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Found 3 of ec50 data for polymerid = 50004541
TargetSerine palmitoyltransferase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50461646(CHEBI:582124 | Myriocin)
Affinity DataEC50:  50nMAssay Description:Inhibition of SPT1 in human MCF7 cells assessed as suppression of 14C-serine incorporation into ceramide incubated for 2 hrs in presence of 4-HPRMore data for this Ligand-Target Pair
TargetSerine palmitoyltransferase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50535848(CHEMBL4584997)
Affinity DataEC50:  977nMAssay Description:Inhibition of SPT1 in human MCF7 cells assessed as suppression of 14C-serine incorporation into ceramide incubated for 2 hrs in presence of 4-HPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine palmitoyltransferase 1(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50535847(CHEMBL4541898)
Affinity DataEC50:  4.22E+3nMAssay Description:Inhibition of SPT1 in human MCF7 cells assessed as suppression of 14C-serine incorporation into ceramide incubated for 2 hrs in presence of 4-HPRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed