556(arylsulfonylpiperazine, 28)
Affinity DataIC50:  15nM EC50:  971nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32544(arylsulfonylpiperazine, 16)
Affinity DataIC50:  50nM EC50:  978nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32569(arylsulfonylpiperazine, 41)
Affinity DataIC50:  58nM EC50: >1.00E+3nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32568(arylsulfonylpiperazine, 40)
Affinity DataIC50:  17nM EC50: >1.00E+3nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32565(arylsulfonylpiperazine, 37)
Affinity DataIC50:  234nM EC50: >1.00E+3nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32564(arylsulfonylpiperazine, 36)
Affinity DataIC50:  42nM EC50: >1.00E+3nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32563(arylsulfonylpiperazine, 35)
Affinity DataIC50:  390nM EC50: >1.00E+3nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32562(arylsulfonylpiperazine, 34)
Affinity DataIC50:  87nM EC50: >1.00E+3nMAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32559(arylsulfonylpiperazine, 31)
Affinity DataIC50:  106nM EC50: >1.00E+3nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32558(arylsulfonylpiperazine, 30)
Affinity DataIC50:  95nM EC50: >1.00E+3nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32555(arylsulfonylpiperazine, 27)
Affinity DataIC50:  628nM EC50: >1.00E+3nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32554(arylsulfonylpiperazine, 26)
Affinity DataIC50:  291nM EC50: >1.00E+3nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32553(arylsulfonylpiperazine, 25)
Affinity DataIC50:  117nM EC50: >1.00E+3nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32552(arylsulfonylpiperazine, 24)
Affinity DataIC50:  152nM EC50: >1.00E+3nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32551(arylsulfonylpiperazine, 23)
Affinity DataIC50: >1.00E+3nM EC50: >1.00E+3nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32549(arylsulfonylpiperazine, 21)
Affinity DataIC50:  64nM EC50: >1.00E+3nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32548(arylsulfonylpiperazine, 20)
Affinity DataIC50:  55nM EC50: >1.00E+3nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32531(phenylcarbonyl piperazine, 3)
Affinity DataIC50:  262nM EC50: >1.00E+3nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM32533(benzyl piperazine, 5)
Affinity DataIC50:  550nM EC50:  1.93E+3nMpH: 7.2 T: 2°CAssay Description:Enzyme assays were performed using purified recombinant human 11beta-HSD1. The fractional conversion of cortisone to cortisol was used to determine e...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed