Compile Data Set for Download or QSAR
maximum 50k data
Found 1807 of ic50 data for polymerid = 402,50003604,50004441,50004442,50004443
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337251((S)-5-chloro-6-(4-(1-(4-chloro-2-fluorobenzyl)pipe...)
Affinity DataIC50:  0.200nMAssay Description:Antagonist activity at human CXCR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337251((S)-5-chloro-6-(4-(1-(4-chloro-2-fluorobenzyl)pipe...)
Affinity DataIC50:  0.200nMAssay Description:Binding affinity to human CXCR3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50446659(CHEMBL3116468)
Affinity DataIC50:  0.300nMAssay Description:Binding affinity to human CXCR3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50358617(CHEMBL1921866)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [125I]CXCL10 from human CXCR3 expressed in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337250((S)-5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-y...)
Affinity DataIC50:  0.300nMAssay Description:Antagonist activity at human CXCR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50358614(CHEMBL1921863)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [125I]CXCL10 from human CXCR3 expressed in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337250((S)-5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-y...)
Affinity DataIC50:  0.300nMAssay Description:Displacement of [125I]CXCL10 from human CXCR3 expressed in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM610449(2-(3-Cyclopropyl-pyrazol-1-yl)-1-{(S)-2-hydroxymet...)
Affinity DataIC50:  0.380nMAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50310487((R)-N-(2-(ethylsulfonyl)ethyl)-2-(4-fluoro-3-(trif...)
Affinity DataIC50:  0.400nMAssay Description:Antagonist activity against human CXCR3 expressed in human PBMC assessed as inhibition of cell migration in response to IP10 in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50358616(CHEMBL1921865)
Affinity DataIC50:  0.400nMAssay Description:Displacement of [125I]CXCL10 from human CXCR3 expressed in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50371494(CHEMBL256589)
Affinity DataIC50:  0.400nMAssay Description:Displacement of [125I]IP10 from human recombinant CXCR3 receptor expressed in IL2-activated human PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50446651(CHEMBL3116476)
Affinity DataIC50:  0.400nMAssay Description:Binding affinity to human CXCR3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM610445(2-(3-Cyclopropyl-pyrazol-1-yl)-1-{(R)-2-(2-hydroxy...)
Affinity DataIC50:  0.450nMAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 3(Mus musculus)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337250((S)-5-chloro-6-(4-(1-(4-chlorobenzyl)piperidin-4-y...)
Affinity DataIC50:  0.5nMAssay Description:Antagonist activity at mouse CXCR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50310487((R)-N-(2-(ethylsulfonyl)ethyl)-2-(4-fluoro-3-(trif...)
Affinity DataIC50:  0.600nMAssay Description:Antagonist activity against human CXCR3 expressed in human PBMC assessed as inhibition of cell migration in response to MIG in bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50229439((R)-N-(1-(1-(4-cyanophenyl)-4-phenyl-1H-imidazol-2...)
Affinity DataIC50:  0.700nMAssay Description:Displacement of [125I]IP10 from human recombinant CXCR3 receptor expressed in IL2-activated human PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM228190(1-{(R)-4-[4-(2-Cyclopropyl-pyrimidin-5-yl)-2-trifl...)
Affinity DataIC50:  0.700nMpH: 7.4Assay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM610418(2-(5-Fluoro-indol-1-yl)-1-{(R)-2-hydroxymethyl-4-[...)
Affinity DataIC50:  0.700nMAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50229439((R)-N-(1-(1-(4-cyanophenyl)-4-phenyl-1H-imidazol-2...)
Affinity DataIC50:  0.700nMAssay Description:Displacement of [125I]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50446640(CHEMBL3116487)
Affinity DataIC50:  0.800nMAssay Description:Binding affinity to human CXCR3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50310487((R)-N-(2-(ethylsulfonyl)ethyl)-2-(4-fluoro-3-(trif...)
Affinity DataIC50:  0.800nMAssay Description:Antagonist activity against human CXCR3 expressed in human PBMC assessed as inhibition of cell migration in response to ITAC in RPMI bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50358615(CHEMBL1921864)
Affinity DataIC50:  0.800nMAssay Description:Displacement of [125I]CXCL10 from human CXCR3 expressed in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50358609(CHEMBL1921858)
Affinity DataIC50:  0.800nMAssay Description:Displacement of [125I]CXCL10 from human CXCR3 expressed in mouse BA/F3 cellsMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50229381((R)-N-(1-(3-(4-cyanophenyl)quinolin-2-yl)ethyl)-N-...)
Affinity DataIC50:  0.800nMAssay Description:Displacement of [125I]-IP-10 from CXCR3 receptor expressed in human PBMC in RPMI-1640 buffer supplemented with 0.5% BSAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50358609(CHEMBL1921858)
Affinity DataIC50:  0.800nMAssay Description:Binding affinity to human CXCR3 receptorMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM389791(2-Imidazo[4,5-b]pyridin-3-yl-1-{(R)-2-methyl-4-[2-...)
