Compile Data Set for Download or QSAR
maximum 50k data
Found 47 of ic50 data for polymerid = 1642,1714
LigandPNGBDBM16117(3-{[2,3,5,6-tetrafluoro-4-(2-methoxyphenyl)phenyl]...)
Affinity DataIC50:  1nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16115(3-{[4-(3-ethoxyphenyl)-2,6-difluorophenyl]carbamoy...)
Affinity DataIC50:  3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16112(2-{[2,3,5,6-tetrafluoro-4-(2-methoxyphenyl)phenyl]...)
Affinity DataIC50:  8nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methyl-qui...)
Affinity DataIC50:  8nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
LigandPNGBDBM16116(3-{[4-(2-ethoxyphenyl)-2,6-difluorophenyl]carbamoy...)
Affinity DataIC50:  9nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16120(4-{[4-(2-ethoxyphenyl)-2,6-difluorophenyl]carbamoy...)
Affinity DataIC50:  10nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16121(4-({2,6-difluoro-4-[3-(trifluoromethoxy)phenyl]phe...)
Affinity DataIC50:  10nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16118(3-{[3-chloro-4-(2-methoxyphenyl)phenyl]carbamoyl}t...)
Affinity DataIC50:  12nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM16125(4-{[4-(3-ethoxyphenyl)-2,6-difluorophenyl]carbamoy...)
Affinity DataIC50:  16nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16114(3-{[2-fluoro-4-(3-methoxyphenyl)phenyl]carbamoyl}t...)
Affinity DataIC50:  44nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [30-395](Rattus norvegicus (rat))
University Of Copenhagen

LigandPNGBDBM15339(6-fluoro-2-[4-(2-fluorophenyl)phenyl]-3-methyl-qui...)
Affinity DataIC50:  127nMpH: 8.0 T: 2°CAssay Description:To determine the inhibitory potency of the drugs, the initial velocity of the DHODR-catalyzed reaction at saturating concentrations of DHO (1 mM) and...More data for this Ligand-Target Pair
LigandPNGBDBM16111(2-{[2-fluoro-4-(3-methoxyphenyl)phenyl]carbamoyl}c...)
Affinity DataIC50:  134nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16113(3-[(4-phenylphenyl)carbamoyl]thiophene-2-carboxyli...)
Affinity DataIC50:  303nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM16126(4-{[2-fluoro-4-(3-methoxyphenyl)phenyl]carbamoyl}f...)
Affinity DataIC50:  340nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16109(2-[(4-phenylphenyl)carbamoyl]cyclopent-1-ene-1-car...)
Affinity DataIC50:  410nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydroorotate dehydrogenase (quinone), mitochondrial [30-395](Rattus norvegicus (rat))
University Of Copenhagen

LigandPNGBDBM16301(3-[4-(4-chlorophenyl)cyclohexyl]naphthalene-1,2,4-...)
Affinity DataIC50:  904nMpH: 8.0 T: 2°CAssay Description:To determine the inhibitory potency of the drugs, the initial velocity of the DHODR-catalyzed reaction at saturating concentrations of DHO (1 mM) and...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16122(3-{[2-fluoro-4-(3-methoxyphenyl)phenyl]carbamoyl}t...)
Affinity DataIC50: >1.00E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16123(3-{[2-fluoro-4-(3-methoxyphenyl)phenyl]carbamoyl}t...)
Affinity DataIC50: >1.00E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16124(4-{[2-fluoro-4-(3-methoxyphenyl)phenyl]carbamoyl}t...)
Affinity DataIC50: >1.00E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM16119(4-[(4-phenylphenyl)carbamoyl]thiophene-3-carboxyli...)
Affinity DataIC50:  1.00E+3nMpH: 8.0 T: 2°CAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM15348(ChemBridge compound no. 3 | N-(2-fluorophenyl)naph...)
Affinity DataIC50:  3.40E+4nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15345(Asinex compound no. 1 | N-(2,4-dichlorophenyl)naph...)
Affinity DataIC50: >5.00E+4nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15354(Asinex compound no. 9 | N-(3,4-dichlorophenyl)-2-m...)
Affinity DataIC50:  7.20E+4nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28842(N-(3-fluoro-4-methylphenyl)-5-methyl-[1,2,4]triazo...)
Affinity DataIC50: >1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28843(N-[3-fluoro-4-(trifluoromethyl)phenyl]-5-methyl-[1...)
Affinity DataIC50: >1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28840(N-(3,4-dimethylphenyl)-5-methyl-[1,2,4]triazolo[1,...)
Affinity DataIC50: >1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28839(5-methyl-N-[4-methyl-3-(trifluoromethyl)phenyl]-[1...)
Affinity DataIC50: >1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28838(N-[4-bromo-3-(trifluoromethyl)phenyl]-5-methyl-[1,...)
Affinity DataIC50: >1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28837(N-[4-chloro-3-(trifluoromethyl)phenyl]-5-methyl-[1...)
Affinity DataIC50: >1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28819(5-methyl-N-[4-(trifluoromethoxy)phenyl]-[1,2,4]tri...)
Affinity DataIC50: >1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28817(5-methyl-N-[4-(trifluoromethyl)phenyl]-[1,2,4]tria...)
Affinity DataIC50: >1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

LigandPNGBDBM28815(N-(4-bromophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]p...)
Affinity DataIC50: >1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28814(N-(4-chlorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]...)
Affinity DataIC50: >1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28810(N-(3-chlorophenyl)-5-methyl-[1,2,4]triazolo[1,5-a]...)
Affinity DataIC50: >1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15353(2-methyl-N-(naphthalen-1-yl)-3-nitrobenzamide | Ch...)
Affinity DataIC50:  1.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15349(Asinex compound no. 4 | N-(3-bromophenyl)-2-methyl...)
Affinity DataIC50:  1.05E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15357(3-(2-methoxyphenyl)-1-naphthalen-1-ylurea | ChemBr...)
Affinity DataIC50:  1.12E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15350(ChemBridge compound no. 5 | N-(3-chloro-4-fluoroph...)
Affinity DataIC50:  1.16E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15358(3-(4-chlorophenyl)-1-quinolin-8-ylurea | Asinex co...)
Affinity DataIC50:  1.16E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15355(2-methyl-3-nitro-N-[3-(trifluoromethyl)phenyl]benz...)
Affinity DataIC50:  1.50E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24400(5-methyl-N-(naphthalen-2-yl)-[1,2,4]triazolo[1,5-a...)
Affinity DataIC50: >2.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24412(5-methyl-N-phenyl-[1,2,4]triazolo[1,5-a]pyrimidin-...)
Affinity DataIC50: >2.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15352(ChemBridge compound no. 7 | N-(3,4-difluorophenyl)...)
Affinity DataIC50:  2.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM14711(Asinex compound no. 6 | N-(3,5-Dichlorophenyl)-2-m...)
Affinity DataIC50:  2.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM24413(JMC521864 Compund DSM2 | N-(anthracen-2-yl)-5-meth...)
Affinity DataIC50: >2.00E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

LigandPNGBDBM14710(ChemBridge compound no. 2 | N-(4-Bromo-2-methylphe...)
Affinity DataIC50:  2.10E+5nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM15356(1-naphthalen-1-yl-3-[2-(trifluoromethyl)phenyl]ure...)
Affinity DataIC50: >1.00E+6nMAssay Description:The assays were carried out by using a colorimetric DCIP method, which uses the colorimetric reagent 2, 6-dichlorophenolindophenol as the final elect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed