Compile Data Set for Download or QSAR
maximum 50k data
Found 20 of ic50 data for polymerid = 11224,4373
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434751(CHEMBL2385579)
Affinity DataIC50:  40nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434748(CHEMBL2385600)
Affinity DataIC50:  44nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434749(CHEMBL2385586)
Affinity DataIC50:  82nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50262685(6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-...)
Affinity DataIC50:  235nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50262685(6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-...)
Affinity DataIC50:  318nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM237920(US9394285, 1)
Affinity DataIC50:  400nMAssay Description:Activation of recombinant AMPKbeta1 in cryopreserved human hepatocytes assessed as reduction in 14C-2-acetic acid incorporation after 1 hr by scintil...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM238079(US9394285, 173)
Affinity DataIC50:  420nMAssay Description:Activation of recombinant AMPKbeta1 in cryopreserved human hepatocytes assessed as reduction in 14C-2-acetic acid incorporation after 1 hr by scintil...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM36355(4-(2-(4-(3-(quinolin-4-yl)pyrazolo[1,5-a]pyrimidin...)
Affinity DataIC50:  527nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434750(CHEMBL2385596)
Affinity DataIC50:  960nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM160333(US9040694, 5)
Affinity DataIC50:  1.12E+3nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50262079(4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyri...)
Affinity DataIC50:  1.12E+3nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM36356(DMH3 | N,N-dimethyl-3-(4- (3-(quinolin-4-yl)pyrazo...)
Affinity DataIC50:  1.94E+3nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM102618(LDN-212854)
Affinity DataIC50:  2.52E+3nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50434752(CHEMBL2385582)
Affinity DataIC50:  2.68E+3nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM5410(4-(2-(4-(3-phenylpyrazolo[1,5- a]pyrimidin-6-yl)ph...)
Affinity DataIC50:  2.92E+3nMAssay Description:Kinase assays were performed using the assay kit by Reaction Biology Corp (Malvern, Pa.). The compounds were tested at 10 concentrations by 3-fold se...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50262016(4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...)
Affinity DataIC50:  7.26E+3nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50429867(CHEMBL2333365)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of AMPK (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50463100(CHEMBL4249790)
Affinity DataIC50:  1.10E+4nMAssay Description:Activation of recombinant AMPKbeta1 in cryopreserved human hepatocytes assessed as reduction in 14C-2-acetic acid incorporation after 1 hr by scintil...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50463101(CHEMBL4250253)
Affinity DataIC50:  2.50E+4nMAssay Description:Activation of recombinant AMPKbeta1 in cryopreserved human hepatocytes assessed as reduction in 14C-2-acetic acid incorporation after 1 hr by scintil...More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase subunit beta-1(Homo sapiens (Human))
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50380246(CHEMBL2017214)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of AMPKB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed