Affinity DataEC50: >1nMAssay Description:Adenosine A1 receptor mediated negative chronotropic activity in spontaneously beating rat atriaMore data for this Ligand-Target Pair
Affinity DataEC50: >1nMAssay Description:Adenosine A1 receptor mediated negative chronotropic activity in spontaneously beating rat atriaMore data for this Ligand-Target Pair
Affinity DataEC50: >1nMAssay Description:Adenosine A1 receptor mediated negative chronotropic activity in spontaneously beating rat atriaMore data for this Ligand-Target Pair
Affinity DataEC50: >1nMAssay Description:Adenosine A1 receptor mediated negative chronotropic activity in spontaneously beating rat atriaMore data for this Ligand-Target Pair
Affinity DataEC50: >1nMAssay Description:Adenosine A1 receptor mediated negative chronotropic activity in spontaneously beating rat atriaMore data for this Ligand-Target Pair
Affinity DataEC50: >1nMAssay Description:Adenosine A1 receptor mediated negative chronotropic activity in spontaneously beating rat atriaMore data for this Ligand-Target Pair
Affinity DataEC50: >1nMAssay Description:Adenosine A1 receptor mediated negative chronotropic activity in spontaneously beating rat atriaMore data for this Ligand-Target Pair
Affinity DataEC50: >1nMAssay Description:Adenosine A1 receptor mediated negative chronotropic activity in spontaneously beating rat atriaMore data for this Ligand-Target Pair
Affinity DataEC50: >1nMAssay Description:Adenosine A1 receptor mediated negative chronotropic activity in spontaneously beating rat atriaMore data for this Ligand-Target Pair
Affinity DataEC50: >1nMAssay Description:Adenosine A1 receptor mediated negative chronotropic activity in spontaneously beating rat atriaMore data for this Ligand-Target Pair
Affinity DataEC50: >1nMAssay Description:Adenosine A1 receptor mediated negative chronotropic activity in spontaneously beating rat atriaMore data for this Ligand-Target Pair
Affinity DataEC50: 1.70nMAssay Description:Agonist activity at rat A1A adenosine receptor expressed in CHO-K1 cell membranes incubated for 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5.40nMAssay Description:Prolongation of the stimulus-QRS interval by 50% of the maximum response at the Adenosine A1 receptor in langendorff guinea pig heart preparationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 6.70nMAssay Description:Agonist activity at rat A1A adenosine receptor expressed in CHO-K1 cell membranes incubated for 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 7.90nMAssay Description:Agonist activity at adenosine A1 receptor in pig cortical membrane assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 8.20nMAssay Description:Negative chronotropic activity via A1 Adenosine receptor was tested in spontaneously beating rat atriaMore data for this Ligand-Target Pair
Affinity DataEC50: 8.20nMAssay Description:Activitty at Adenosine A1 receptor of rat atriaMore data for this Ligand-Target Pair
Affinity DataEC50: >10nMAssay Description:Activitty at Adenosine A1 receptor of rat atriaMore data for this Ligand-Target Pair
Affinity DataEC50: 12.6nMAssay Description:Prolongation of the stimulus-QRS interval by 50% of the maximum response at the adenosine A1 receptor in langendorff guinea pig heart preparationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 13.3nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding to rat brain membranes by adenosine A1 receptor activationMore data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Effective concentration for [35S]GTP-gamma-S, binding to adenosine A1 receptor in rat brain membranesMore data for this Ligand-Target Pair
Affinity DataEC50: 16.9nMAssay Description:Agonist activity at adenosine A1 receptor in rat cortical membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:[S]GTP gamma-S binding against adenosine A1 receptor in rat brainMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Mus musculus)
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
National Institute Of Diabetes And Digestive And Kidney Diseases
Curated by ChEMBL
Affinity DataEC50: 18nMAssay Description:Agonist activity at mouse adenosine A1 receptor expressed in HEK293 cell membranes assessed as inhibition of forskolin-stimulated cAMP production pre...More data for this Ligand-Target Pair
Affinity DataEC50: 18.3nMAssay Description:Agonist activity at adenosine A1 receptor in pig cortical membrane assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding to adenosine A1 receptor of rat cerebral cortical membraneMore data for this Ligand-Target Pair
Affinity DataEC50: 26nMAssay Description:Effective concentration for [35S]GTP-gamma-S, binding to adenosine A1 receptor in rat brain membranesMore data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding to rat brain membranes by adenosine A1 receptor activationMore data for this Ligand-Target Pair
Affinity DataEC50: 31.6nMAssay Description:Agonist activity at adenosine A1 receptor in pig cortical membrane assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 33.9nMAssay Description:Prolongation of the stimulus-QRS interval by 50% of the maximum response at the Adenosine A1 receptor in langendorff guinea pig heart preparationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 41nMAssay Description:Binding affinity against adenosine A1 receptor using [3H]CPX in guinea pig DDT membraneMore data for this Ligand-Target Pair
Affinity DataEC50: 55nMAssay Description:Negative chronotropic activity via A1 Adenosine receptor was tested in spontaneously beating rat atriaMore data for this Ligand-Target Pair
Affinity DataEC50: 55nMAssay Description:Adenosine A1 receptor mediated negative chronotropic activity in spontaneously beating rat atriaMore data for this Ligand-Target Pair
Affinity DataEC50: 55nMAssay Description:Activitty at Adenosine A1 receptor of rat atriaMore data for this Ligand-Target Pair
Affinity DataEC50: 63.1nMAssay Description:Prolongation of the stimulus-QRS interval by 50% of the maximum response at the Adenosine A1 receptor in langendorff guinea pig heart preparationChecked by AuthorMore data for this Ligand-Target Pair
Affinity DataEC50: 84nMAssay Description:Negative chronotropic activity via A1 Adenosine receptor was tested in spontaneously beating rat atriaMore data for this Ligand-Target Pair
Affinity DataEC50: 87nMAssay Description:[S]GTP gamma-S binding against adenosine A1 receptor in rat brainMore data for this Ligand-Target Pair
Affinity DataEC50: 99nMAssay Description:Effective concentration for [35S]GTP-gamma-S, binding to adenosine A1 receptor in rat brain membranesMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding to adenosine A1 receptor of rat cerebral cortical membraneMore data for this Ligand-Target Pair
Affinity DataEC50: >100nMAssay Description:[S]GTP gamma-S binding against adenosine A1 receptor in rat brainMore data for this Ligand-Target Pair
Affinity DataEC50: 110nMAssay Description:Negative chronotropic activity via A1 Adenosine receptor was tested in spontaneously beating rat atriaMore data for this Ligand-Target Pair
Affinity DataEC50: 127nMAssay Description:Effective concentration for [35S]GTP-gamma-S, binding to adenosine A1 receptor in rat brain membranesMore data for this Ligand-Target Pair
Affinity DataEC50: 145nMAssay Description:Stimulation of [35S]GTP-gamma-S, binding to adenosine A1 receptor of rat cerebral cortical membraneMore data for this Ligand-Target Pair
Affinity DataEC50: 153nMAssay Description:Negative chronotropic activity via A1 Adenosine receptor was tested in spontaneously beating rat atriaMore data for this Ligand-Target Pair
Affinity DataEC50: 164nMAssay Description:Functional activity against adenosine A1 receptor from rat atria.More data for this Ligand-Target Pair
Affinity DataEC50: 165nMAssay Description:Agonist activity at adenosine A1 receptor in pig cortical membrane assessed as stimulation of GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 167nMAssay Description:Negative chronotropic activity via A1 Adenosine receptor was tested in spontaneously beating rat atriaMore data for this Ligand-Target Pair
Affinity DataEC50: 167nMAssay Description:Functional activity against adenosine A1 receptor from rat atria.More data for this Ligand-Target Pair
Affinity DataEC50: 189nMAssay Description:Effective concentration for [35S]GTP-gamma-S, binding to adenosine A1 receptor in rat brain membranesMore data for this Ligand-Target Pair
Affinity DataEC50: 191nMAssay Description:Prolongation of the stimulus-QRS interval by 50% of the maximum response at the adenosine A1 receptor in langendorff guinea pig heart preparationChecked by AuthorMore data for this Ligand-Target Pair