Compile Data Set for Download or QSAR
maximum 50k data
Found 465 of ic50 data for polymerid = 4987
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366426(CHEMBL4161819)
Affinity DataIC50:  17nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM109760(US8609708, 44)
Affinity DataIC50:  20nMAssay Description:The inhibition of human CYP2A6-mediated 7-hydroxy coumarin formation was evaluated in the presence of 95 selected test compounds in a standard assay ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366379(CHEMBL4165249)
Affinity DataIC50:  42nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50358746(CHEMBL596015)
Affinity DataIC50:  50nMAssay Description:Inhibition of CYP2A6 in human liver microsomes assessed as inhibition of coumarin 7-hydroxylation after 30 mins preincubation by plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50037779(CHEMBL3358215)
Affinity DataIC50:  50nMAssay Description:Inhibition of human CYP2A6 in baculovirus-infected insect cell system using coumarin 7 as substrate incubated for 30 mins prior to substrate addition...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366334(CHEMBL4173133)
Affinity DataIC50:  51nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366391(CHEMBL4173088)
Affinity DataIC50:  55nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366411(CHEMBL4160749)
Affinity DataIC50:  76nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50113851((+/-)-Tranylcypromine | 2-PCPA | 2-Phenyl-cyclopro...)
Affinity DataIC50:  80nMAssay Description:The inhibition of human CYP2A6-mediated 7-hydroxy coumarin formation was evaluated in the presence of 95 selected test compounds in a standard assay ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50342656(CHEMBL1770735 | benzo[b]thiophen-2-ylmethanamine)
Affinity DataIC50:  100nMAssay Description:Inhibition of human CYP2A6 in baculovirus-infected insect cell system using coumarin 7 as substrate preincubated for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50342656(CHEMBL1770735 | benzo[b]thiophen-2-ylmethanamine)
Affinity DataIC50:  100nMAssay Description:Inhibition of CYP2A6 in human liver microsomes assessed as inhibition of coumarin 7-hydroxylation after 10 mins by plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366407(CHEMBL4169324)
Affinity DataIC50:  110nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366398(CHEMBL4164113)
Affinity DataIC50:  130nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366401(CHEMBL4169721)
Affinity DataIC50:  140nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM12348(3-(pyridin-3-yl)prop-2-yn-1-amine | CHEMBL360541 |...)
Affinity DataIC50:  160nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50188097(1-(4-Chlorobenzyl)-1H-imidazole | CHEMBL441367)
Affinity DataIC50:  160nMpH: 7.5Assay Description:To gain insight into the selectivity of the synthetic compounds for inhibition of other CYPs, we examined the major CYPs present in human liver. Prio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM12341(CHEMBL178681 | CHEMBL359657 | US8609708, 1 | US860...)
Affinity DataIC50:  160nMpH: 7.5Assay Description:To gain insight into the selectivity of the synthetic compounds for inhibition of other CYPs, we examined the major CYPs present in human liver. Prio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366399(CHEMBL4168669)
Affinity DataIC50:  160nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM12341(CHEMBL178681 | CHEMBL359657 | US8609708, 1 | US860...)
Affinity DataIC50:  170nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2A6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM12341(CHEMBL178681 | CHEMBL359657 | US8609708, 1 | US860...)
Affinity DataIC50:  172nMAssay Description:The inhibition of human CYP2A6-mediated 7-hydroxy coumarin formation was evaluated in the presence of 95 selected test compounds in a standard assay ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM12351(3-(3-methylthiophen-2-yl)pyridine | CHEMBL179669 |...)
Affinity DataIC50:  200nMpH: 7.5Assay Description:To gain insight into the selectivity of the synthetic compounds for inhibition of other CYPs, we examined the major CYPs present in human liver. Prio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50358752(CHEMBL1922273)
Affinity DataIC50:  200nMAssay Description:Inhibition of CYP2A6 in human liver microsomes assessed as inhibition of coumarin 7-hydroxylation after 30 mins preincubation by plate readerMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM12345(CHEMBL178090 | US8609708, 2 | US8609708, 47 | [5-(...)
Affinity DataIC50:  200nMpH: 7.5Assay Description:To gain insight into the selectivity of the synthetic compounds for inhibition of other CYPs, we examined the major CYPs present in human liver. Prio...More data for this Ligand-Target Pair
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366393(CHEMBL4176100)
Affinity DataIC50:  220nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM12345(CHEMBL178090 | US8609708, 2 | US8609708, 47 | [5-(...)
Affinity DataIC50:  268nMAssay Description:The inhibition of human CYP2A6-mediated 7-hydroxy coumarin formation was evaluated in the presence of 95 selected test compounds in a standard assay ...More data for this Ligand-Target Pair
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM12345(CHEMBL178090 | US8609708, 2 | US8609708, 47 | [5-(...)
Affinity DataIC50:  270nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2A6More data for this Ligand-Target Pair
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366435(CHEMBL4161400)
Affinity DataIC50:  290nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50037778(CHEMBL3358192)
Affinity DataIC50:  300nMAssay Description:Inhibition of human CYP2A6 in baculovirus-infected insect cell system using coumarin 7 as substrate preincubated for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366408(CHEMBL4176506)
Affinity DataIC50:  300nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366414(CHEMBL4172017)
Affinity DataIC50:  330nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM109753(US8609708, 29 | US8609708, 38)
Affinity DataIC50:  330nMAssay Description:The inhibition of human CYP2A6-mediated 7-hydroxy coumarin formation was evaluated in the presence of 95 selected test compounds in a standard assay ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM109754(US8609708, 32)
Affinity DataIC50:  360nMAssay Description:The inhibition of human CYP2A6-mediated 7-hydroxy coumarin formation was evaluated in the presence of 95 selected test compounds in a standard assay ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM109748(CHEMBL179477 | US8609708, 22 | US8609708, 8)
Affinity DataIC50:  360nMAssay Description:The inhibition of human CYP2A6-mediated 7-hydroxy coumarin formation was evaluated in the presence of 95 selected test compounds in a standard assay ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366335(CHEMBL4165895)
Affinity DataIC50:  380nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366392(CHEMBL4172417)
Affinity DataIC50:  390nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50037721(CHEMBL3358207)
Affinity DataIC50:  400nMAssay Description:Inhibition of human CYP2A6 in baculovirus-infected insect cell system using coumarin 7 as substrate incubated for 30 mins prior to substrate addition...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50037776(CHEMBL3358193)
Affinity DataIC50:  400nMAssay Description:Inhibition of human CYP2A6 in baculovirus-infected insect cell system using coumarin 7 as substrate preincubated for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50037779(CHEMBL3358215)
Affinity DataIC50:  400nMAssay Description:Inhibition of human CYP2A6 in baculovirus-infected insect cell system using coumarin 7 as substrate preincubated for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50037774(CHEMBL3358194)
Affinity DataIC50:  400nMAssay Description:Inhibition of human CYP2A6 in baculovirus-infected insect cell system using coumarin 7 as substrate preincubated for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50037782(CHEMBL3358223)
Affinity DataIC50:  400nMAssay Description:Inhibition of human CYP2A6 in baculovirus-infected insect cell system using coumarin 7 as substrate preincubated for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366394(CHEMBL4159065)
Affinity DataIC50:  400nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366395(CHEMBL4175869)
Affinity DataIC50:  410nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366400(CHEMBL4171984)
Affinity DataIC50:  440nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366403(CHEMBL4164142)
Affinity DataIC50:  460nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50037714(CHEMBL3358204)
Affinity DataIC50:  500nMAssay Description:Inhibition of human CYP2A6 in baculovirus-infected insect cell system using coumarin 7 as substrate incubated for 30 mins prior to substrate addition...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50037773(CHEMBL3358195)
Affinity DataIC50:  500nMAssay Description:Inhibition of human CYP2A6 in baculovirus-infected insect cell system using coumarin 7 as substrate preincubated for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM12348(3-(pyridin-3-yl)prop-2-yn-1-amine | CHEMBL360541 |...)
Affinity DataIC50:  514nMAssay Description:The inhibition of human CYP2A6-mediated 7-hydroxy coumarin formation was evaluated in the presence of 95 selected test compounds in a standard assay ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50366402(CHEMBL4172462)
Affinity DataIC50:  550nMAssay Description:Inhibition of CYP2A6 in human liver microsomes using coumarin as substrate preincubated for 5 mins followed by addition of NADPH-regenerating system ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50159272(2-Bromo-naphthalene | 2-bromonaphthalene | CHEMBL1...)
Affinity DataIC50:  550nMAssay Description:Inhibitory concentration against human cytochrome P450 2A6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2A6(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM50159272(2-Bromo-naphthalene | 2-bromonaphthalene | CHEMBL1...)
Affinity DataIC50:  550nMAssay Description:Inhibition of human CYP2A6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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