TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Tanabe Seiyaku
Curated by ChEMBL
Tanabe Seiyaku
Curated by ChEMBL
Affinity DataEC50: 7.90nMAssay Description:Relaxant effect on isolated rabbit corpus cavernosumMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Tanabe Seiyaku
Curated by ChEMBL
Tanabe Seiyaku
Curated by ChEMBL
Affinity DataEC50: 8.70nMAssay Description:Relaxant effect on isolated rabbit corpus cavernosumMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Tanabe Seiyaku
Curated by ChEMBL
Tanabe Seiyaku
Curated by ChEMBL
Affinity DataEC50: 9.5nMAssay Description:Relaxant effect on isolated rabbit corpus cavernosumMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Tanabe Seiyaku
Curated by ChEMBL
Tanabe Seiyaku
Curated by ChEMBL
Affinity DataEC50: 10nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Tanabe Seiyaku
Curated by ChEMBL
Tanabe Seiyaku
Curated by ChEMBL
Affinity DataEC50: 12nMAssay Description:Relaxant effect on isolated rabbit corpus cavernosumMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 20nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 30nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 30nMAssay Description:Inhibition of PDE5 in Wistar rat mesentric arteries assessed as inhibition of phenylephrine-induced contraction by measuring increase in acetylcholin...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Tanabe Seiyaku
Curated by ChEMBL
Tanabe Seiyaku
Curated by ChEMBL
Affinity DataEC50: 37nMAssay Description:Relaxant effect on isolated rabbit corpus cavernosumMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 40nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 40nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 40nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Tanabe Seiyaku
Curated by ChEMBL
Tanabe Seiyaku
Curated by ChEMBL
Affinity DataEC50: 40nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Tanabe Seiyaku
Curated by ChEMBL
Tanabe Seiyaku
Curated by ChEMBL
Affinity DataEC50: 42nMAssay Description:Relaxant effect on rabbit corpus cavernosal tissue stripsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Tanabe Seiyaku
Curated by ChEMBL
Tanabe Seiyaku
Curated by ChEMBL
Affinity DataEC50: 44nMAssay Description:Relaxant effect on rabbit corpus cavernosal tissue stripsMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Tanabe Seiyaku
Curated by ChEMBL
Tanabe Seiyaku
Curated by ChEMBL
Affinity DataEC50: 44nMAssay Description:Relaxant effect on isolated rabbit corpus cavernosumMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 50nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 50nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 55nMAssay Description:Inhibition of PDE5 in Wistar rat mesentric arteries assessed as inhibition of phenylephrine-induced contraction by measuring increase in acetylcholin...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 58nMAssay Description:Inhibition of PDE5 in Wistar rat mesentric arteries assessed as inhibition of phenylephrine-induced contraction by measuring increase in acetylcholin...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 60nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 63nMAssay Description:Inhibition of PDE5 in Wistar rat mesentric arteries assessed as inhibition of phenylephrine-induced contraction by measuring increase in acetylcholin...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 71nMAssay Description:Inhibition of PDE5 in Wistar rat mesentric arteries assessed as inhibition of phenylephrine-induced contraction by measuring increase in acetylcholin...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 78nMAssay Description:Inhibition of PDE5 in Wistar rat mesentric arteries assessed as inhibition of phenylephrine-induced contraction by measuring increase in acetylcholin...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 100nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 103nMAssay Description:Inhibition of PDE5 in Wistar rat mesentric arteries assessed as inhibition of phenylephrine-induced contraction by measuring increase in acetylcholin...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Tanabe Seiyaku
Curated by ChEMBL
Tanabe Seiyaku
Curated by ChEMBL
Affinity DataEC50: 130nMAssay Description:Relaxant effect on isolated rabbit corpus cavernosumMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 150nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 191nMAssay Description:Inhibition of PDE5 in Wistar rat mesentric arteries assessed as inhibition of phenylephrine-induced contraction by measuring increase in acetylcholin...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Tanabe Seiyaku
Curated by ChEMBL
Tanabe Seiyaku
Curated by ChEMBL
Affinity DataEC50: 220nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 225nMAssay Description:Inhibition of PDE5 in Wistar rat mesentric arteries assessed as inhibition of phenylephrine-induced contraction by measuring increase in acetylcholin...More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Tanabe Seiyaku
Curated by ChEMBL
Tanabe Seiyaku
Curated by ChEMBL
Affinity DataEC50: 230nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Tanabe Seiyaku
Curated by ChEMBL
Tanabe Seiyaku
Curated by ChEMBL
Affinity DataEC50: 250nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Tanabe Seiyaku
Curated by ChEMBL
Tanabe Seiyaku
Curated by ChEMBL
Affinity DataEC50: 280nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 300nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 300nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 300nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 300nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Tanabe Seiyaku
Curated by ChEMBL
Tanabe Seiyaku
Curated by ChEMBL
Affinity DataEC50: 330nMAssay Description:Inhibition of PDE5 in human platelets incubated for 30 mins using cGMP as substrate by HPLC analysis relative to sildenafilMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 350nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 350nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 400nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Rattus norvegicus)
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Laboratories Glaxo Wellcome Centre De Recherches
Curated by ChEMBL
Affinity DataEC50: 450nMAssay Description:Compound was tested for inhibition of stimulation of rat aortic smooth muscle cells (RSMC)More data for this Ligand-Target Pair