TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 1.40nMAssay Description:Effective concentration DP2 mediated expression of the adhesion molecule CD11b in eosinophilsMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 1.70nMAssay Description:Effective concentration for DP2 mediated chemotaxis in eosinophilsMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 2.65nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 3.80nMAssay Description:Effective concentration for DP2 mediated stimulation of actin polymerization in eosinophilsMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 5.10nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 6.70nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 7nMAssay Description:Effective concentration DP2 mediated expression of the adhesion molecule CD11b in eosinophilsMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 7.70nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 9.30nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 10nMAssay Description:Effective concentration for DP2 mediated chemotaxis in eosinophilsMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 10.5nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 10.7nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 11nMAssay Description:Antagonist activity at human CRTH2 receptor expressed in CEM cell assessed as inhibition of PGD2-induced cell migration after 3 hrs by transwell migr...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 11nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 11.1nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 11.9nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 12nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 12nMAssay Description:Agonist activity at human CRTh2 expressed in HEK cells assessed as forskolin-induced intracellular cAMP accumulation by ELISA based chemiluminescence...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 12.1nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 12.1nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 12.1nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 13nMAssay Description:Effective concentration for DP2 mediated stimulation of actin polymerization in eosinophilsMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 13.9nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 14.2nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 14.8nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 15.8nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 16nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 16.2nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 16.4nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 16.6nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 17nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 17.3nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 18.9nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 3.80nM EC50: 19nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 19nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 7.60nM EC50: 21nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 21.7nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 21.9nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 22.5nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataKi: 5.30nM EC50: 23nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 23.3nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 24nMAssay Description:Antagonist activity at CRTH2 in human eosinophils assessed as inhibition of PGD2-induced shape changeMore data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 25.6nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 25.7nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 26.4nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 30.7nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 34nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 36.4nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 37.2nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair
TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Florida Institute Of Technology
Curated by ChEMBL
Florida Institute Of Technology
Curated by ChEMBL
Affinity DataEC50: 37.4nMpH: 7.4 T: 2°CAssay Description:The coding sequence of human DP2 was introduced into the human Leukemic cell line K562 by electroporation and stable clones expressing DP2 were obtai...More data for this Ligand-Target Pair