Found 157 of ic50 data for polymerid = 1876 
Affinity DataIC50: 0.850nMAssay Description:Inhibition of dihydrofolate reductase from toxoplasma gondii.More data for this Ligand-Target Pair
Affinity DataIC50: 2nMpH: 7.4 T: 2°CAssay Description:Enzymatic activities were determined by monitoring the oxidation of NADPH at 340 nm using a 96-well microtiter plate reading spectrophotometer.More data for this Ligand-Target Pair
Affinity DataIC50: 3nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of dihydrofolate reductase from toxoplasma gondii.More data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMpH: 7.4 T: 2°CAssay Description:Enzymatic activities were determined by monitoring the oxidation of NADPH at 340 nm using a 96-well microtiter plate reading spectrophotometer.More data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMpH: 7.4 T: 2°CAssay Description:DHFRs were assayed spectrophotometrically in the reaction buffer solution containing dihydrofolate. The reaction was initiated with an amount of enzy...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMpH: 7.0 T: 2°CAssay Description:Activity was measured as a change in absorbance over time at a wavelength of 340 nm (A340), so as to monitor the disappearance of NADPH. After incuba...More data for this Ligand-Target Pair
Affinity DataIC50: 7nMpH: 7.0 T: 2°CAssay Description:Activity was measured as a change in absorbance over time at a wavelength of 340 nm (A340), so as to monitor the disappearance of NADPH. After incuba...More data for this Ligand-Target Pair
Affinity DataIC50: 7.40nMAssay Description:Inhibition of dihydrofolate reductase from toxoplasma gondii.More data for this Ligand-Target Pair
Affinity DataIC50: 8.80nMAssay Description:DHFRs were assayed spectrophotometrically in the reaction buffer solution containing dihydrofolate. The reaction was initiated with an amount of enzy...More data for this Ligand-Target Pair
Affinity DataIC50: 8.80nMAssay Description:DHFRs were assayed spectrophotometrically in the reaction buffer solution containing dihydrofolate. The reaction was initiated with an amount of enzy...More data for this Ligand-Target Pair
Affinity DataIC50: 9nMAssay Description:Inhibition of dihydrofolate reductase from toxoplasma gondii.More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:DHFRs were assayed spectrophotometrically in the reaction buffer solution containing dihydrofolate. The reaction was initiated with an amount of enzy...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of dihydrofolate reductase in Toxoplasma gondii.More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Inhibition of dihydrofolate reductase from toxoplasma gondii.More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:DHFRs were assayed spectrophotometrically in the reaction buffer solution containing dihydrofolate. The reaction was initiated with an amount of enzy...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of dihydrofolate reductase in pneumocystis carinii.More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of dihydrofolate reductase from toxoplasma gondii.More data for this Ligand-Target Pair
Affinity DataIC50: 13nMAssay Description:Inhibition of dihydrofolate reductase from pneumocystis carinii.More data for this Ligand-Target Pair
Affinity DataIC50: 16nMpH: 7.4 T: 2°CAssay Description:Enzymatic activities were determined by monitoring the oxidation of NADPH at 340 nm using a 96-well microtiter plate reading spectrophotometer.More data for this Ligand-Target Pair
Affinity DataIC50: 16nMpH: 7.4 T: 2°CAssay Description:DHFRs were assayed spectrophotometrically in the reaction buffer solution containing dihydrofolate. The reaction was initiated with an amount of enzy...More data for this Ligand-Target Pair
Affinity DataIC50: 20nMpH: 7.4 T: 2°CAssay Description:Enzymatic activities were determined by monitoring the oxidation of NADPH at 340 nm using a 96-well microtiter plate reading spectrophotometer.More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Inhibition of dihydrofolate reductase from pneumocystis carinii.More data for this Ligand-Target Pair
Affinity DataIC50: 38nMAssay Description:Inhibition of dihydrofolate reductase in pneumocystis carinii.More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of dihydrofolate reductase from pneumocystis carinii.More data for this Ligand-Target Pair
Affinity DataIC50: 42nMAssay Description:Inhibition of dihydrofolate reductase in pneumocystis carinii.More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of dihydrofolate reductase from pneumocystis carinii.More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of dihydrofolate reductase in Toxoplasma gondii.More data for this Ligand-Target Pair
Affinity DataIC50: 75nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
Affinity DataIC50: 75nMpH: 7.0 T: 2°CAssay Description:The DHFR inhibition observed with each derivative was characterized by determination and comparison of the IC50 values. IC50 determinations were perf...More data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibition of dihydrofolate reductase from pneumocystis carinii.More data for this Ligand-Target Pair
Affinity DataIC50: 86nMAssay Description:Inhibition of dihydrofolate reductase from pneumocystis carinii.More data for this Ligand-Target Pair
Affinity DataIC50: 90nMpH: 7.4 T: 2°CAssay Description:Enzymatic activities were determined by monitoring the oxidation of NADPH at 340 nm using a 96-well microtiter plate reading spectrophotometer.More data for this Ligand-Target Pair
Affinity DataIC50: 96nMAssay Description:Inhibition of dihydrofolate reductase from toxoplasma gondii.More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Inhibition of dihydrofolate reductase from toxoplasma gondii.More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of dihydrofolate reductase in Toxoplasma gondii.More data for this Ligand-Target Pair
Affinity DataIC50: 131nMAssay Description:Inhibition of dihydrofolate reductase from pneumocystis carinii.More data for this Ligand-Target Pair
Affinity DataIC50: 140nMpH: 7.4 T: 2°CAssay Description:Enzymatic activities were determined by monitoring the oxidation of NADPH at 340 nm using a 96-well microtiter plate reading spectrophotometer.More data for this Ligand-Target Pair
Affinity DataIC50: 140nMpH: 7.4 T: 2°CAssay Description:Enzymatic activities were determined by monitoring the oxidation of NADPH at 340 nm using a 96-well microtiter plate reading spectrophotometer.More data for this Ligand-Target Pair
Affinity DataIC50: 150nMpH: 7.4 T: 2°CAssay Description:Enzymatic activities were determined by monitoring the oxidation of NADPH at 340 nm using a 96-well microtiter plate reading spectrophotometer.More data for this Ligand-Target Pair
Affinity DataIC50: 150nMpH: 7.4 T: 2°CAssay Description:Enzymatic activities were determined by monitoring the oxidation of NADPH at 340 nm using a 96-well microtiter plate reading spectrophotometer.More data for this Ligand-Target Pair
Affinity DataIC50: 160nMpH: 7.4 T: 2°CAssay Description:Enzymatic activities were determined by monitoring the oxidation of NADPH at 340 nm using a 96-well microtiter plate reading spectrophotometer.More data for this Ligand-Target Pair
Affinity DataIC50: 160nMpH: 7.4 T: 2°CAssay Description:Enzymatic activities were determined by monitoring the oxidation of NADPH at 340 nm using a 96-well microtiter plate reading spectrophotometer.More data for this Ligand-Target Pair
Affinity DataIC50: 170nMpH: 7.4 T: 2°CAssay Description:Enzymatic activities were determined by monitoring the oxidation of NADPH at 340 nm using a 96-well microtiter plate reading spectrophotometer.More data for this Ligand-Target Pair
Affinity DataIC50: 196nMAssay Description:Inhibition of dihydrofolate reductase from pneumocystis carinii.More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:DHFRs were assayed spectrophotometrically in the reaction buffer solution containing dihydrofolate. The reaction was initiated with an amount of enzy...More data for this Ligand-Target Pair
Affinity DataIC50: 210nMAssay Description:Inhibition of dihydrofolate reductase from toxoplasma gondii.More data for this Ligand-Target Pair
Affinity DataIC50: 230nMAssay Description:Inhibition of dihydrofolate reductase from toxoplasma gondii.More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of dihydrofolate reductase from pneumocystis carinii.More data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Inhibition of dihydrofolate reductase from pneumocystis carinii.More data for this Ligand-Target Pair
