Compile Data Set for Download or QSAR
maximum 50k data
Found 69 of ic50 data for polymerid = 1279
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM12041((2S)-2-({5-[(diaminomethylidene)amino]-1-oxopentan...)
Affinity DataIC50:  5.80nMpH: 5.5 T: 2°CAssay Description:The substrate peptide terminating in AMC is processed by falcipain-2 with or without inhibitors, and the accumulation of AMC was monitored in a Labsy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50:  47nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM12042((2R,3R)-3-{[(1S)-1-[(4-carbamimidamidobutyl)carbam...)
Affinity DataIC50:  58nMpH: 5.5 T: 2°CAssay Description:The substrate peptide terminating in AMC is processed by falcipain-2 with or without inhibitors, and the accumulation of AMC was monitored in a Labsy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50157741(CHEMBL374508 | E-64 | E64)
Affinity DataIC50:  112nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM22985(Aralen | CHEMBL76 | CHLOROQUINE PHOSPHATE | Chloro...)
Affinity DataIC50:  200nMAssay Description:Inhibition of falcipain-2 in chloroquine resistant Plasmodium falciparum RKL9 schizont stage infected in human erythrocytes assessed as reduction in ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM12037(3-(4-chlorophenyl)-1-{4-[(2E)-3-(3,4,5-trimethoxyp...)
Affinity DataIC50:  1.80E+3nMpH: 5.5 T: 2°CAssay Description:The substrate peptide terminating in AMC is processed by falcipain-2 with or without inhibitors, and the accumulation of AMC was monitored in a Labsy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50461234(CHEMBL4226443)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of falcipain-2 in chloroquine resistant Plasmodium falciparum RKL9 schizont stage infected in human erythrocytes assessed as reduction in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50461235(CHEMBL4227918)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of falcipain-2 in chloroquine resistant Plasmodium falciparum RKL9 schizont stage infected in human erythrocytes assessed as reduction in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM12032(1-{4-[(2E)-3-(2H-1,3-benzodioxol-5-yl)prop-2-enoyl...)
Affinity DataIC50:  2.50E+3nMpH: 5.5 T: 2°CAssay Description:The substrate peptide terminating in AMC is processed by falcipain-2 with or without inhibitors, and the accumulation of AMC was monitored in a Labsy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM12035(3-(4-chlorophenyl)-1-{4-[(2E)-3-(2,4-dichloropheny...)
Affinity DataIC50:  2.50E+3nMpH: 5.5 T: 2°CAssay Description:The substrate peptide terminating in AMC is processed by falcipain-2 with or without inhibitors, and the accumulation of AMC was monitored in a Labsy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM12034(3-(4-chlorophenyl)-1-{4-[(2E)-3-(4-chlorophenyl)pr...)
Affinity DataIC50:  2.60E+3nMpH: 5.5 T: 2°CAssay Description:The substrate peptide terminating in AMC is processed by falcipain-2 with or without inhibitors, and the accumulation of AMC was monitored in a Labsy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM12036(3-(4-chlorophenyl)-1-{4-[(2E)-3-(2,4-difluoropheny...)
Affinity DataIC50:  2.60E+3nMpH: 5.5 T: 2°CAssay Description:The substrate peptide terminating in AMC is processed by falcipain-2 with or without inhibitors, and the accumulation of AMC was monitored in a Labsy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM12039(3-(4-chlorophenyl)-1-{4-[(2E)-3-(pyridin-3-yl)prop...)
Affinity DataIC50:  3.40E+3nMpH: 5.5 T: 2°CAssay Description:The substrate peptide terminating in AMC is processed by falcipain-2 with or without inhibitors, and the accumulation of AMC was monitored in a Labsy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM12038(3-(4-chlorophenyl)-1-{4-[(2E)-3-phenylprop-2-enoyl...)
Affinity DataIC50:  3.80E+3nMpH: 5.5 T: 2°CAssay Description:The substrate peptide terminating in AMC is processed by falcipain-2 with or without inhibitors, and the accumulation of AMC was monitored in a Labsy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50461226(CHEMBL4228534)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of falcipain-2 in chloroquine resistant Plasmodium falciparum RKL9 schizont stage infected in human erythrocytes assessed as reduction in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM12040(3-(4-methoxyphenyl)-1-{4-[(2E)-3-(pyridin-3-yl)pro...)
