TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 9nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 10nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 11nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 15nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 15nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 16nMAssay Description:Inhibition of [3H]-U-69,593 binding to Opioid receptor kappa 1More data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 18nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 19nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 19nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 21nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 21nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 22nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 22nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 22nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 24nMAssay Description:Inhibition of [3H]-FPP incorporation into H-ras CVLS by farnesyltransferaseMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 24nMAssay Description:Inhibition of [3H]-U-69,593 binding to Opioid receptor kappa 1More data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 24nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 24nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 24nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 24nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 27nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 29nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 30nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 30nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 30nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 30nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 32nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 32nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 33nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 33nMAssay Description:Inhibition of [3H]-U-69,593 binding to Opioid receptor kappa 1More data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 33nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 36nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 37nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 40nMAssay Description:Inhibition of [3H]-FPP incorporation into H-ras CVLS by farnesyltransferaseMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 43nMAssay Description:Binding affinity against delta opioid receptor in mouse hot plate testMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 46nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 46nMAssay Description:Inhibition of [3H]-FPP incorporation into H-ras CVLS by farnesyltransferaseMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 46nMAssay Description:Inhibition of [3H]-U-69,593 binding to Opioid receptor kappa 1More data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 52nMAssay Description:Inhibition of [3H]-FPP incorporation into H-ras CVLS by farnesyltransferaseMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 52nMAssay Description:Inhibition of [3H]-U-69,593 binding to Opioid receptor kappa 1More data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 54nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 54nMAssay Description:Inhibition of [3H]-U-69,593 binding to Opioid receptor kappa 1More data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 54nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 58nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 59nMAssay Description:Inhibition of [3H]-U-69,593 binding to Opioid receptor kappa 1More data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 65nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 66nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 67nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 68nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetProbable G-protein coupled receptor 139(Homo sapiens (Human))
Takeda California
Curated by ChEMBL
Takeda California
Curated by ChEMBL
Affinity DataEC50: 77nMAssay Description:Agonist activity at human GPR139 expressed in CHO-TRex cells assessed as stimulation of calcium signalling incubated for 15 mins by FLIPR assayMore data for this Ligand-Target Pair