Compile Data Set for Download or QSAR
maximum 50k data
Found 249 of ic50 data for polymerid = 2625,2629,5356,50007925,50008002
TargetDNA gyrase subunit A(Escherichia coli)
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50521804(CHEMBL4581035)
Affinity DataIC50:  19nMAssay Description:Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandPNGBDBM50518940(CHEMBL4541988)
Affinity DataIC50:  20nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandPNGBDBM50518915(CHEMBL4583368)
Affinity DataIC50:  20nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Escherichia coli)
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50521806(CHEMBL4449908)
Affinity DataIC50:  37nMAssay Description:Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM50518948(CHEMBL4574863)
Affinity DataIC50:  40nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium bromid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139408(US8889671, 38)
Affinity DataIC50:  67nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli)
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50521803(CHEMBL4568624)
Affinity DataIC50:  82nMAssay Description:Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Escherichia coli)
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50521799(CHEMBL4459270)
Affinity DataIC50:  86nMAssay Description:Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Escherichia coli)
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50521800(CHEMBL4470688)
Affinity DataIC50:  89nMAssay Description:Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139409(US8889671, 39)
Affinity DataIC50:  97nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Staphylococcus aureus)
Angelini

Curated by ChEMBL
LigandPNGBDBM50518948(CHEMBL4574863)
Affinity DataIC50: <100nMAssay Description:Inhibition of Staphylococcus aureus ATCC 29213 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM50518915(CHEMBL4583368)
Affinity DataIC50:  100nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium bromid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139407(US8889671, 37)
Affinity DataIC50:  120nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139428(US8889671, 65)
Affinity DataIC50:  120nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli)
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50521805(CHEMBL4436644)
Affinity DataIC50:  120nMAssay Description:Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM50483022(8-Methoxy Fluoroquinolone | CHEMBL1276635)
Affinity DataIC50:  120nMAssay Description:Inhibition of DNA supercoiling activity of Escherichia coli DNA gyrase gyrA A67S mutantMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139386(US8889671, 15)
Affinity DataIC50:  130nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139388(US8889671, 17 | US8889671, 67)
Affinity DataIC50:  140nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli)
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50521801(CHEMBL4521306)
Affinity DataIC50:  150nMAssay Description:Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139443(US8889671, 47)
Affinity DataIC50:  150nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM50518924(CHEMBL4533152)
Affinity DataIC50:  150nMAssay Description:Inhibition of Escherichia coli ATCC 25922 DNA gyrase A assessed as reduction in enzyme-mediated supercoiling of relaxed pBR322 DNA by ethidium bromid...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139445(US8889671, 55)
Affinity DataIC50:  150nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139390(US8889671, 19)
Affinity DataIC50:  160nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139434(US8889671, 71)
Affinity DataIC50:  160nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139376(US8889671, 5)
Affinity DataIC50:  169nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139429(US8889671, 66)
Affinity DataIC50:  170nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139441(US8889671, 80)
Affinity DataIC50:  170nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139416(US8889671, 46)
Affinity DataIC50:  170nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139397(US8889671, 26)
Affinity DataIC50:  170nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139387(US8889671, 16)
Affinity DataIC50:  190nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139419(US8889671, 50)
Affinity DataIC50:  200nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli)
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM50521802(CHEMBL4465300)
Affinity DataIC50:  200nMAssay Description:Inhibition of Escherichia coli DNA gyrase(A2B2 tetramer) preincubated for 5 mins followed by ATP addition and measured once per minute for 20 to 30 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139393(US8889671, 22)
Affinity DataIC50:  210nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139431(US8889671, 68)
Affinity DataIC50:  220nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139404(US8889671, 34)
Affinity DataIC50:  230nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139403(US8889671, 33)
Affinity DataIC50:  260nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139415(US8889671, 45)
Affinity DataIC50:  260nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139396(US8889671, 25)
Affinity DataIC50:  260nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139399(US8889671, 29)
Affinity DataIC50:  270nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli)
University Of Leeds

Curated by ChEMBL
LigandPNGBDBM21690(1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,...)
Affinity DataIC50:  280nMAssay Description:Inhibition of Escherichia coli DNA gyrase (A2B2 tetramer) using relaxed pBR322 as substrate preincubated for 30 mins followed by enzyme addition by S...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139412(US8889671, 42)
Affinity DataIC50:  290nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139435(US8889671, 72)
Affinity DataIC50:  290nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139405(US8889671, 35)
Affinity DataIC50:  310nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139388(US8889671, 17 | US8889671, 67)
Affinity DataIC50:  330nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139447(US8889671, 61 | US8889671, 63)
Affinity DataIC50:  340nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139436(US8889671, 73)
Affinity DataIC50:  340nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139444(US8889671, 53)
Affinity DataIC50:  380nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139418(US8889671, 49)
Affinity DataIC50:  380nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139447(US8889671, 61 | US8889671, 63)
Affinity DataIC50:  380nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDNA gyrase subunit A(Escherichia coli (strain K12))
Angelini

Curated by ChEMBL
LigandPNGBDBM139410(US8889671, 40)
Affinity DataIC50:  380nMpH: 7.5Assay Description:In a black, 384-well polystyrene assay plate, 30 microliters/well of 5 nM Escherichia coli DNA gyrase A/B tetramer and 130 micrograms/mL of topologic...More data for this Ligand-Target Pair
In DepthDetails US Patent
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