Affinity DataIC50:  1.25E+4nMpH: 5.5 T: 2°CAssay Description:The substrate peptide terminating in AMC is processed by falcipain-2 with or without inhibitors, and the accumulation of AMC was monitored in a Labsy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50415544(CHEMBL597626)
Affinity DataIC50: >1.90E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50461237(CHEMBL4226863)
Affinity DataIC50:  2.53E+4nMAssay Description:Inhibition of falcipain-2 in chloroquine resistant Plasmodium falciparum RKL9 schizont stage infected in human erythrocytes assessed as reduction in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50461225(CHEMBL4224867)
Affinity DataIC50:  2.67E+4nMAssay Description:Inhibition of falcipain-2 in chloroquine resistant Plasmodium falciparum RKL9 schizont stage infected in human erythrocytes assessed as reduction in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50461229(CHEMBL4228490)
Affinity DataIC50:  2.71E+4nMAssay Description:Inhibition of falcipain-2 in chloroquine resistant Plasmodium falciparum RKL9 schizont stage infected in human erythrocytes assessed as reduction in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50461236(CHEMBL4228011)
Affinity DataIC50:  2.99E+4nMAssay Description:Inhibition of falcipain-2 in chloroquine resistant Plasmodium falciparum RKL9 schizont stage infected in human erythrocytes assessed as reduction in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50461239(CHEMBL4227712)
Affinity DataIC50:  3.04E+4nMAssay Description:Inhibition of falcipain-2 in chloroquine resistant Plasmodium falciparum RKL9 schizont stage infected in human erythrocytes assessed as reduction in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50461232(CHEMBL4227123)
Affinity DataIC50:  3.38E+4nMAssay Description:Inhibition of falcipain-2 in chloroquine resistant Plasmodium falciparum RKL9 schizont stage infected in human erythrocytes assessed as reduction in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50461233(CHEMBL4224976)
Affinity DataIC50:  4.16E+4nMAssay Description:Inhibition of falcipain-2 in chloroquine resistant Plasmodium falciparum RKL9 schizont stage infected in human erythrocytes assessed as reduction in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50339249((Z/E)-(S)-2-((7-chloro-2-oxoindolin-3-ylidene)meth...)
Affinity DataIC50:  4.21E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50339250((Z/E)-(S)-2-((5-chloro-2-oxoindolin-3-ylidene)meth...)
Affinity DataIC50:  4.33E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50339251((Z/E)-(S)-2-((7-chloro-2-oxoindolin-3-ylidene)meth...)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50339252((Z/E)-(S)-2-((5-chloro-2-oxoindolin-3-ylidene)meth...)
Affinity DataIC50:  4.41E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50461230(CHEMBL4224721)
Affinity DataIC50:  4.45E+4nMAssay Description:Inhibition of falcipain-2 in chloroquine resistant Plasmodium falciparum RKL9 schizont stage infected in human erythrocytes assessed as reduction in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50339253((Z/E)-(S)-2-((6-chloro-2-oxoindolin-3-ylidene)meth...)
Affinity DataIC50:  4.85E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50339254((Z/E)-(S)-N-isopentyl-2-((2-oxoindolin-3-ylidene)m...)
Affinity DataIC50:  4.99E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50339266((Z/E)-N-isopentyl-2-((2-oxoindolin-3-ylidene)methy...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50339267((Z/E)-3-((3-(7-chloroquinolin-4-ylamino)propylamin...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50339268((Z/E)-5-chloro-3-((3-(7-chloroquinolin-4-ylamino)p...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50339269((Z/E)-6-chloro-3-((3-(7-chloroquinolin-4-ylamino)p...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50339270((Z/E)-7-chloro-3-((3-(7-chloroquinolin-4-ylamino)p...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50339271((Z/E)-3-((3-(7-chloroquinolin-4-ylamino)propylamin...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50339265((Z/E)-(S)-N-isopentyl-4-methyl-2-((1-methyl-2-oxoi...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50339264((Z/E)-(S)-N-isopentyl-4-methyl-2-((2-oxoindolin-3-...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50339263((Z/E)-(S)-ethyl 2-((2-oxoindolin-3-ylidene)methyla...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50339262((Z/E)-ethyl 2-((2-oxoindolin-3-ylidene)methylamino...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50339261(3-((phenylamino)methylene)indolin-2-one | CHEMBL16...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50339260((Z/E)-3-(benzylthiomethylene)indolin-2-one | CHEMB...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50339259((Z/E)-3-((dimethylamino)methylene)-1-methylindolin...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50339256((Z/E)-5-chloro-3-((dimethylamino)methylene)indolin...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50339257((Z/E)-6-chloro-3-((dimethylamino)methylene)indolin...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50339258((Z/E)-7-chloro-3-((dimethylamino)methylene)indolin...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50339255((Z/E)-3-(N,N-Dimethylaminomethylene)indolin-2-one ...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of Plasmodium falciparum falcipain 2 incubated with compound for 10 mins before addition of 25 uM Z-Leu-Arg-AMC substrate by fluorescence ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50415543(CHEMBL589510)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFalcipain-2(Plasmodium falciparum)
Universidad Central De Venezuela

LigandPNGBDBM50415541(CHEMBL597017)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Plasmodium falciparum falcipain-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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