Affinity DataIC50:  0.850nMAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300899((R)-N-(1-(3-(4-cyanophenyl)-8-cyclopropylimidazo[1...)
Affinity DataIC50:  0.900nMAssay Description:Displacement of [125I]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300900((R)-N-(1-(3-(4-cyanophenyl)-8-methoxyimidazo[1,2-a...)
Affinity DataIC50:  0.900nMAssay Description:Displacement of [125I]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM228186(2-[3-(1-Hydroxy-ethyl)-[1,2,4]triazol-1-yl]-1-{(R)...)
Affinity DataIC50:  0.900nMpH: 7.4Assay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300907(CHEMBL576097 | N-{(R)-1-[3-(4-Cyano-phenyl)-8-cycl...)
Affinity DataIC50:  0.900nMAssay Description:Displacement of [125I]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300905(CHEMBL578192 | N-{(R)-1-[3-(4-Cyano-phenyl)-8-cycl...)
Affinity DataIC50:  0.900nMAssay Description:Displacement of [125I]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50358630(CHEMBL1921879)
Affinity DataIC50:  0.900nMAssay Description:Displacement of [125I]CXCL10 from human CXCR3 expressed in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50358619(CHEMBL1921868)
Affinity DataIC50:  0.900nMAssay Description:Displacement of [125I]CXCL10 from human CXCR3 expressed in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM389773(US9951063, 92)
Affinity DataIC50:  0.970nMAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50310487((R)-N-(2-(ethylsulfonyl)ethyl)-2-(4-fluoro-3-(trif...)
Affinity DataIC50:  1nMAssay Description:Displacement of [125I]-ITAC from human CXCR3 expressed in human PBMC after 2 hrs in RPMI buffer by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM610443(1-{(R)-2-(2-Hydroxy-ethyl)-4-[2-trifluoromethyl-4-...)
Affinity DataIC50:  1nMAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM610446(1-{(S)-2-Hydroxymethyl-4-[2-trifluoromethyl-4-(2-t...)
Affinity DataIC50:  1nMAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50446641(CHEMBL3116486)
Affinity DataIC50:  1nMAssay Description:Binding affinity to human CXCR3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM228176(2-(3-tert-Butyl-[1,2,4]triazol-1-yl)-1-{(R)-4-[4-(...)
Affinity DataIC50:  1nMpH: 7.4Assay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50229462((R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydroquin...)
Affinity DataIC50:  1nMAssay Description:Displacement of [125I]IP10 from human recombinant CXCR3 receptor expressed in IL2-activated human PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50310483((R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropyri...)
Affinity DataIC50:  1nMAssay Description:Displacement of [125I]-1P10 from human CXCR3 expressed in PBMC after 2 hrs in RPMI buffer by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50310486((R)-N-(1-(3-(4-ethoxyphenyl)-4-oxo-3,4-dihydropyri...)
Affinity DataIC50:  1nMAssay Description:Displacement of [125I]-1P10 from human CXCR3 expressed in PBMC after 2 hrs in RPMI buffer by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50310487((R)-N-(2-(ethylsulfonyl)ethyl)-2-(4-fluoro-3-(trif...)
Affinity DataIC50:  1nMAssay Description:Displacement of [125I]-1P10 from human CXCR3 expressed in PBMC after 2 hrs in RPMI buffer by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300906(CHEMBL576096 | N-{(R)-1-[3-(4-Cyano-phenyl)-8-cycl...)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [125I]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300902((R)-N-(1-(3-(4-cyanophenyl)-8-ethylimidazo[1,2-a]p...)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [125I]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50358642(CHEMBL1921891)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [125I]CXCL10 from human CXCR3 expressed in mouse BA/F3 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM610432(1-{(R)-2-(2-Hydroxy-ethyl)-4-[2-trifluoromethyl-4-...)
Affinity DataIC50:  1.10nMAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 3(Mus musculus)
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50337251((S)-5-chloro-6-(4-(1-(4-chloro-2-fluorobenzyl)pipe...)
Affinity DataIC50:  1.10nMAssay Description:Antagonist activity at mouse CXCR3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM610414(1-{(R)-2-Hydroxymethyl-4-[2-trifluoromethyl-4-(6-t...)
Affinity DataIC50:  1.10nMAssay Description:The bioactivity of compounds is tested in a fluorometric imaging plate reader (FLIPR: Molecular Devices) using engineered CHO-K1 cells expressing the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetC-X-C chemokine receptor type 3(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50300909(CHEMBL576099 | N-{(R)-1-[3-(4-Cyano-phenyl)-8-cycl...)
Affinity DataIC50:  1.10nMAssay Description:Displacement of [125I]IP10 from CXCR3 receptor expressed in PBMCMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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